Optimized core design of a supercritical carbon dioxide-cooled fast reactor by Handwerk, Christopher S. (Christopher Stanley), 1974-

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Time-restricted feeding modulates the DNA methylation landscape, attenuates hallmark neuropathology and cognitive impairment in a mouse model of vascular dementia by Selvaraji, Sharmelee, Efthymios, Motakis, Foo, Roger Sik Yin, Fann, David Y., Lai, Mitchell Kim Peng, Chen, Christopher Li Hsian, Lim, Kah-Leong, Arumugam, Thiruma V.

“…Modulation of DNA methylation patterns in the cortex of AL CCH mice was re-modelled and signs of reversal was observed in IF CCH mice across all three timepoints. …”
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Homocysteine metabolism pathway is involved in the control of glucose homeostasis: a cystathionine beta synthase deficiency study in mouse by Cruciani-Guglielmacci, Céline, Meneyrol, Kelly, Denom, Jessica, Kassis, Nadim, Rachdi, Latif, Makaci, Fatna, Migrenne-Li, Stéphanie, Daubigney, Fabrice, Georgiadou, Eleni, Denis, Raphaël G., Sanchez-Archidona, Ana Rodriguez, Paul, Jean-Louis, Thorens, Bernard, Rutter, Guy A., Magnan, Christophe, Le Stunff, Hervé, Janel, Nathalie

“…We evidenced a defect in the stimulated insulin secretion in CBS+/- mice with mild and intermediate HHcy, while mice with intermediate HHcy under HFD presented an improvement in insulin sensitivity that compensated for the decreased insulin secretion and permitted them to maintain a glucose tolerance similar to the CBS+/+ mice. …”
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Characterizing the function of the Arl15 gene and its role in the development of metabolic traits by Bai, Y

“…</p> <p>CRISPR/Cas9 germline knockout of Arl15 showed that homozygous KO mice die postnatally due to a complete cleft palate while heterozygous KO female mice have reduced fat mass on a normal diet. …”

Telomere oxidation status (TOS) is correlated with relative telomere length (RTL) across different mouse tissues but not with nicotinamide nucleotide transhydrogenase (Nnt) status by Kidd, Elliot, Meimaridou, Eirini, Walley, Andrew, Fairbrother, Una

“…We investigated whether Nnt deficient mice have reduced TL and display markers of TOS compared to WT and rescued mice and whether this was tissue specific.…”
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Automatic test chip set by Chin, Edward Hsi Ling.

“…In this project, the fundamental functions and basic circuitry of an universal pin electronics are investigated and designed.…”
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Modeling distance-dependent individual head-related transfer functions in the horizontal plane using frontal projection headphones by Sunder, Kaushik, Gan, Woon-Seng, Tan, Ee-Leng

“…Soc. 61, 989–1000] project the sound directly onto the pinnae from the front, and thus inherently create listener's idiosyncratic pinna cues at the eardrum. …”
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Loss of caveolin-1 impairs light flicker-induced neurovascular coupling at the optic nerve head by Loo, Jing Hong, Lee, Ying Shi, Woon, Chang Yi, Yong, Victor H. K., Tan, Bingyao, Schmetterer, Leopold, Chong, Rachel S.

“…Cav-1 KO mice exhibited higher IOP and lower pSTR amplitude. …”
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Anti-leukaemic and chemotherapy supportive effects of berberis vulgaris l. Fruit crude extract on in vitro and in vivo models by Saedi, Tayebeh Azam

“…In contrast, the amount of WBC decreased dramatically in mice treated with BVFCE, and doxorubicin compared to the mice group without treatment, which showed a high number of leukaemic cells. …”
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A 1-bit 16×16 reconfigurable intelligent surfaces array for C-band by Zhang, Yucheng

“…RIS array is achieved by combining a number of basic elements together with PIN diodes which control the on and off state of RIS units. …”
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Behind every domain there is a shift: adapting distortion-aware vision transformers for panoramic semantic segmentation by Zhang, J, Yang, K, Shi, H, ReiB, S, Peng, K, Ma, C, Fu, H, Torr, PHS, Wang, K, Stiefelhagen, R

“…Third, aside from Pinhole-to-Panoramic ( Pin2Pan ) adaptation, we create a new dataset (SynPASS) with 9,080 panoramic images, facilitating Synthetic-to-Real ( Syn2Real ) adaptation scheme in 360∘&nbsp;imagery. …”

Exploring the induction of preproinsulin-specific Foxp3+ CD4+ Treg cells that inhibit CD8+ T cell-mediated autoimmune diabetes by DNA vaccination by Stifter, Katja, Schuster, Cornelia, Schlosser, Michael, Boehm, Bernhard Otto, Schirmbeck, Reinhold

“…TGF-β expression was significantly enhanced in the Foxp3(+) CD25(+) Treg cell population of vaccinated/ppins-primed mice. Ablation of Treg cells in vaccinated/ppins-primed mice by anti-CD25 antibody treatment abolished the protective effect of the vaccine and enabled diabetes induction by pCI/ppins. …”
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Reverse translational approaches to population neuroimaging: using rodent models to interpret genetic associations with MRI by Tisca, C

“…The genetic similarity between humans and mice means we can measure and compare equivalent phenotypes across species. …”

Dysfunctional cardiac energy transduction, mitochondrial oxidative stress, oncogenic and apoptotic signaling in DiNP-induced asthma in murine model by Kehinde, Samuel Abiodun, Olajide, Abosede Temitope, Fatokun, Tolulope Peter, Faroud, Dalia, Hadi, Najah R., Elgazzar, Ahmed M., James, Adewale Segun, Ashour, Mohamed H. Mazhar

“…In the current study, we assessed the crosstalk between DiNP-induced asthma and cardiac cellular respiration, oxidative stress, apoptotic potential, and induction of oncogenic factors. Ten male BALB/c mice with a weight range of 20–30 g were divided into two groups, each comprising five mice. …”
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Determination of the life span of inflammatory dendritic cells by Tay, Yong Long

“…Due to the lack of a proper Plet-1 knockout mice model previously, cell ablation study of Plet-1+ DCs was not possible. …”
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Experimental studies of melting PCM in a heat sink by Muhammad Azrin Sa'ad.

“…The heat sink design that was the focus of this study is based on the pin finned heat sink design. Experiments mainly pertaining to the characteristics of the melting PCM in the heat sinks were observed and recorded to further understand the behaviours and characteristics of the melting PCM. …”
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Smart sleep monitoring: sparse sensor-based spatiotemporal CNN for sleep posture detection by Hu, Dikun, Gao, Weidong, Ang, Kai Keng, Hu, Mengjiao, Chuai, Gang, Huang, Rong

“…Sleep quality is heavily influenced by sleep posture, with research indicating that a supine posture can worsen obstructive sleep apnea (OSA) while lateral postures promote better sleep. …”
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Pharmacological PPARβ/δ activation upregulates VLDLR in hepatocytes by Zarei, Mohammad, Barroso, Emma, Palomer, Xavier, Escolà-Gil, Joan Carles, Cedó, Lidia, Wahli, Walter, Vázquez-Carrera, Manuel

“…Finally, treatment with another PPARβ/δ agonist increased VLDLR levels in the liver of wild-type mice, but not PPARβ/δ-deficient mice, confirming the regulation of hepatic VLDLR by this nuclear receptor. …”
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Lasting dynamic effects of the psychedelic 2,5-dimethoxy-4- iodoamphetamine ((±)-DOI) on cognitive flexibility by Sabanovic, M, Lazari, A, Blanco Pozo, M, Tisca, C, Tachrount, M, Martins Bach, A, Lerch, J, Walton, M, Bannerman, D

“…Strikingly, (±)-DOI-treated mice started learning from reward omissions, a unique strategy not typically seen in mice in this task, suggesting heightened sensitivity to previously overlooked cues. …”

Investigation of the effects of Anti-Müllerian Hormone on preventing Doxorubicin-induced primordial follicle loss by Wei, X

“…Follicular damage caused by DXR was also demonstrated in adult mouse ovaries in vivo but not in human pre-pubertal ovarian tissue xenotransplanted into mice. Although there were trends, there was no significant effect of AMH treatment alone on inhibiting primordial follicle activation in mouse ovarian tissue (in vitro and in vivo) or human ovarian tissue (xenotransplanted into mice). …”