Force transduction through the bacterial cell envelope by Williams-Jones, D

“…Overall, this work reveals the function, distribution, conservation and organisation of bacterial Tol-Pal systems and their likely evolutionary origin. I also propose a model for the mechanism by which these protein machines use proton flux to stabilise the outer membrane in <em>E. coli</em>.…”

Agamben's understanding of time and its implications for Christology by Wright, O

“…With a theological performance of temporality, Agamben stands closer alongside the likes of Jean-Yves Lacoste, Jean-Luc Marion and Jean-Louis Chrétien than he does with his more usually recognised contemporaries Žižek and Badiou.…”

Goblet cell differentiation in colorectal cancer by Abdullayeva, G

“…We suggest that in the group 4 cell lines, MUC2 is most likely methylated as opposed to other group cell lines that might be regulated by demethylation of transcription factors, such as ATOH1 and HES1.…”

Behaviours and attitudes in response to the COVID-19 pandemic: insights from a cross-national Facebook survey by Perrotta, D, Grow, A, Rampazzo, F, Cimentada, J, Del Fava, E, Gil-Clavel, S, Zagheni, E

“…We found gender-specific patterns: women showed higher threat perceptions, lower confidence in the healthcare system, and were more likely to adopt preventive behaviours. Finally, we also found that older people perceived higher threat to themselves, while all respondents were strongly concerned about their family.…”

Modelling frequency-based neural responses to deep brain stimulation in Parkinson’s disease by Sermon, JJ

“…Improvements in therapeutic outcome as well as side effects can likely be addressed through real time adaptation to both patient and pathology. …”

Long COVID and cardiovascular disease: a prospective cohort study by Lawson, CA, Moss, AJ, Arnold, JR, Bagot, C, Banerjee, A, Berry, C, Greenwood, J, Hughes, AD, Khunti, K, Mills, NL, Neubauer, S, Raman, B, Sattar, N, Leavy, OC, Richardson, M, Elneima, O, McAuley, HJ, Shikotra, A, Singapuri, A, Sereno, M, Saunders, R, Harris, V, Houchen-Wolloff, L, Greening, NJ, Harrison, E, Docherty, AB, Lone, NI, Quint, JK, Chalmers, J, Ho, L-P, Horsley, A, Marks, M, Poinasamy, K, Evans, R, Wain, LV, Brightling, C, McCann, GP

“…Compared with controls (n=718), patients with CVD and cardiovascular risk factors were older and more likely to have had severe COVID-19. Full recovery was significantly lower at 12 months in patients with CVD (adjusted OR (aOR) 0.62, 95% CI 0.43 to 0.89) and cardiovascular risk factors (aOR 0.66, 95% CI 0.50 to 0.86).…”

Characterising the functional role of GATA1short isoform in normal and malignant haematopoiesis by Cruz Hernandez, D

“…These defects were most likely explained by sustained expression of GATA2, RUNX1 and NFE2 among other genes. …”

External validation of the QCovid risk prediction algorithm for risk of COVID-19 hospitalisation and mortality in adults: national validation cohort study in Scotland by Simpson, CR, Robertson, C, Kerr, S, Shi, T, Vasileiou, E, Moore, E, McCowan, C, Agrawal, U, Docherty, A, Mulholland, R, Murray, J, Ritchie, LD, McMenamin, J, Hippisley-Cox, J, Sheikh, A

“…<p><strong>Conclusions</strong></p> Version 1 of the QCovid algorithm showed high levels of discrimination in predicting the risk of COVID-19 hospitalisations and deaths in adults resident in Scotland for the original two time periods studied, but is likely to need ongoing recalibration prospectively.…”

Prussian Blue analogue materials for magnetic and energy storage applications by Schart, M

“…A combination of magnetic measurements reveal that the magnetic ordering temperature is below room temperature, likely limited by the material’s small particle size. …”

Developing a personalized heterologous prime boost vaccination strategy for tumor therapy by Ramirez-Valdez, RA

“…The limited success of therapeutic cancer vaccines to date is likely due to sub-optimal generation of anti-tumor CD8 T cells and insufficient tumor microenvironment (TME) modulation. …”

Maternal postpartum six-week check and short-term health outcomes for women with hypertensive disorders in pregnancy: an observational study using the Clinical Practice Research Da... by Ramakrishnan, R, Korb, D, Li, Y, Knight, M, Carson, C

“…The proportion of women who received a SWC check was highest in 2007 (66.8%) but subsequently decreased. Women were less likely to have a SWC record if they were younger, of a minoritised ethnicity, living in more deprived areas, were multiparous, had severe HDP, preterm birth, caesarean birth, or had a low birthweight baby. …”

Industrial policy refraction: how corporate strategy shapes development outcomes in Brazil by Zylberberg, E

“…</p> <p>I introduce the inductively derived concept of <em>industrial policy refraction</em>, proposing that foreign firms respond to host countries' industrial policies in ways that are consonant with their corporate strategies; that centralized firms are less likely to comply with a host government's demands than are decentralized firms. …”

Molecular and physiological consequences of prematurity and blood pressure elevation on the young adult left ventricular stress response by Huckstep, O

“…Collectively, these findings suggest preterm-born young adults have reduced myocardial functional reserve which likely contributes to risk of future disease including heart failure. …”

Early Neoarchean geodynamic regime in the North China Craton: constraints from 2.7 Ga granitoids in the southern Jilin terrane by Liu, J, Zhang, H, Palin, RM, Liu, Z, Zhang, J, Cheng, C, Liu, X, Zhao, C

“…Combined with previous studies, we suggest that the North China Craton underwent significant crustal growth during the early Neoarchean, which was likely attributed to the synergistic effects of waning mantle plume activity and the coeval onset of plate tectonics.…”

Belgrave's quest for moral order in Bahrain, 1926-1957 by Fakhro, E

“…It shows how colonial officials responsible for exercising authority over Bahrain viewed these trends with alarm, as likely to spur a broader process of social decline, and ultimately bring about challenges to Britain’s political legitimacy in Bahrain.…”

Building fabric improvement and heat pump deployment: a set of policy conundrums by Killip, G, Topouzi, M, Fawcett, T

“…Setting minimum quality standards for deployment, and a policy framework which allows for local decision-making within nationally (and internationally) determined targets is likely to be part of the answer. This paper sets out the challenge for policy in devolution and coordination, providing a set of unresolved conundrums that future policy needs to meet. …”

Perceptions of a Buruli ulcer controlled human infection model: How, who, and why? by Muhi, S, Schmidt, S, Marshall, JL, O’Brien, DP, Johnson, PDR, McCarthy, JS, Jamrozik, E, Osowicki, J, Stinear, TP

“…An M. ulcerans controlled human infection model (MuCHIM) is likely to accelerate our understanding of this otherwise neglected disease, and may be an efficient platform for testing vaccines and other interventions. …”

Controls on present-day and future rainfall over southern Africa in coupled climate models by Munday, C

“…<p>Global climate change will likely alter rainfall at a regional scale. This is a particular concern in southern Africa, where rainfall is central to socioeconomic wellbeing and where we do not understand the full complexity of the climate system. …”

The molecular pathogenesis of FUS mutations in amyotrophic lateral sclerosis using in vivo and in vitro models by Kent, L

“…</p> <p>This work suggests that mutations in <em>FUS</em> are likely to affect motor neurons even when expressed at very low levels. …”

Concept of Computational Fluid Dynamics Design and Analysis Tool for Food Industry: A Bibliometric by M. Muktiarni, M. Muktiarni, Nur Indri Rahayu, Nur Indri Rahayu, Ai Nurhayati, Ai Nurhayati, Andika Dutha Bachari, Andika Dutha Bachari, Affero Ismail, Affero Ismail

“…Completing this research will likely provide information regarding publication sources and contributions made by several scientists from various affiliates and countries worldwide.…”
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