Theoretical study of spermatozoa sorting by dielectrophoresis or magnetophoresis with supervised learning by Koh, James Boon Yong

“…The difference in velocity distribution between normal and abnormal sperm cells can be widened using an external field to double the proportion of normal ones, with at least half the number of normal spermatozoa in the original sample retained. …”
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Econometric analyses of liquefied petroleum gas and product tanker shipping markets by Bai, Xiwen

“…Specifically, the relationship among very large gas carrier (VLGC) market variables, VLGC freight rate dependency with product price arbitrage and oil prices, and VLGC vessel destination choices have been studied. Last but not least, a disaggregate approach has been used to study the freight relationships across major routes for the product tanker market. …”
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Predicting clinical outcome of neuroblastoma patients using an integrative network-based approach by Rajapakse, Jagath Chandana, Azuaje, Francisco, Tranchevent, Léon-Charles, Nazarov, Petr V., Kaoma, Tony, Schmartz, Georges P., Muller, Arnaud, Kim, Sang-Yoon

“…In particular, we observe that models built on our network-based approach perform at least as well as state of the art models. We furthermore explore the effectiveness of various topological features and observe, for instance, that redundant centrality metrics can be combined to build more powerful models. …”
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Sparse low-rank matrix approximation for data compression by Hou, Junhui, Chau, Lap-Pui, Magnenat-Thalmann, Nadia, He, Ying

“…Technically, we formulate SLRMA as a constrained optimization problem, i.e., minimizing the approximation error in the least-squares sense regularized by the 0-norm and orthogonality, and solve it using the inexact augmented Lagrangian multiplier method. …”
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Holocene rate of slip and tentative recurrence interval for large earthquakes on the San Andreas fault, Cajon Pass, southern California by Sieh, Kerry, Weldon, Ray J.

“…An excavation has provided evidence for at least 2 earthquakes, and perhaps as many as 4, that caused rupture on the fault between 1290 and 1805 A.D.; it has provided tentative evidence for 6 earthquakes in about the past 1,000 yr. …”
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Laplacian embedded regression for scalable manifold regularization by Chen, Lin, Tsang, Ivor Wai-Hung, Xu, Dong

“…In particular, the manifold regularization framework has laid solid theoretical foundations for a large family of SSL algorithms, such as Laplacian support vector machine (LapSVM) and Laplacian regularized least squares (LapRLS). However, most of these algorithms are limited to small scale problems due to the high computational cost of the matrix inversion operation involved in the optimization problem. …”
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Robust engineering in maintainability of building by Ismail, Neza

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An induced population of Trypanosoma cruzi epimastigotes more resistant to complement lysis promotes a phenotype with greater differentiation, invasiveness, and release of extracel... by Rossi, Izadora, Nunes, Maria Alice Ferreira, Sabatke, Bruna, Ribas, Hennrique Taborda, Winnischofer, Sheila Maria Brochado, Ramos, Augusto Savio Peixoto, Inal, Jameel, Ramirez, Marcel I.

“…The 2R population had a favored metacyclogenesis compared with wild-type (WT) parasites. 2R metacyclic trypomastigotes had a two-fold increase in resistance to complementmediated lysis and were at least three times more infective to eukaryotic cells, probably due to a higher GP82 expression in the resistant population. …”
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Let's move with Leon: a qualitative evaluation of a UK digital intervention to improve physical activity in people with a musculoskeletal condition by Webb, Justin, Allison, Heather, Mprah, Michael

“…A total of 128 of the 184 intervention participants (70.11%) provided at least one qualitative comment over the course of the evaluation (mean number of comments per participant = 5); in total, 674 comments were received. …”
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A prospective observational study comparing rates of medical instability between adolescents with typical and atypical anorexia nervosa by Brennan, Cliona, Cini, Erica, Illingworth, Sarah, Chapman, Simon, Simic, Mima, Nicholls, Dasha, Chapman, Victoria, Simms, Conor, Hayes, Ellen, Fuller, Sarah, Orpwood, Jade, Tweedy, Nicola, Baksh, Tahmida, Astaire, Emma, Bhakta, Dee, Saglio, Eloise, Stevenson, Annie, Buchbinder, Melissa

“…Although white blood cell counts were lower in the AN group, rates of leukopaenia could not be statistically compared as a result of there being too few counts in at least one group. No incidences of hypophosphataemia were found in the sample. …”
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Seizure amelioration effect of omega-3 EPA and DHA fatty acid supplementation on patients with drug resistant epilepsy: a scoping review using the GOED clinical study database by Abuknesha, Nada R., Searle, Andrew J.

“…A supplementation period of 3 months or less was employed by 72.7% of RCTs. 54.5% of RCTs reported a positive outcome of at least 50% or more significant reduction in seizure frequency compared to placebo or baseline. 27.2% of RCTs reported significant seizure freedom in patients during or at the end of the supplementation period, compared to placebo. …”
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A preliminary investigation into the use of cannabis suppositories and online mindful compassion for improving sexual function among women following gynaecological cancer treatment by Banbury, Sam, Tharmalingam, Hannah, Lusher, Joanne, Erridge, Simon, Chandler, Chris

“…Eighty-three participants aged between 18 and 50+ years who were at least six months post-cancer treatment were randomly allocated to one of four groups, depending on whether they were already using cannabis suppositories. …”
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Optimizing mechanical ventilation: Personalizing mechanical power to reduce ICU mortality ‐ a retrospective cohort study by Alkhalifah, AS, Rumindo, K, Brincat, E, Blanchard, F, Helleberg, J, Clarke, D, Popoff, B, Duranteau, O, Mohamed, ZU, Senosy, A

“…The study included patients aged 18 and older who needed at least 48 hours of pressure-controlled mechanical ventilation. …”

Archaia Phusis: the original nature of the soul in Plato’s Middle Dialogues by Körner, H

“…Do we desire our fully realized state because it ‘belongs’ (is <em>oikeion</em>) to us or because it is good? Last but not least, what do we make of the fact that immortality and the theory of recollection seem to play no role in the <em>Symposium</em>? …”

The protocol of a clinical effectiveness trial comparing standard step-up care, early combination DMARD therapy and early use of TNF inhibitors for the treatment of moderate to sev... by Watson, M, Tillett, W, Jadon, D, Massa, MS, Francis, A, Gullick, N, Rombach, I, Sinomati, Y, Tucker, L, Coates, LC

“…</p> <p><strong>Methods and analysis:</strong> Patients with newly diagnosed PsA and at least one poor prognostic factor (polyarthritis, C-reactive protein >5 mg/dL, health assessment questionnaire >1, radiographic erosions) were randomized equally and open-label to either standard care with ‘step-up’ csDMARD therapy, initial therapy with combination csDMARDs (methotrexate with either sulfasalazine or leflunomide) or to early biologics induction therapy (adalimumab plus methotrexate). …”

Early, very high-titre convalescent plasma therapy in clinically vulnerable individuals with mild COVID-19 (COVIC-19): protocol for a randomised, open-label trial by Desmarets, M, Hoffmann, S, Vauchy, C, Rijnders, BJA, Toussirot, E, Durrbach, A, Körper, S, Schrezenmeier, E, van der Schoot, CE, Harvala, H, Brunotte, G, Appl, T, Seifried, E, Tiberghien, P, Bradshaw, D, Roberts, DJ, Estcourt, LJ, Schrezenmeier, H

“…Up to 1020 participants will be enrolled in each cohort (at least 340 with a sample size re-estimation after reaching 102 patients). …”

Canadians' opinions towards COVID-19 data-sharing: a national cross-sectional survey by Savić Kallesøe, SA, Rabbani, T, Gill, EE, Brinkman, F, Griffiths, EJ, Zawati, M, Liu, H, Palmour, N, Joly, Y, Hsiao, WWL

“…Generally supportive Canadians were characterised as being ≥50 years, with higher education, and being vaccinated against COVID-19 at least once. Vaccination status was the most influential predictor of data-sharing opinion, with respondents who were ever vaccinated being 4.20 times more likely (95% CI 3.21 to 5.48, p=0.000) to be generally supportive of data-sharing than those unvaccinated. …”

The fragmented COVID-19 therapeutics research landscape: a living systematic review of clinical trial registrations evaluating priority pharmacological interventions by McLean, ARD, Rashan, S, Tran, L, Arena, L, Lawal, A, Maguire, BJ, Adele, S, Antonio, ES, Brack, M, Caldwell, F, Carrara, VI, Charles, R, Citarella, BW, Epie, TB, Feteh, VF, Kennon, K, Makuka, GJ, Ngu, R, Nwosu, A-P, Obiesie, S, Ogbonnaa-Njoku, C, Paul, P, Richmond, C, Singh-Phulgenda, S, Strudwick, S, Tyrrell, CSB, Stepniewska, K, Strub-Wourgaft, N, White, NJ, Guérin, PJ

“…</p> <p><strong>Results:</strong> We identified 1,314 registered studies that included at least one of the 32 priority pharmacological interventions. …”

The effectiveness of individualized morphosyntactic target identification and explicit intervention using the SHAPE CPDING System for children with developmental language disorder... by Ebbels, SH, Gadd, M, Nicoll, H, Hughes, L, Burke, C, Dawson, N, Calder, SD, Frizelle, P

“…</p> <br> <p><strong>METHOD:</strong> Eight children with developmental language disorder aged 8;0-10;10 (years;months) received 10 hr of explicit individualized intervention for morphosyntax delivered in 30-min individual sessions once per week for 20 weeks. Following at least four baseline probe tests, two grammatical targets per session received explicit instruction until they reached criterion (90%), when the next target was introduced. …”

'The listening series': increasing equity, diversity and inclusion in patient and public involvement and engagement for policy research by listening to and learning from under-repr... by Bevan, C, Alderdice, F, Darby, S, Gilzean-Hughes, S, McLeish, J, Mulla, S, Plachcinski, R, Wilkinson, S, Williams, H, Rowe, R

“…Research funders prioritise equality, diversity and inclusion (EDI) in patient and public involvement and engagement (PPIE), but people who are most likely to experience poor outcomes are also those least likely to be involved in research. This paper describes our experience of setting out to understand how to overcome barriers to EDI in PPIE in the research carried out by the National Institute for Health and Care Research (NIHR) Policy Research Unit in Maternal and Neonatal Health and Care (PRU-MNHC), in a PPIE consultation project we called The Listening Series. …”