Mechanistic insights on protein aggregation and phase separation by Casablancas Antràs, V

“…Chapter 3 is concerned with the mathematical modelling challenges and presents further developments to the initial method. Finally, in chapter 4, I present the mechanisms of aggregation and inhibition obtained by applying this modelling strategy to R3 and the peptide D-TLKIVW. …”

Anticholinergic burden and cognitive function in psychosis: a systematic review and meta-analysis by Mancini, V, Latreche, C, Fanshawe, J, Varvari, I, Chambrez-Zita, Z, McGinn, N, Ana, C, Pillinge, T, McGuire, PK, McCutcheon, RA

“…A negative correlation was identified between anticholinergic burden and global cognition (r=−0.37, 95% CI=−0.48, −0.25), verbal learning (r=−0.28, 95% CI=−0.36, −0.21), visual learning (r=−0.17, 95% CI=−0.28, −0.06), working mem- ory (r=−0.22, 95% CI=−0.29, −0.14), processing speed (r=−0.24, 95% CI=−0.35, −0.13), attention (r=−0.19, 95% CI=−0.29, −0.08), executive functions (r=−0.17, 95% CI=−0.27, −0.06), and social cognition (r=−0.12, 95% CI=−0.19, −0.05), and between serological anticholinergic activity and verbal learning (r=−0.26, 95% CI=−0.38, −0.14), working memory (r=−0.19, 95% CI=−0.35, −0.03), and executive functions (r=−0.16, 95% CI=−0.27, −0.04). Finally, tapering off anticholinergic medication improved the scores in verbal learning (d=0.77, 95% CI=0.44, 1.1), working memory (d=0.94, 95% CI=0.63, 1.26), and executive functions (d=0.44, 95% CI=0.26, 0.62).…”

Transforming kernel-based learners to incorporate domain knowledge from climate science by Bouabid, S

“…We propose a Bayesian model, based on GPs and heuristics from satellite aerosol retrieval algorithms, that infers aerosol vertical extinction profiles from aerosol optical depth measurements and vertically-resolved meteorological data.</p> <br> <p>Finally, we conclude in Chapter 6 by reflecting on the work presented, discussing limitations, and directions for future work.…”

Unravelling the degradation pathways and charging mechanism in the Li-O2 battery: the role of singlet oxygen by Zor, C

“…Here, it is revealed that DMA can react with superoxide depending on the salt-solvent combination and DMAO₂, the reaction product of ¹O₂ with DMA, can degrade into by-products depending on the solvent environment. </p> <p>Finally, the stability of the electrolyte and the cathode towards ¹O₂ under electrochemical conditions and the real cause of faradaic efficiency loss are investigated. …”

Biophysical studies on the structure and function of Archaerhodopsin-3 by Vinals Camallonga, J

“…We study the activity of AR3 over long periods of illumination and address the role that chromophores bound to the protein, such as retinal or bacterioruberin, might have in the photocurrent and bleaching of the protein.</p> <p>Finally, we develop a mutant library of AR3 mutants with different spectral properties. …”

Social inclusion in the legal profession: a study of the solicitor apprenticeship by Polding, E

“…The use of an employer-led standard appears to address the risk of a ‘restrictive’ apprenticeship experience, and to provide a framework to ensure a more expansive experience. Finally, the addition of a law degree to the apprenticeship award by education providers appears to address perceptions of apprenticeships as a ‘lesser’, or more risky route, and to promote parity of esteem between the apprenticeship and more traditional graduate recruitment.…”

Integrated user-interface acceptance model for e-learning system by Ramadiani, -

“…The third phase of the research is developing UIA prototype by using Moodle v9 and MANOVA analysis to compare the difference level of twelve attributes in User Interface Acceptance toward two groups of experiment. Finally, it was found that there are significant effects between User Acceptance and groups which were obtained from knowledge, robustness, safety, communicativeness and expectation. …”
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Development of an integrated scheduling model for handling equipment in automated port container terminals by Sadeghian, Syed Hamidreza

“…In addition, results proved that the modified meta-heuristic algorithm is able to find near optimal solutions and on average, the solutions found by the GA algorithm are only 0.2% worse than the optimal solutions and in the worst case in the test cases this difference is 2.3% which is acceptable. Finally, sensitivity analysis shows that as the number of ALVs increases, the objective function decreases. …”
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Environmental and social assessments of an Island Marine Park in Malaysia by Mohd Noor, Mohd Iqbal

“…Network maps can help policy makers and implementing agency in planning and monitoring changes in tourism suppliers’ arrangements by providing a unique methodological frame for collecting and organizing data. Finally, the third essays aim to investigate the relationship between social capital dimensions and environmental behavior in marine parks and to examine the impact of cultural capital in mediating the relationship between social capital and environmental behavior. …”
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Model predictive control of combustion oscillations by Du, Jiang.

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Variability study of nanowire: a compact model application by Machavolu Kamakshi Srikanth

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Tac2Pose: Tactile object pose estimation from the first touch by Bauza, Maria, Bronars, Antonia, Rodriguez, Alberto

“…We show that even in the presence of model uncertainty, Tac2Pose is able to achieve fine accuracy comparable to when the object model is the manufacturer’s CAD (computer-aided design) model. Finally, we demonstrate the advantages of Tac2Pose compared with three baseline methods for tactile pose estimation: directly regressing the object pose with a neural network, matching an observed contact to a set of possible contacts using a standard classification neural network, and direct pixel comparison of an observed contact with a set of possible contacts. …”
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The development and application of mass-spectrometry-based tools to monitor proteome remodeling in microbes by Telusma, Bertina

“…Given the deep proteome coverage enabled by my methods, and my application of these methods in a wide variety of genetic backgrounds (6) and environmental conditions (5), these datasets also serve as a rich resource to identify conditions stimulating degradation of specific proteins, as well as the genetically defined pathways supporting these activities. Finally, in appendices 1 and 2, I highlight how these approaches can be applied across different microbial species to broadly characterize the proteomic consequences of nutrient and genetic perturbations. …”
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From Sample to Answer: Innovations in sample processing and CRISPR-based diagnostics for enhanced clinical translation and field deployment by Arizti Sanz, Jon

“…We also designed and tested multiplexed diagnostic assays for the detection and differentiation of three tick-borne pathogens in clinical samples. Finally, given the inadequacy of existing sample processing methods – and their importance to nucleic acid test deployment – we developed a high throughput experimental workflow to analyze the effects of chemical reagents on diagnostic assay performance and nuclease activity in patient samples using a commercially available microfluidic platform. …”
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Designing for Connection with Inner Processes by Mindel, Jessica Rachel

“…Prototypes include Sjuzet, a compass that anchors the latent space of a user's creative writing to a local map in order to prompt reflection as a user physically wanders through memories, and Pull It Together, a material speculation on textile swatches whose wear and tear modulates to correspond to invisible sociocultural tensions. Finally, I shift my focus to explicitly, informatively trading inner processes in my design of Metaswap, an asynchronous, written activity in which strangers compare annotations about inner processes that arise as they tell personal stories about an uncertainty they are working to resolve in their lives. …”
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Nanoscale Origins of Thermal Transport Phenomena for Hybrid Layered Perovskites by Dahod, Nabeel S.

“…Specifically, lead bromide 2D LHPs exhibit structure-property relationships characteristic of ballistic phonon transport within isolated subphases and diffuse scattering at the organic-inorganic interfaces between layers. Finally, I report the first measurements of the vibrational spectrum for 2D LHPs via low frequency Raman spectroscopy. …”
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Development of a building-specific life cycle sustainability assessment model by Liu, Siyu

“…Accordingly, suggestions were given on characterizing uncertainties through GSA. Finally, an integrated LCSA model was established based on fuzzy ELECTRE III method. …”
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Design, fabrication and characterization of organic-inorganic hybrid solar cells by Ahmed Ali Said Ahmed

“…The achieved findings in this thesis include the following: (1) Six NDI-based molecules have been designed and synthesized as electron transporting layers in inverted perovskite solar cells; (2) Two pyrene-based molecules were designed and synthesized as electron transporting layers; (3) The effect of sulfur position in pyrene-based molecules was investigated (4) Three N-type conjugated polymers were explored as electron transporting layer (5) The effect of embedded sp2-nitrogen in donor and acceptors of conjugated polymer was explored and (6) Tellurium tetraiodide was explored as a promising light absorber in solar cells. Finally, summary was provided, as well as the recommendations for current and future work were involved in last chapter.…”
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Shear-flow characteristics of rock fractures and implications for injection-induced seismicity by Ji, Yinlin

“…The optimization of hydraulic stimulation strategies is finally inspired by the in-depth understanding of injection-induced seismicity. …”
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Boon or bane? : The role of filial piety, relationship quality, caregiver gender on work-family interface among working caregivers of the elderly by Leong, Anthony Xueheng

“…A three-way interaction between relationship quality (closeness to care recipient; CCR), CR and work-family interface in predicting caregiver wellbeing (vitality) was also studied. Finally, gender was considered in a three-way interaction between PO and work-family interface in predicting caregiver wellbeing (vitality). …”
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