Antibody-directed evolution reveals a mechanism for enhanced neutralization at the HIV-1 fusion peptide site by Banach, Bailey B, Pletnev, Sergei, Olia, Adam S, Xu, Kai, Zhang, Baoshan, Rawi, Reda, Bylund, Tatsiana, Doria-Rose, Nicole A, Nguyen, Thuy Duong, Fahad, Ahmed S, Lee, Myungjin, Lin, Bob C, Liu, Tracy, Louder, Mark K, Madan, Bharat, McKee, Krisha, O’Dell, Sijy, Sastry, Mallika, Schön, Arne, Bui, Natalie, Shen, Chen-Hsiang, Wolfe, Jacy R, Chuang, Gwo-Yu, Mascola, John R, Kwong, Peter D, DeKosky, Brandon J

“…Successive rounds of directed evolution by iterative selection of antibodies for binding to resistant HIV-1 strains establish a variant, VRC34.01_mm28, as a best-in-class antibody with 10-fold enhanced potency compared to the template antibody and ~80% breadth on a cross-clade 208-strain neutralization panel. …”
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An integrated index for the identification of diabetic retinopathy stages using texture parameters by Acharya, U. Rajendra, Ng, Eddie Yin-Kwee, Tan, Jen Hong, Sree, Subbhuraam Vinitha, Ng, Kwan-Hoong

“…Receiver operation characteristics (ROC) curves were plotted to select the best classifier. Our proposed system is able to identify the unknown class with an accuracy of 85.2%, and sensitivity, specificity, and area under curve (AUC) of 98.9%, 89.5%, and 0.972 respectively using SVM classifier with polynomial kernel of order 3. …”
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Improved lower bounds on book crossing numbers of complete graphs by Salazar, G., Pasechnik, Dmitrii V., De Klerk, Etienne.

“…Finally, we investigate the best construction known for drawing Kn in k pages, calculate the resulting number of crossings, and discuss this upper bound in light of the new results reported in this paper.…”
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A new hybrid algorithm for retinal vessels segmentation on fundus images by Dharmawan, Dhimas Arief, Li, Di, Ng, Boon Poh, Rahardja, Susanto

“…In addition, the proposed algorithm achieves the best connectivity-area-length score among the competing methods. …”
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Achieving highly efficient electrocatalytic oxygen evolution with ultrathin 2D Fe-doped nickel thiophosphate nanosheets by Liang, Qinghua, Zhong, Lixiang, Du, Chengfeng, Luo, Yubo, Zheng, Yun, Li, Shuzhou, Yan, Qingyu

“…To our knowledge, this is one of the best OER electrocatalysts in alkaline medium to date. …”
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Constraint optimisation method for the heat transfer in a wavy microchannel by Xu, Yan

“…Resulting populations from algorithms gave best-pareto-front solutions, which allowed further decision-making based on the values of objectives and feasibility of microchannel setups. …”
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Biomechanical study on arthroscopic biceps tenodesis fixation techniques by Lim, Gideon Boon Hao

“…Thus, it is important to find the best repair technique among the two different techniques through biomechanical experiments. …”
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Assignment optimization of pandemic influenza antiviral drugs in Urban pharmacies by Zhang, Chijun, Du, Zhanwei, Cai, Qing, Yu, Limin, Li, Zhaohui, Bai, Yuan

“…However, there are substantial inevitable but essential social factors (such as social unbalance, spatial unbalance and resource unbalance) needed to consider to benefit the society best. In this paper, we propose a network-perspective optimization model across multiple social scales (e.g, access, social unbalance, spatial unbalance and resource unbalance) to assign antiviral drugs to the urban dispensing pharmacies. …”
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MOF-derived nickel and cobalt metal nanoparticles in a N-doped coral shaped carbon matrix of coconut leaf sheath origin for high performance supercapacitors and OER catalysis by Jayakumar, Anjali, Antony, Rajini P., Zhao, Jun, Lee, Jong-Min

“…An asymmetric supercapacitor assembly prepared from NiCo–C-1 as the positive electrode and the nitrogen-doped carbon as the negative electrode, exhibited an energy density of up to 31.8 Wh Kg−1 for a high power density of 6.2 kW kg−1 over a potential window of 0–1.55 V. Two of our best samples were also tested for OER, giving good water oxidation kinetics, revealed by their lower Tafel slopes of around 107 mV and a low over potential (η) of around 420 mV at a current density of 10 mA cm−2. …”
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Robust fuzzy model predictive control of discrete-time Takagi–Sugeno systems with nonlinear local models by Teng, Long, Wang, Youyi, Cai, Wenjian, Li, Hua

“…Comparisons among several T-S fuzzy approaches are illustrated and show that the best settling time is achieved via the proposed method.…”
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Ultrasonic welding of novel carbon/Elium® thermoplastic composites with flat and integrated energy directors : lap shear characterisation and fractographic investigation by Bhudolia, Somen K., Gohel, Goram, Kantipudi, Jayaram, Leong, Kah Fai, Jr., Robert J. Barsotti

“…The ED integrated configuration showed the best welding results with a lap shear strength of 18.68 MPa. …”
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A Hybrid Prediction Model for Damage Warning ofA hybrid prediction model for damage warning of power transmission line under typhoon disaster Power Transmission Line Under Typhoon... by Hou, Hui, Yu, Shiwen, Wang, Hao, Xu, Yan, Xiao, Xiang, Huang, Yong, Wu, Xixiu

“…The results demonstrate that the hybrid model can effectively utilize wind speed data to obtain a more reliable prediction and achieves the best synthetic similarity to the actual damage situations.…”
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Questionnaire data analysis using information geometry by Har-Shemesh, Omri, Quax, Rick, Lansing, J. Stephen, Sloot, Peter M. A.

“…Compare to previous analysis and known anthropological knowledge we conclude that our method best discriminates between different behaviours, paving the way to dimension reduction as effective as for continuous data.…”
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Information cascades and the collapse of cooperation by Yang, Guoli, Csikász-Nagy, Attila, Waites, William, Xiao, Gaoxi, Cavaliere, Matteo

“…We show that promiscuous decisions (high sensitivity, low specificity) are advantageous for cooperation when the strength of competition is weak; however, if competition is strong then the best decisions for cooperation are risk-adverse (low sensitivity, high specificity). …”
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Ultrathin silica mesh protected Pt nanoparticles for hydrogen evolution reaction (HER) by Hung, Hsi Chien

“…Importantly, 0.2nm and 0.6nm SiO2-encapsulated electrocatalysts were found to have the best HER activities, with a Tafel slope of 58 and 57 mV dec−1 respectively. …”
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Microbial community-based protein production from wastewater for animal feed applications by Vethathirri, Ramanujam Srinivasan, Santillan, Ezequiel, Wuertz, Stefan

“…More research is needed to determine the composition of the microbial community best suited for SCP production, as well as its relationship with the microbial community in influent food-processing wastewaters. …”
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Use of magnesium-silicate-hydrate (M-S-H) cement mixes in 3D printing applications by Panda, Biranchi, Sonat, Cem, Yang, En-Hua, Tan, Ming Jen, Unluer, Cise

“…The assessment of rheological and mechanical properties, which led to an optimum mix that satisfied the printability criteria, was supported by microstructural characterization. The best-performing mix in terms of printability and mechanical performance was characterized via x-ray diffraction (XRD), thermogravimetric analysis/derivative thermogravimetry (TG/DTG) and field emission scanning electron microscopy (FESEM) with energy dispersive spectroscopy (EDS). …”
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Direct interspecies electron transfer (DIET) can be suppressed under ammonia-stressed condition - reevaluate the role of conductive materials by Yan, Wangwang, Mukherjee, Manisha, Zhou, Yan

“…However, upon ammonia stress, these materials behaved distinctively with the best methanogenic performance in ZVI group followed by Mag. …”
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Zeolitic imidazolate frameworks as capacitive deionization electrodes for water desalination and Cr(VI) adsorption: a molecular simulation study by Hong, Terence Zhi Xiang, Dahanayaka, Madhavi, Liu, Bo, Law, Adrian Wing-Keung, Zhou, Kun

“…Overall, this study uses molecular dynamics simulations to show that the metal atoms in ZIFs influence CDI desalination performance, which can help to screen ZIF materials for CDI applications. CdIF-1 performs best in the starting period for the four ZIFs tested.…”
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Highly sensitive transistor sensor for biochemical sensing and health monitoring applications: a review by Moudgil, Akshay, Leong, Wei Lin

“…Furthermore, organic and inorganic active material-based transistors are compared to find the best fit for specific target bio-detection and healthcare applications.…”
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