Somatic gene mutation patterns and burden influence outcomes with enasidenib in relapsed/refractory IDH2-mutated AML by Risueño, A, See, WL, Bluemmert, I, de Botton, S, DiNardo, CD, Fathi, AT, Schuh, AC, Montesinos, P, Vyas, P, Prebet, T, Gandhi, A, Hasan, M

“…We recently reported results from the phase 3 IDHENTIFY trial (NCT02577406) showing improved response rates and event-free survival with enasidenib monotherapy compared with conventional care regimens (CCR) in heavily pretreated, older patients with late-stage R/R AML bearing IDH2 mutations. Here we investigated the prognostic impact of mutational burden and different co-mutation patterns at study entry within the predominant IDH2 variant subclasses, IDH2-R140 and IDH2-R172. …”

Harnessing dimethyl ether with ultra-low-grade heat for scaling-resistant brine concentration and fractional crystallization by Foo, Zi Hao, Deshmukh, Akshay, Wilson, Aaron D., Lienhard, John H.

“…At a heat source temperature of 323 K and an interstage pressure of 0.489 bar, DME-driven SDWE achieves an optimal thermodynamic efficiency of 20.5 % and a projected specific cost of US$ 1.93 m−3. …”
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Dissecting the structure-compaction-performance relationship of thin-film composite polyamide membranes with different structure features by Zhao, Yali, Lai, Gwo Sung, Chong, Jeng Yi, Wang, Rong

“…TFC membrane with a PA layer of low protuberances or nodules and dense substrate showed excellent resistance against high pressure (50 bar), with only a slight irreversible decrease of 2.1–3.5% in water permeability when retested at 5 bar. …”
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Fractionation of catfish protein hydrolysates using ultrafiltration membrane by Novin, Donya

“…For 5 h hydrolysate, the highest transmission was achieved at pH 5.1, pressure of 2 bar, 0.15 M of NaCl and feed concentration of 1.5 mg/ml. …”
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Fisher vector faces in the wild by Simonyan, K, Parkhi, O, Vedaldi, A, Zisserman, A

“…Several recent papers on automatic face verification have significantly raised the performance bar by developing novel, specialised representations that outperform standard features such as SIFT for this problem. …”

How to Hold a Grudge : From Resentment to Contentment- the Power of Grudges to Transform Your Life / by Hannah, Sophie, 1971- author 649175

“…But aren't we supposed to just forgive, forget, and move on? Bearing a grudge is too negative, right? Wrong! Grudges, when held correctly, are an essential part of a healthy psychological diet. …”

Aminomethylation of enals through carbene and acid cooperative catalysis : concise access to β2-amino acids by Chi, Robin Yonggui, Xu, Jianfeng, Chen, Xingkuan, Wang, Ming, Zheng, Pengcheng, Song, Bao-An

“…This redox-neutral strategy is suitable for the scalable synthesis of enantiomerically enriched β2-amino acids bearing various substituents.…”
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Understanding systemic cooling poverty by Mazzone, A, De Cian, E, Falchetta, G, Jani, A, Mistry, M, Khosla, R

“…The poorest and most disadvantaged people, who contributed the least to global warming, are the ones bearing the most severe consequences of extreme heat because of their limited adaptive capacity. …”

Anti-fouling thin film composite (TFC) polyamide reverse osmosis (RO) membranes based on piezoelectric polyvinylidene fluoride (PVDF) substrates by Fu, Jia Shen

“…Based on such substrate and modified RO membrane fabrication protocol, RO membranes with higher permeability (~ 2 LMH/bar) and reasonable salt rejection (~98.9%) were obtained. …”
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High strain rate and elevated temperature compressive properties of magnesium alloy AZ31B by Myat, Thu.

“…Cylindrical specimens with same dimension but different fabricated directions (Transverse, Angular, Rolling and Normal) are used in compressive split Hopkinson bar test. Experiments are carried out under different temperature and strain rate. …”
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A Pilot Study to Evaluate the Relationships between Supine Proprioception Assessments and Upright Functional Mobility by Bellisle, Rachel F., Peters, Brian T., Oddsson, Lars, Wood, Scott J., Macaulay, Timothy R.

“…During the supine tasks, participants lay on the air-bearing sled with axial loading toward the tilt board. …”
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Search for Heavy Narrow Dilepton Resonances in Pp Collisions at √s = 7 TeV and √s = 8 TeV by Apyan, Aram, Bendavid, Joshua L., Busza, Wit, Butz, Erik M., Cali, Ivan Amos, Chan, M., Gomez-Ceballos, Guillelmo, Goncharov, Maxim, Kim, Y., Klute, Markus, Krajczar, Krisztian F., Ma, Teng, Nahn, Steven, Paus, Christoph M. E., Ralph, Duncan Kelley, Rudolph, Matthew Scott, Stephans, George S. F., Sung, Kevin Kai Hong, Velicanu, Dragos Alexandru, Wenger, Edward Allen, Wyslouch, Boleslaw, Yilmaz, Yetkin, Yoon, A. S., Zanetti, Marco, Bauer, Gerry P, Dutta, Valentina, Levin, Andrew Michael, Roland, Christof E, Stoeckli, Fabian, Luckey Jr, P David, Roland, Gunther M, Sumorok, Konstanty C, Wolf, Roger, Yang, Mingming, Wyslouch, Victoria

“…The analysis of the combined data sets excludes, at 95% confidence level, a Sequential Standard Model Z[' over SSM] resonance lighter than 2590 GeV, a superstring-inspired Z[' over ψ] lighter than 2260 GeV, and Kaluza–Klein gravitons lighter than 2390 (2030) GeV, assuming that the coupling parameter k/[bar over M][subscript Pl] is 0.10 (0.05). These are the most stringent limits to date.…”
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A self-rectifying unipolar HfOx based RRAM using doped germanium bottom electrode by Liu, W. J., Tran, Xuan Anh, Sun, Xiaowei, Yu, Hongyu

“…Owning to Schottky barrier between defect states in HfOx layer and n-Ge substrate, RRAM cells possess a self-rectifying behavior in LRS which eliminates the read-out errors induced by leakage current paths in cross-bar array structure. The demonstrated RRAM device shows high ON/OFF ratio (>5 × 102 @ 0.5 V), and its effective Schottky barrier height is also addressed. …”
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Stress analysis and stress intensity factor computation of DNV X65 pipes subjected to four point bending by Lee, Shaun Raphael Kwok Yuen

“…Proposed solution by Baik-Yamada for the shifting in neutral axis as a result of changing area of remaining load bearing ligament is also compared with finite element results. …”
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Fabrication and characterisation of kenaf fibre reinforced polyamide biocomposites for railway sleeper applications by ahmad, mukaddas, Abdul Aziz, Farah Nora Aznieta, Abdan, Khalina, Shafi, Ayu Rafiqah

“…The result further demonstrated that the load-bearing capacity peaked at TKF 40 wt.%, surpassing conventional wooden and concrete sleepers. …”
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Photo-modulable molecular transport junctions based on organometallic molecular wires by Meng, Fanben, Hervault, Yves-Marie, Norel, Lucie, Costuas, Karine, Dyck, Colin Van, Geskin, Victor, Cornil, Jérôme, Hng, Huey Hoon, Rigaut, Stéphane, Chen, Xiaodong

“…Photo-modulable molecular transport junctions are developed via on-wire lithography-fabricated nanogaps functionalized with a dithienylethene unit bearing two ruthenium fragments. A reversible and repeatable bi-state conductive switching upon alternate irradiation of UV and visible light can be distinctly observed. …”
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5G in Singapore : is the tide turning against Huawei? by Anuar, Amalina

“…Along with other countries also opting for non-Chinese 5G equipment, US Secretary of State Mike Pompeo declared this as evidence of Washington’s anti-Huawei campaign bearing fruit.…”
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Largest testicular tumour in South-East Asia: a case report by Aizat, S. I., Yusof, M. R., Lee, F. Y., Fahmy, O., Lee, C. K.S., Khairul Asri, M. G., Muhammad Nasrulazam, N., Vikinesan, V. K., Liyana Zayani, Y., Yusuf, M., Rashide, Y., Othman, A.

“…The patient seeks treatment at that point because he can't bear the embarrassment and fear of the treatment.…”
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Experimental investigation into load settlement characteristics of piled rafts in sand by Leong, Hazel Xueling.

“…Studies by many notable researchers in the years to come suggest that the most effective combinations of piles and raft happens when all the initial loading can be borne with the raft’s bearing capacity alone. The role of the piles was solely to reduce the excessive settlement experienced by the plain raft.…”
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Dense/porous bioceramic composites by Hu, Yifei

“…The pores were designed for bone ingrowth, whereas the graded pores and the dense cores were introduced for load bearing capability. For bone ingrowth, the porous structures must have a high porosity, a high interconnectivity, and a suitable pore size.…”
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