Delay-and-pay: prolonging pharmaceutical patent protection without paying the ‘price’ by Foss-Solbrekk, K

“…My doctrinal analysis establishes that the generic/biosimilar defendants’ loss is likely undercompensated and the money that national health authorities spent purchasing the more expensive, patented drug whilst the interim injunction remained in effect is not usually compensated following a patent revocation and discharged injunction. …”

Territorial movements of African lions: can waterholes shape multiple central-place territories in a savanna ecosystem? by Dejeante, R, Loveridge, A, Macdonald, D, Madlamoto, D, Chamaille-James, S, Valeix, M

“…We hypothesized that male lions would be more likely to patrol a buffer area around the territory core to defend a core area where social interactions with groupmates occur, whereas female lions would more specifically patrol hunting sites, i.e. waterhole areas. …”

Investigating the role of lysine demethylase UTX-1 in lifespan regulation of C. elegans by Guillermo, A

“…Overall, the work in this thesis, which also includes analysis of <em>cbp-1</em> (H3K27 acetyl transferase), suggests that lifespan regulation due to H3K27 modification is incredibly complex and that longevity is mediated differentially as a consequence of different doses of modifier, and in specific tissues, likely due to transcriptional changes mediated by the demethylase function of UTX-1.…”

On the hidden layer-to-layer topology of the representations of reality realised within neural networks by Gafvert, O, Grindrod, P, Harrington, HA, Higham, CF, Higham, DJ, Yim, KM

“…</p> <p><strong>Findings: </strong>We discuss some of the likely consequences of these relatively unforeseen characteristics and, in particular, the possible vulnerability of such algorithms to non-realistic perturbations. …”

The effects of different solubilizing agents on the transport and pharmacokinetic profiles of indomethacin: in vitro and in vivo approach by Siti Aisyah Zainuddin, Abdul Latip Ab Hamid, Aqila Iman Rafandi, Mashani Mohamad, Khuriah Abdul Hamid, Syed Haroon Khalid

“…No in vitro-in vivo correlation (IVIVC) was observed, likely due to the physicochemical properties of indomethacin and the complex physiological environment in the gastrointestinal (GI) tract. …”
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Investigating the inter-rater reliability and usability of telehealth for home hazard falls-risk assessment after stroke by Ainuddin, Husna Ahmad, Romli, Muhammad Hibatullah, Hamid, Tengku Aizan, Salim, Mazatulfazura S. F., Mackenzie, Lynette

“…Introduction: Stroke survivors are more likely to fall at home. A home hazard assessment may be beneficial to reduce the risk of falling; however, it is resourceful and time-intensive. …”
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Rainfall projection using CIMP6 models of extreme area in Johor by Hamid, H, Rahmat, S N, Kasmin, H, Tukimat, N N

“…This suggests that without mitigation efforts, the area will likely experience decreasing rainfall intensity due to the effects of climate change…”
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Ionic liquid based ultrasonic assisted extraction of flavonoids from Artemisia vulgaris and in vitro evaluation of anticancer activity by Lim, Jin Ru, Chua, Lee Suan, Mustaffa, Azizul Azri, Dawood, Dawood Ali Salim

“…Therefore, this technique was likely to be an efficient extraction of plant flavonoids.…”

Exploratory Study on Customer Requirement in View of Electric Vehicle Development in Malaysia: Electric Vehicles in Malaysia (S/O: 12726) by Ibrahim, Jafni Azhan, Yusoff, Rushami Zien, Osman, Nor Hasni, Mohammed Udin, Zulkifli, Shariff, Kamal Imran, Ahmad, Azhar

“…The aim of this research is to analyze potential car buyers’ awareness towards electric vehicle (EV) and examine the factors that are most likely to affect their choice for EV in Malaysia. …”
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Aeration slab study volume 2 by Rahardjo, Harianto, Indrawan, I Gde Budi, Fakhrur, Rozy Harnas

“…This would mean that the aeration slab promotes water infiltration slightly better than the asphalt pavement but is likely to be much less effective compared to soil under turf cover. …”
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Study on mechanism and influential factors of progressive collapse resistance of base-isolated structure by Bao, Chao, Zhang, Yuhang, Lv, Dahai, Wang, Huxiang, Ma, Xiaotong, Cao, Jixing, Lim, Kar Sing

“…In the case of side isolation bearing failure, due to the lack of sufficient lateral restraint, the capacity was significantly lower than other conditions, which were more likely to cause partly collapse. Therefore, setting more transfer paths to improve the structure’s resistance to progressive collapses was necessary. …”
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Comparative analysis of dehydration techniques on phytochemical and antibacterial properties on pink and purple flowers impatiens walleriana by Tan, Suat Hian, Sin, Phin Yin, Ros Azlinawati, Ramli, Mohd Hairul, Ab. Rahim, Nyuk, Ling Ma

“…Notably, the pink flower variety exhibited higher flavonoid content (0.528-0.541 mg QE/100g) than the purple variety, likely due to petal color variation. Microwave-dried leaf extracts were evaluated for antibacterial activity using the disc diffusion method. …”
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Trends and Determinants of Location of Death Due to Colorectal Cancer in the United States by Sonal, Swati, Jain, Bhav, Bajaj, Simar S., Dee, Edward C., Boudreau, Chloe, Cusack, James C., Kunitake, Hiroko, Goldstone, Robert, Bordeianou, Liliana G., Cauley MD, Christy E., Francone, Todd D., Ricciardi, Rocco, Qadan, Motaz, Berger, David L.

“…Relative to White decedents, Black, Asian, and American Indian/Alaska Native decedents were less likely to die at home and in hospice compared with hospitals. …”
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Nitrite accumulation and anammox bacterial niche partitioning in Arctic Mid-Ocean Ridge sediments by Zhao, Rui, Babbin, Andrew R, Roerdink, Desiree L, Thorseth, Ingunn H, Jørgensen, Steffen L

“…Nitrite accumulation in the two AMOR cores co-occurs with a niche partitioning between two anammox bacterial families (Candidatus Bathyanammoxibiaceae and Candidatus Scalinduaceae), likely dependent on ammonium availability. Through reconstructing and comparing the dominant anammox genomes (Ca. …”
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Accelerated synthesis of Li(Ni0.8Co0.1Mn0.1)O2 cathode materials using flame-assisted spray pyrolysis and additives by Zhang, Jianan, Muldoon, Valerie L, Deng, Sili

“…Moreover, the current work demonstrated that the shortened post calcination was benefited from lithium-embedded particles that likely improved the uniformity of lithium distribution in as-synthesized powder. …”
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Learning design for short-duration e-textile workshops: outcomes on knowledge and skills by Ioannou, Andri, Miliou, Ourania, Georgiou, Yiannis, Timotheou, Stella, Barkhuus, Louise, Rode, Jennifer

“…Educators who embrace a STEAM philosophy are more likely to endorse short workshops, integrating them in existing courses or initiatives; this could serve as a steppingstone for longer interventions and bottom-up curriculum reform. …”
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JWST sighting of decameter main-belt asteroids and view on meteorite sources by Burdanov, Artem Y., de Wit, Julien, Broz, Miroslav, Muller, Thomas G., Hoffmann, Tobias, Ferrais, Marin, Micheli, Marco, Jehin, Emmanuel, Parrott, Daniel, Hasler, Samantha N., Binzel, Richard P., Ducrot, Elsa, Kreidberg, Laura, Gillon, Michael, Greene, Thomas P., Grundy, Will M., Kareta, Theodore, Lagage, Pierre-Olivier, Moskovitz, Nicholas, Thirouin, Audrey, Thomas, Cristina A., Zieba, Sebastian

“…These asteroids were sampled from multiple asteroid families —most likely Nysa, Polana and Massalia— according to the geometry of pointings considered here. …”
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15.912 Technology Strategy, Spring 2005 by Henderson, Rebecca

“…The course should be of particular interest to those interested in managing a business for which technology is likely to play a major role, and to those interested in consulting or venture capital.…”
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Methodological, political and legal issues in the assessment of the effects of nanotechnology on human health by Schulte, Paul A, Riediker, Michael, Fatkhutdinova, Liliya, Bergamaschi, Enrico, Canu, Irina Guseva

“…Scientific challenges include the array of physicochemical parameters and ENM production conditions, the lack of universally accepted definitions of ENMs and nanotechnology workers, and the lack of information about modes of action, target organs and likely dose–response functions of ENMs. Standardisation of data collection and harmonisation of research protocols are needed to eliminate misclassification of exposures and health effects. …”
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Rapid removal of chloroform, carbon tetrachloride and trichloroethylene in water by aluminum-iron alloy particles by Xu, Jie, Pu, Yuan, Yang, Xiao Jin, Wan, Pingyu, Wang, Rong, Song, Peng, Fisher, Adrian

“…Alloying Al with Fe enhances reactivity towards chlorinated hydrocarbons' degradation and the enhancement is likely the consequence of galvanic effects between different phases (Al, Fe and intermetallic Al-Fe compounds such as Al13Fe4, Fe3Al and FeAl2) and catalytic role of these intermetallic Al-Fe compounds. …”
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