Molecular mechanisms relevant to the maintenance of locomotor control by Guo, F

“…Preferential degeneration of the <em>Penk</em>+ MSNs has been observed at early stage of Huntington disease (HD). …”

A separation-of-powers model for a trustworthy and open cloud computing ecosystem by Ruan, A

“…Trusted Cloud models have been proposed, which establish a Root-of-Trust inside the cloud and vouch for the trustworthiness of the cloud services. …”

Plasma trimethylamine N-oxide (TMAO): associations with cognition, neuroimaging, and dementia by Yaqub, A, Vojinovic, D, Vernooij, MW, Slagboom, PE, Ghanbari, M, Beekman, M, van der Grond, J, Hankemeier, T, van Duijn, CM, Ikram, MA, Ahmad, S

“…<p><b>Background</b></p> The gut-derived metabolite Trimethylamine N-oxide (TMAO) and its precursors - betaine, carnitine, choline, and deoxycarnitine – have been associated with an increased risk of cardiovascular disease, but their relation to cognition, neuroimaging markers, and dementia remains uncertain. …”

From the Andes to the coast: human mobility and diet in the Atacama desert during the late intermediate period (ad 900-1450) by Santana Sagredo, F

“…<p>The Late Intermediate Period in northern Chile has been strongly influenced by the mobility models of vertical archipelago and the gyratory mobility. …”

An aerodynamic investigation of a high-pressure turbine using rotor casing static pressure measurements at engine representative conditions with different tip designs, tip gaps, an... by Singh, D, Beard, PF, Cardwell, D, Staelens, V, Bahulekar, P, Stokes, M, Bather, S, Chana, K

“…Since the 1970s, extensive research has been undertaken to understand the over-tip leakage flow and develop mitigation strategies such as novel tip designs, to minimize the losses and heat load. …”

Prussian Blue analogue materials for magnetic and energy storage applications by Schart, M

“…Over the years since, many multifunctional properties have been discovered in its analogue materials. Members of the Prussian Blue analogue (PBA) family have shown promise for a wide variety of technological applications, ranging from energy and gas storage to catalysis and information storage. …”

The competing use of perfect and aorist tenses in Old Church Slavonic by MacRobert, C

“…In Old Church Slavonic the distribution of aorist and perfect tenses is problematic: it appears for the most part to be semantically motivated, but the distinction in meaning does not correspond exactly to what is found in modern Slavonic languages and therefore has to be inferred from Old Church Slavonic material. It has sometimes been suggested that in the second and third persons singular, which coincide formally in the aorist tense, variation between aorist and perfect forms may to some extent be correlated with explicitly marked distinctions of person in Greek, and may therefore be a side effect of translation; but such correlations are not regular, and the frequency of second person singular perfect forms is higher in some types of text than in others. …”

Sudden gains in internet cognitive therapy for social anxiety disorder in routine clinical practice by Yim, SH, Clark, DM, Salkovskis, PM, Thew, GR

“…<p><strong>Background:</strong>&nbsp;Sudden gains are large symptom improvements between consecutive therapy sessions. They have been shown to occur in randomised controlled trials of internet-delivered psychological interventions, but little is known about their occurrence when such treatments are delivered in routine clinical practice.…”

Pathway and network analysis of more than 2500 whole cancer genomes by Reyna, MA, Haan, D, Paczkowska, M, Verbeke, LPC, Vazquez, M, Kahraman, A, Pulido-Tamayo, S, Barenboim, J, Wadi, L, Dhingra, P, Shrestha, R, Getz, G, Lawrence, MS, Pedersen, JS, Rubin, MA, Wheeler, DA, Brunak, S, Izarzugaza, JMG, Khurana, E, Marchal, K, von Mering, C, Sahinalp, SC, Valencia, A, PCAWG Drivers and Functional Interpretation Working Group, Reimand, J, Stuart, JM, Raphael, BJ, PCAWG Consortium

“…However, non-coding cancer driver mutations are less well-characterized and only a handful of recurrent non-coding mutations, most notably TERT promoter mutations, have been reported. Here, as part of the ICGC/TCGA Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, which aggregated whole genome sequencing data from 2658 cancer across 38 tumor types, we perform multi-faceted pathway and network analyses of non-coding mutations across 2583 whole cancer genomes from 27 tumor types compiled by the ICGC/TCGA PCAWG project that was motivated by the success of pathway and network analyses in prioritizing rare mutations in protein-coding genes. …”

The anatomy of Westlothiana lizziae and a novel phylogenetic analysis of early amniotes by Igielman, B

“…<em>Westlothiana</em> has been recovered in various phylogenetic positions, including as a sister taxon to amniotes, to lepospondyls, or to a lepospondyl-amniote clade. …”

Brain markers of cumulative stress response and allostatic load in the ageing Whitehall II cohort by Zsoldos, E

“…Since 1985, rich socio-demographic, health and life-style measures have been acquired every 2-5 years. Eight hundred participants were randomly selected from the remaining 6,308 participants of Phase 11 for magnetic resonance imaging (MRI) and further examination in Oxford (2012-14).…”

Periodontal disease and serum uric acid levels in the absence of metabolic syndrome: is there a link? A study on a sample of Cameroonian adults by Nkeck, JR, Ndjoh, JJ, Meyo Mvondo, GF, Eko Ondoa, M, Takam, O, Mbouna, SFM, Tcheutchoua Nzokou, D, Tchuisseu-Kwangoua, LA, Momo, CBY, Ekouelkoum Ngoude, JX, Chemgne, MI, Ama Moor, VJ

“…Background: The relationship between serum uric acid level (SUA) and periodontal diseases (PD) is still controversial, and few studies have been carried out in population with no element of metabolic syndrome especially in sub-Saharan Africa. …”

International healthcare workers’ experiences and perceptions of the 2022 multi-country mpox outbreak by Apea, V, Titanji, BK, Dakin, FH, Hayes, R, Smuk, M, Kawu, H, Waters, L, Levy, I, Kuritzkes, DR, Gandhi, M, Rockstroh, J, Schechter, M, Holt, M, Palich, R, Cortes, CP, Nozza, S, Mussini, C, Calmy, A, Crabtree-Ramirez, BE, Blanco, JL, Bhagani, S, Dewsnap, C, Orkin, C, On Behalf of the Mpox SHARE-NET Writing Group

“…Less than 9% of HCWs in the region of the Caribbean, Central America and South America had been offered a vaccine as compared to almost one-third in the other regions. …”

Spontaneous ventricular tachyarrhythmias in β2-adrenoceptor transgenic mice in relation to cardiac interstitial fibrosis by Nguyen, M-N, Kiriazis, H, Ruggiero, D, Gao, X-M, Su, Y, Jian, A, Han, L-P, McMullen, JR, Du, X-J

“…Myocardial fibrosis is regarded as a pivotal proarrhythmic substrate, but there have been no comprehensive studies showing a correlation between the severity of fibrosis and ventricular tachyarrhythmias (VTAs). …”

Due regard obligations in the law of the sea convention by Fasia, EE

“…The content and function of these obligations have not been thoroughly and systematically studied and their application in practice can be problematic due to their indeterminate stipulation. …”

Genomic diversity and antimicrobial susceptibility of invasive Neisseria meningitidis in South Africa, 2016–2021 by Mikhari, RL, Meiring, S, de Gouveia, L, Chan, WY, Jolley, KA, Van Tyne, D, Harrison, LH, Marjuki, H, Ismail, A, Quan, V, Cohen, C, Walaza, S, von Gottberg, A, du Plessis, M

“…<p><strong>Background:</strong>&nbsp;Invasive meningococcal isolates in South Africa have in previous years (&lt;2008) been characterized by serogroup B, C, W, and Y lineages over time, with penicillin intermediate resistance (penⁱ) at 6%. …”

BRCA1 regulation of breast cancer cell motility by Hernandez Nuñez, ZE

“…Mutations in BRCA1 have been implicated in the increased risk of developing several cancers. …”

Evolution of an extracellular pathogen recognition mechanism in Solanaceae by Kourelis, J

“…Although many <em>R</em> genes have been identified, the molecular mechanism by which they function is only understood for a few.…”

Unfinished business: legalisation and implementation in business and human rights by Palmer, C

“…At the transnational level, the thesis discusses the Kimberley Process Certification Scheme (KPCS), the Extractive Industries Transparency Initiative (EITI), and the Voluntary Principles on Security and Human Rights (VPs), which have been selected as representative of the range of hybrid schemes increasingly developed by government and industry representatives to ameliorate the impact of TNCs on human rights.…”

Association of Indoleamine 2,3-dioxygenase (ido) activity with outcome after cardiac surgery in adult patients by Stieger, A, Huber, M, Yu, Z, Kessler, BM, Fischer, R, Andereggen, L, Kobel, B, Stueber, F, Luedi, MM, Filipovic, MG

“…Increased IDO activity has been observed in various diseases and is associated with worse clinical outcomes. …”