Engineering modular platforms for rapid vaccine development by Brune, K

“…I demonstrate the modularity of this approach by covalently linking several complex, cysteine-rich malarial antigens to SpyCatcher-VLPs, such as the transmission-blocking antigen Pfs25 and the blood-stage antigen CIDR. …”

Functional genetics of cancer and congenital disorders by Zak, J

“…In summary, this work identified novel candidate pathogenic variants in developmental disorders and cancer, and explored the mechanisms underlying their respective genotype-phenotype links.</p>…”

Barriers and opportunities for WHO ‘best buys’ non-communicable disease policy adoption and implementation from a political economy perspective: a complexity systematic review by Loffreda, G, Arakelyan, S, Bou-Orm, I, Holmer, H, Allen, LN, Witter, S, Ager, A, Diaconu, K

“…</p> <p><strong>Results:</strong> Our CLD highlights a central feedback loop encompassing three vital variables: (1) the ability to define, (re)shape, and pass appropriate policy into law; (2) the ability to implement the policy (linked to the enforceability of the policy and to addressing NCD local burden); and (3) ability to monitor progress, evaluate and correct the course. …”

Characterising the functional role of GATA1short isoform in normal and malignant haematopoiesis by Cruz Hernandez, D

“…Both TAM and ML-DS are driven by mutations in the gene encoding the X-linked erythroid-megakaryocyte transcription factor GATA1 that result in truncation of 83 N-terminal amino acids to produce GATA1short (GATA1s). …”

External validation of the QCovid risk prediction algorithm for risk of COVID-19 hospitalisation and mortality in adults: national validation cohort study in Scotland by Simpson, CR, Robertson, C, Kerr, S, Shi, T, Vasileiou, E, Moore, E, McCowan, C, Agrawal, U, Docherty, A, Mulholland, R, Murray, J, Ritchie, LD, McMenamin, J, Hippisley-Cox, J, Sheikh, A

“…Primary care data were linked to reverse-transcription PCR (RT-PCR) virology testing, hospitalisation and mortality data. …”

Fracture prediction in rheumatoid arthritis: validation of FRAX with bone mineral density for incident major osteoporotic fractures by Richards, C, Stevens, R, Lix, LM, McCloskey, EV, Johansson, H, Harvey, NC, Kanis, JA, Leslie, WD

“…</p> <p><strong>Methods:</strong> Administrative data from patients receiving BMD testing were linked to the Manitoba Population Health Research Data Repository. …”

Brain markers of cumulative stress response and allostatic load in the ageing Whitehall II cohort by Zsoldos, E

“…</p> <p>This thesis thus provides some empirical support for the concept of allostatic load, linking 'everyday' stress and features of the ageing human brain.…”

Participation and cooperation in global climate governance by Rowan, SS

“…First, state participation in climate institutions is linked to their dissatisfaction. Second, patterns of participation are associated with the ambition of countries’ greenhouse gas mitigation targets in the Paris Agreement. …”

Spontaneous ventricular tachyarrhythmias in β2-adrenoceptor transgenic mice in relation to cardiac interstitial fibrosis by Nguyen, M-N, Kiriazis, H, Ruggiero, D, Gao, X-M, Su, Y, Jian, A, Han, L-P, McMullen, JR, Du, X-J

“…The number of VEBs or VT episodes correlated with age (r = 0.83 and r = 0.73) and the content of total or cross-linked collagen (r = 0.62∼0.66, all P &lt;0.01). While having no effect in younger β2-TG mice, β2-AR blockade reduced the frequency of VTA in old β2-TG mice with more severe fibrosis. …”

How economic crises affect alcohol consumption and alcohol-related health problems: A realist systematic review by de Goeij, MCM, Suhrcke, M, Toffolutti, V, van de Mheen, D, Schoenmakers, TM, Kunst, AE

“…Medical, psychological, social, and economic databases were used to search for peer-reviewed qualitative or quantitative empirical evidence (published January 1, 1990-May 1, 2014) linking economic crises or stressors with alcohol consumption and alcohol-related health problems. …”

Temporal evolution of mechanical properties in PDMS: A comparative study of elastic modulus and relaxation time for storage in air and aqueous environment by Zhang, Y, Adam, C, Rehnstrom, H, Contera, S

“…Polydimethylsiloxane (PDMS) is a soft, biocompatible polymer extensively employed in biomedical research, notable for its tunable mechanical properties achieved through cross-linking. While many studies have assessed the mechanical properties of PDMS utilizing macroscopic and microscopic methods, these analyses are often limited to freshly prepared samples. …”

Global marine flyways identified for long-distance migrating seabirds from tracking data by Davies, T, Guilford, T

“…Generally, the flyways were used bidirectionally, and individuals either followed sections of a flyway, a complete flyway, or their movements linked two or more flyways. Transhemispheric figure-of-eight routes in the Atlantic and Pacific oceans, and a circumnavigation flyway in the Southern Ocean correspond with major wind-driven ocean currents.…”

Contribution of rare chromosome 22q11.2 copy number variants to non-syndromic bicuspid aortic valve by DiGregorio, H, Mansoorshahi, S, Carlisle, SG, Tovar Pensa, C, Watts, A, McNeely, C, Sabate-Rotes, A, Yetman, A, Michelena, HI, De Backer, JFA, Mosquera, LM, Bissell, MM, Andreassi, MG, Foffa, I, Hui, DS, Caffarelli, A, Kim, YY, Citro, R, De Marco, M, Tretter, JT, McBride, KL, Body, SC, Milewicz, DM, Prakash, SK

“…This study is aimed to assess the role of rare 22q11.2 CNVs in patients with early-onset BAV (EBAV) and to determine whether these variants are linked to an increased risk of complications. Methods: Whole genome microarray genotyping was conducted on 272 patients with BAV with early onset valve or aortic disease (EBAV) and 272 biological relatives. …”

Elucidating the mechanism of mRNA transport using novel imaging technologies by Stoychev, D

“…I apply this assay to investigate a specific mRNA, <em>shot</em>, previously identified as encoding important protein regulators of synaptic development and linked to neurodevelopmental disorders.…”

Antiquity as authority: Jesus and the patriarchs in the Gospel of John by Van Dyk, SL

“…In each instance, the challenge directed to Jesus is contextually linked with his authority to offer eternal life (John 4:10, 13-14; 8:51-52). …”

Understanding health system responsiveness to public feedback at the sub-national level: Insights from Kilifi County, Kenya by Kagwanja, N, Gilson, L, Tsofa, B, Olivier, J, Leli, H, Molyneux, S

“…HFCs are formal structures with community representation linked to a health facility to support community participation in service provision and health outcomes. …”

Edible bird’s nest mitigates histological alterations in the cortexes of rats’ brains subjected to lead toxicity by Albishtue, Abdulla A., Yimer, Nurhusien, Zakaria, MD Zuki A., Haron, Abd Wahid

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Best practices and factors to enhance transfer of training in Oman by Al Ghafri, Ahmed Mohammed Issa

“…The study participants indicated that trainees‟ involvement, setting clear objectives, linking training outcomes to the workplace performance, supervisory support, evaluation assignments, post-training discussions, peers training, having supportive work climate, and performance observation as the best practices that enhance the transfer of training in Oman. …”
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Factors associated with workplace deviant behavior in a public organization in Malaysia and moderating role of religiosity by Radzali, Farah Mardiana

“…Workplace deviant behavior is a multidimensional issue which is linked to wide variety of factors. However, there are limited studies that focus on the predictors of workplace deviant behavior and factors that can reduce workplace deviant behavior. …”
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The Role Perceived Customer Value, Relational Norms, and Switching Costs in Determining Islamic Banking Customes' Loyalty in Dual Banking Environment Settings (S/O 12698) by Abdul Rahman, Maria, Ramli, Mona Fairuz

“…In addition the mediating effects of relationship quality on the links between perceived value, relational norms, and switching costs and customer loyalty, respectively have also been investiagted. …”
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