Novel nanogel formulations with good antibacterial activities against wound infections by Xu, Ray

“…Conventional antibiotics can be ineffective against these bacteria, and infection at wound sites can lead not only to mild skin and soft tissue damage, but also life-threatening situations. …”
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Enantioselective synthesis of chiral acyclic nitriles containing α-all-carbon quaternary stereocenters via synergistic palladium and phase-transfer catalysis by Guo, Cheng, Dong, Yufei, Wang, Yiyang, Du, Xuan, Ma, Runxia, Tan, Choon-Hong, Luan, Xinjun, Ren, Jingyun

“…Herein, we present a practical strategy for the asymmetric synthesis of chiral acyclic nitriles featuring α-all-carbon quaternary stereocenters, utilizing synergistic palladium and phase-transfer catalysis from allyl 2-cyanoacetates under mild conditions. This approach offers an efficient and reliable method for the in situ generation of tertiary α-cyano carbanions through intramolecular palladium-catalyzed decarboxylative allylic alkylation. …”
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The largest eigenvalue of large random matrices and its application by Han, Xiao

“…We establish the Tracy-Widom Law for $\lambda_{1}$ under some mild conditions when both $\frac{p}{m}$ and $\frac{p}{n}$ tend to some positive constants as $p\rightarrow\infty$. …”
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Rational construction of highly transparent superhydrophobic coatings based on a non-particle, fluorine-free and water-rich system for versatile oil-water separation by Gao, Shouwei, Dong, Xiuli, Huang, Jianying, Li, Shuhui, Li, Yuwei, Chen, Zhong, Lai, Yuekun

“…Moreover, because the solution is rich of water, and the surface modification condition is mild, the PDMS coating enjoys a high degree of transparency. …”
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Efgartigimod efficacy and safety in refractory myasthenia gravis: UK’s first real-world experience by Moniz Dionísio, J, Ambrose, P, Burke, G, Farrugia, ME, Garcia-Reitboeck, P, Hewamadduma, C, Hill, M, Howard, RS, Jacob, S, Kullmann, D, Leite, MI, Miller, J, Pinto, A, Pritchard, J, Riswick, T, Sathasivam, S, Thambirajah, N, Viegas, S, Norwood, F, Spillane, J

“…Side effects were generally mild. No rescue treatments were required. At the end of the study, 96% of patients remained on efgartigimod. …”

Studies on the antioxidant mechanisms of betacyanins from improved fermented red dragon fruit (Hylocereus polyrhizus) drink in HepG2 cells by Lim, Teck Wei, Lim, Renee Lay Hong, Pui, Liew Phing, Tan, Chin Ping, Ho, Chun Wai

“…The present study aimed to investigate the antioxidant mechanisms of the stabilised betacyanins in a novel RDF functional drink, Improved-FRDFD-dH2O (produced from mild, sustainable approaches) using HepG2 cell line. …”
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Enzymatic preparation of diacylglycerols: lipase screening, immobilization, characterization and glycerolysis performance by Xie, Rui, Peng, Xianwu, Lee, Yee-Ying, Xie, Pengkai, Tan, Chin-Ping, Wang, Yong, Zhang, Zhen

“…Backgrounds: Glycerolysis, with its advantages of readily available raw materials, simple operation, and mild reaction conditions, is a primary method for producing diacylglycerol (DAG). …”

Risk analysis of work posture and body mass index to musculoskeletal disorders among librarians at Universitas Airlangga by Nugraha, Adellian, Widajati, Noeroel, Guan, Ng Yee, Febriyanto, Eka Cahya, Oktavia, Nurul Dewi

“…Results: The research results showed that the level of mild MSDs complaints was reported by 7 librarians (25.0%), moderate complaints by 13 librarians (46.4%), and severe complaints by 8 librarians (28.6%). …”
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Model-based glycaemic control in multicentre icus within diabetic patients: In-silico analysis by Athirah, Abdul Razak, Normy Norfiza, Abdul Razak, Norliyana, Nor Hisham Shah, Asma, Abu-Samah, Ummu Kulthum, Jamaludin, Fatanah, Mohamad Suhaimi

“…Performance was verified based on the percentage of blood glucose (BG) time in band (TIB) 6.0 – 10.0 mmol/L and safety with number of mild and severe hypoglycaemia episodes. Among the three protocols, STAR protocol showed the highest median and interquartile range % BG TIB 6.0 – 10.0 mmol/L for DM and NDM patients with 71.6 % [57.9 – 79.8] and 77.4 % [62.9 – 88.8]. …”
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Click chemistry as a versatile reaction for construction and modification of metal-organic frameworks by Li, Pei-Zhou, Wang, Xiao-Jun, Zhao,Yanli

“…The azide-alkyne 1,3-dipolar cycloaddition is usually conducted in mild conditions using diversely available substrates to generate 1,4-regioisomers of 1,2,3-triazoles as sole products in high yields, which meets the characteristics of the conceptual click chemistry and has been referred as the premier example of a click reaction. …”
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Robust multifunctional microcapsules with antibacterial and anticorrosion features by Chong, Yong Bing, Sun, Dawei, Zhang, Xin, Yue, Chee Yoon, Yang, Jinglei

“…Manually scratched microcapsules-based multifunctional coatings possess anticorrosion properties, due to the formation of corrosion inhibition layer resulted from the reaction between the released 8-HQ compound and the mild steel substrate. Additionally, after 30 days of immersion in the salt water, the microcapsules-based coatings still possess anticorrosion properties by forming corrosion inhibition layer at the scratched region.…”
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In-situ alkaline enhanced two-stage anaerobic digestion system for waste cooking oil and sewage sludge co-digestion by Yan, Wangwang, Vadivelu, Vel, Maspolim, Yogananda, Zhou, Yan

“…Anaerobic digestion is a promising way for resource recovery from waste cooking oil (WCO) due to its high bio-methanation potential. In-situ mild alkaline (pH 8) enhanced two-stage continuous stirred tank reactors (ALK-2-CSTRs) were implemented to explore its efficiency in co-digesting WCO and sewage sludge with stepwise increase of WCO in the co-substrates. …”
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On the commute travel pattern with compressed work schedule by Su, Qida, Wang, David Zhi Wei

“…At a low rate of agglomeration, it is socially beneficial to introduce CW and the system can achieve the social optimum naturally at long-run equilibrium with positive CW users, under mild assumptions. However, when the agglomeration rate is high, the social optimum is no longer achieved, and workers would stick to the normal schedule at equilibrium if the initial case without CW is considered. …”
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Gradient bandgap-tunable perovskite microwire arrays toward flexible color-cognitive devices by Fu, Yue, Yuan, Meng, Zhao, Yingjie, Dong, Meiqiu, Guo, Yangwu, Wang, Kui, Jin, Chunqi, Feng, Jiangang, Wu, Yuchen, Jiang, Lei

“…Herein, gradient bandgap-tunable perovskite microwire arrays with excellent crystallinity and pure crystallographic orientation are realized by the synergy of the capillary-bridge assembly method and mild component engineering processing, yielding high-performance integrated color-cognitive devices with the spectral resolution of 14 nm ranging from 405 nm to 760 nm, responsivities over 103 A W−1, and detectivities over 1015 Jones. …”
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Uptake and safety of Sotrovimab for prevention of severe COVID-19 in a cohort and self-controlled case series study by Patone, M, Snelling, AJ, Tibble, H, Coupland, C, Sheikh, A, Hippisley-Cox, J

“…Trials have shown it to have mild to moderate side effects, however, evidence regarding its safety in real-world settings remains insufficient. …”

Optimising investigative pathways in military medicine: operational impact of a military cardiopulmonary exercise testing clinic by Holland, JL, Cowie, P, Gardner, L, Mulae, J, Richards, S, Holdsworth, D

“…Reduced exercise capacity was rare, affecting only 11% of individuals, which was borderline/mild at worst. Median peak VO2 (as a percentage of the predicted peak) was lower in the higher-risk symptom group than in the lower-risk symptom group (97.8% vs 121%; p<0.001). …”

No evidence of difference in mortality with amoxicillin versus co-amoxiclav for hospital treatment of community-acquired pneumonia by Wei, J, Uppal, A, Nganjimi, C, Warr, H, Ibrahim, Y, Gu, Q, Yuan, H, Rahman, N, Jones, N, Walker, S, Eyre, D

“…</p> <br> <p><strong>Results:</strong> remained similar across stratified analyses of mild, moderate, and severe pneumonia. Results were also similar with missing data imputed. …”

Dedicated carbon scaffolds for next generation hydrogenation chemistry and H2 evolution by Zor, C

“…Enzymes are enantio-, regio- and stereoselective, can be used in mild reaction conditions, and can be easily produced in the laboratory. …”

ECG analysis of ventricular fibrillation dynamics reflects ischaemic progression subject to variability in patient anatomy and electrode location by Martinez-Navarro, H, Bertrand, A, Doste, R, Smith, H, Tomek, J, Ristagno, G, Oliveira, RS, Weber dos Santos, R, Pandit, SV, Rodriguez, B

“…AMSA allowed the precise stratification of VF according to ischaemic severity in the remote myocardium (healthy: 23.62–24.45 mV Hz; mild ischaemia: 10.58–21.47 mV Hz; moderate ischaemia: 4.82–11.12 mV Hz). …”

Performance Evaluation of Electrode Fabricated by using FDM in DieSinking EDM by Kit, Fong Mun, Ng Yang Zu, Nicolas, Abdul Haq, Reazul Haq, Manshoor, Bukhari, Abdul Ghafir, Mohammad Fahmi, Marwah, Omar Mohd Faizan, Hoffmann, Jörg

“…Additionally, the FDM electrode was able to machine the mild steel workpiece with 1 mm infit at a peak current of 16 A and pulse-on time of 50 µs without suffering premature electrode failures such as edge failure, delamination, distortion and rupturing. …”
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