Integrated transcriptomic and proteomic profiling of responses to clinical and novel bisphosphonates by Lu, J

“…<p>Bisphosphonates have traditionally been used to treat bone resorptive disorders by inhibiting osteoclast activity. …”

Tri-layer tissue engineering heart valve based on collagen, elastin and hyaluronic acid by Ma, Z

“…Between the clinically used mechanical and bioprosthetic valves, thrombosis, calcification, and incompatibility to somatic growth have been the limiting factors. Tissue engineering heart valve scaffolds, especially those constructed with naturally derived materials, have proven biocompatible and promising candidates for future-generation heart valve replacements.…”

Sensorimotor control of Drosophila copulation by Herbert, MR

“…As with most sequences of motor action, mechanosensory inputs have long been thought to be important for the male to achieve and maintain this position,although until now we have understood very little about the function or properties ofthe sensory neurons involved.…”

Les sanctions coutumières comme gage de la paix et de la sécurité chez les traditionnalistes moundang du Nord-Cameroun by Dekane, E

“…These punishments, which have now been overturned, put witches, murderers, adulterers and other exorcists out of action, thereby promoting peace and security.…”

Indicators of Global Climate Change 2023: annual update of key indicators of the state of the climate system and human influence by Forster, PM, Smith, C, Walsh, T, Lamb, WF, Lamboll, R, Hall, B, Hauser, M, Ribes, A, Rosen, D, Gillett, NP, Palmer, MD, Rogelj, J, von Schuckmann, K, Trewin, B, Allen, M, Andrew, R, Betts, RA, Borger, A, Boyer, T, Broersma, JA, Buontempo, C, Burgess, S, Cagnazzo, C, Cheng, L, Friedlingstein, P, Gettelman, A, Gütschow, J, Ishii, M, Jenkins, S, Lan, X, Morice, C, Mühle, J, Kadow, C, Kennedy, J, Killick, RE, Krummel, PB, Minx, JC, Myhre, G, Naik, V, Peters, GP, Pirani, A, Pongratz, J, Schleussner, C-F, Seneviratne, SI, Szopa, S, Thorne, P, Kovilakam, MVM, Majamäki, E, Jalkanen, J-P, van Marle, M

“…Human-induced warming has been increasing at a rate that is unprecedented in the instrumental record, reaching 0.26 [0.2–0.4] °C per decade over 2014–2023. …”

Psychiatric comorbidities in persons with epilepsy compared with persons without epilepsy: a systematic review and meta-analysis by Kwon, C-S, Rafati, A, Ottman, R, Christensen, J, Kanner, AM, Jetté, N, Newton, CR

“…<p><strong>Importance</strong> Several psychiatric disorders have been found to occur more frequently in persons with epilepsy (PWE) than in persons without epilepsy.…”

Antihyperlipidemic and hepatoprotective effect of Zingiber cassumunar Rhizome extract in high-fat diet-induced hyperlipidemic rats: the role of antioxidant activity by Mahfudh, Nurkhasanah, Sulistyani, Nanik, Sari, Novita Sari, Sari, Indah Puspita, Dedi, Adrian, Othman, Fezah, Zakaria, Zainul Amiruddin

“…Zingiber cassumunar has been reported to contain a high antioxidant content that may provide therapeutic advantages. …”
Get full text

Effectiveness of encapsulated plant growth-promoting bacteria, Acinetobacter sp. and organic supplements on the growth and nutrient contents enhancement in chilli plant by Othman, Nur Maizatul, Hajad, Siti Solemah, Shamsuddin, Aida Soraya, Ali Tan, Kee Zuan, Saiman, Mohd Faris, Hamid, Nur’Amira

“…After 5 days, these treatments were applied to chilli seeds that had already been sowed. The plants were harvested after 40 days after sowing, and various plant growth indicators and plant nutrient analyses were measured. …”
Get full text

Profiling immune markers for identification of leukocytes in brown-marbled grouper Epinephelus fuscoguttatus (Forsskal, 1775) by Chong, Chou Min

“…Rapid expansion of mariculture of grouper however has been hampered by serious outbreaks of infectious diseases in the industry which poses a pressing need for disease prevention programs and supportive input from immunological studies on this premium fish. …”
Get full text

Identification of proteins and genes as potential biomarkers in brown-marbled grouper (Epinephelus fuscoguttatus forsskal) resistance to Vibrio sp by Low, Chen Fei

“…The gram-negative marine bacterium, Vibrio sp. has frequently been identified as the causative pathogen responsible for the infectious disease vibriosis in the marine aquaculture industry. …”
Get full text

Formulation, optimization and characterization of palm kernel oil esters nanoemulsion system containing sodium diclofenac by Rezaee, Malahat

“…Special characteristic of PKOEs which has been reported is excellent wetting behavior without the oily feeling which makes it suitable for delivery of actives. …”
Get full text

Paternal parenting behaviour, self-esteem, and psychological health of adolescents in Malaysia by Yahya, Amira Najiha

“…However, little attention has been given to how fathers influence their adolescents‟ psychological health, especially in an Asian context. …”
Get full text

Effects of carbon to nitrogen ratio and organic loading rate on biogas methane production from anaerobic digestion of food waste by Tanimu, Musa Idris

“…This study has been concerned with an investigation of biogas methane generation from the abundant food waste (FW) available in Malaysia by anaerobic digestion (AD) process at mesophilic (35oC) conditions. …”
Get full text

Molecular characterisation of alpha-thalassaemia in patients investigated for hypochromic microcytic indices in Hospital Universiti Sains Malaysia by Vijian, Divashini

“…Many genetic mutations in α- thalassaemia have been discovered, which produced wide spectrum of clinical manifestation, ranging from asymptomatic to lethal. …”
Get full text

A general and facile method for preparation of large-scale reduced graphene oxide films with controlled structures by Bi, Hengchang, Wan, Shu, Cao, Xiehong, Wu, Xing, Zhou, Yilong, Yin, Kuibo, Su, Shi, Ma, Qinglang, Sindoro, Melinda, Zhu, Jingfang, Zhang, Zhuoran, Zhang, Hua, Sun, Litao

“…Impressively, the rapid preparation of rGOF with area as large as ∼216 cm2 in only 6 h has been successfully achieved, which is significant since normally it takes several days to prepare a rGOF with small area of ∼10 cm2 by using conventional filtration method. …”
Get full text

Three-dimensional photonic topological insulator without spin-orbit coupling by Kim, Minkyung, Wang, Zihao, Yang, Yihao, Teo, Hau Tian, Rho, Junsuk, Zhang, Baile

“…Spin-orbit coupling, a fundamental mechanism underlying topological insulators, has been introduced to construct the latter's photonic analogs, or photonic topological insulators (PTIs). …”
Get full text

Multi-site benchmark classification of major depressive disorder using machine learning on cortical and subcortical measures by Belov, Vladimir, Erwin-Grabner, Tracy, Aghajani, Moji, Aleman, Andre, Amod, Alyssa R., Basgoze, Zeynep, Benedetti, Francesco, Besteher, Bianca, Bülow, Robin, Ching, Christopher R. K., Connolly, Colm G., Cullen, Kathryn, Davey, Christopher G., Dima, Danai, Dols, Annemiek, Evans, Jennifer W., Fu, Cynthia H. Y., Gonul, Ali Saffet, Gotlib, Ian H., Grabe, Hans J., Groenewold, Nynke, Hamilton, J. Paul, Harrison, Ben J., Ho, Tiffany C., Mwangi, Benson, Jaworska, Natalia, Jahanshad, Neda, Klimes-Dougan, Bonnie, Koopowitz, Sheri-Michelle, Lancaster, Thomas, Li, Meng, Linden, David E. J., MacMaster, Frank P., Mehler, David M. A., Melloni, Elisa, Mueller, Bryon A., Ojha, Amar, Oudega, Mardien L., Penninx, Brenda W. J. H., Poletti, Sara, Pomarol-Clotet, Edith, Portella, Maria J., Pozzi, Elena, Reneman, Liesbeth, Sacchet, Matthew D., Sämann, Philipp G., Schrantee, Anouk, Sim, Kang, Soares, Jair C., Stein, Dan J., Thomopoulos, Sophia I., Uyar-Demir, Aslihan, van der Wee, Nic J. A., van der Werff, Steven J. A., Völzke, Henry, Whittle, Sarah, Wittfeld, Katharina, Wright, Margaret J., Wu, Mon-Ju, Yang, Tony T., Zarate, Carlos, Veltman, Dick J., Schmaal, Lianne, Thompson, Paul M., Goya-Maldonado, Roberto

“…However, the diagnostic predictive power of the existing algorithms has been limited by small sample sizes, lack of representativeness, data leakage, and/or overfitting. …”
Get full text

An NKX2-1GFP and TP63tdTomato dual fluorescent reporter for the investigation of human lung basal cell biology by Goh, Kim Jee, Tan, Ee Kim, Lu, Hao, Roy, Sudipto, Dunn, Norris Ray

“…To address this outstanding question, in the last several years differentiation protocols incorporating human pluripotent stem cells (hPSC) have been developed to produce human basal cells in vitro with varying efficiencies. …”
Get full text

The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator by Wong, Brandon Han Siang, Shim, Heesung, Goay, Stephanie Shee Min, Ong, Seow Theng, Nur Ayuni Binte Muhammad Taib, Chai, Kelila Xin Ye, Lim, Kerry, Huang, Dachuan, Ong, Choon Kiat, Vaiyapuri, Thamil Selvan, Cheah, Yeong Cheng, Wang, Yulan, Wulff, Heike, Webster, Richard David, Shelat, Vishalkumar G., Verma, Navin Kumar

“…Genetic manipulation of T-cells to upregulate the expression of K+ channels has been shown to boost T-cell cytotoxicity in cancer. …”
Get full text

Dynamic altruistic cooperation within breast tumors by Muhammad Sufyan Bin Masroni, Lee, Kee Wah, Lee, Victor Kwan Min, Ng, Siok Bian, Law, Chao Teng, Poon, Kok Siong, Lee, Bernett Teck Kwong, Liu, Zhehao, Tan, Yuen Peng, Chng, Wee Ling, Tucker, Steven, Ngo, Lynette Su-Mien, Yip, George Wai Cheong, Nga, Min En, Hue, Susan Swee Shan, Putti, Thomas Choudary, Bay, Boon Huat, Lin, Qingsong, Zhou, Lihan, Hartman, Mikael, Loh, Tze Ping, Lakshmanan, Manikandan, Lee, Sook Yee, Tergaonkar, Vinay, Chua, Huiwen, Lee, Adeline Voon Hui, Yeo, Eric Yew Meng, Li, Mo-Huang, Chang, Chan Fong, Kee, Zizheng, Tan, Karen Mei-Ling, Tan, Soo Yong, Koay, Evelyn Siew-Chuan, Archetti, Marco, Leong, Sai Mun

“…Such behaviors are widely exemplified in nature but have been underexplored in cancer cells which are conventionally seen as selfish competitive players. …”
Get full text