Roseburia intestinalis generated butyrate boosts anti-PD-1 efficacy in colorectal cancer by activating cytotoxic CD8⁺ T cells by Kang, Xing, Liu, Changan, Ding, Yanqiang, Ni, Yunbi, Ji, Fenfen, Lau, Harry Cheuk Hay, Jiang, Lanping, Sung, Joseph Jao Yiu, Wong, Sunny Hei, Yu, Jun

“…R. intestinalis or butyrate also significantly improved antiprogrammed cell death protein 1 (anti-PD-1) efficacy in mice bearing MSI-low CT26 tumours. Mechanistically, butyrate directly bound to toll-like receptor 5 (TLR5) receptor on CD8(+) T cells to induce its activity through activating nuclear factor kappa B (NF-& kappa;B) signalling. …”
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Patient-Centered Clinical Trial Design for Heart Failure Devices via Bayesian Decision Analysis by Chaudhuri, Shomesh E., Adamson, Phillip, Bruhn-Ding, Dean, Ben Chaouch, Zied, Gebben, David, Rincon-Gonzalez, Liliana, Liden, Barry, Reed, Shelby D., Saha, Anindita, Schaber, Daniel, Stein, Kenneth, Tarver, Michelle E., Lo, Andrew W.

“…This result reflects the willingness of heart failure patients to bear additional risks of the investigational device in exchange for its probable benefits. …”
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Towards Synergistic Understanding of Language Processing in Biological and Artificial Systems by Hosseini Asl, Eghbal

“…Over the past five years, artificial neural networks (ANNs) have achieved capabilities in the comprehension and production of language that are indistinguishable from those of humans, and their internal representations bear similarity to activity within the language network. …”
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中国民间故事的文化思考 ：以巧媳妇故事类型为例 = Cultural considerations in Chinese folktales : a case study of the Qiao Xi Fu story type by 蓝智欣 Lam, Zhi Xin

“…Being regarded lowly in the patriarchal clan system, women were obligated to conform to regimented rules and standards, on top of tending to family elders and fulfilling household duties. …”
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Food choice motivations and perceptions of healthy eating: a cross-sectional study among consumers in the UAE by Cheikh Ismail, L, Osaili, TM, Obaid, RS, Hashim, M, Ahmed, M, Al-Fayadh, F, Farah, A, Sad, H, Alghanem, H, Mohamad, MN, Saleh, ST, Al Daour, R, Masuadi, E, Stojanovska, L, Ali, HI, Al Dhaheri, AS

“…Females, younger adults, those with higher education levels, and those with normal BMI tended to have a slightly more positive perception of a healthy diet than their counterparts (p < 0.05). …”

Longitudinal patterns in smoking abstinence in trials of e-cigarettes for smoking cessation: secondary analysis of data from a systematic review, with meta-analyses by Hartmann-Boyce, J, Chan, J, Zhitnik, E, Pesola, F, Hajek, P, Lindson, N

“…Absolute continuous abstinence rates tended to decline over time, but varying slopes. For absolute point prevalence abstinence, three studies demonstrated a shallow decline over time, two a steep decline, and three the opposite—an increase in abstinence over time. …”

Experimental and numerical investigation of adhesively bonded kfrp/steel double strap joints incorporating eggshell powder-toughened epoxy adhesive by Chia Lia Yip, Chia Lia Yip, Sugiman Sugiman, Sugiman Sugiman, Desmond Chin, Desmond Chin, Ahmad, Hilton

“…For all the studied overlap lengths, the joint strength increased with the increase of the studied composite’s adherend thickness (1 - 4 mm); however, the overlap length reached the optimum at the overlap length of 80 mm, where beyond that overlap length, the joint strength tended to decrease. The maximum joint strength is achieved with a combination of 80 mm bond length and 4 mm KFRP thickness, resulting in a 226.5% enhancement compared to the baseline (composite thickness of 1 mm, with adhesive without filler). …”
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Tumor-targeted nano-assemblies for energy-blocking cocktail therapy in cancer by Chen, Manling, Liu, Yidu, Li, Yang, Liu, Xue

“…In studies with A549 tumor-bearing mice, the combination of low-dose 2-DG and metformin did not impede tumor growth, whereas 2-DG@MA-dots markedly decreased tumor volume, with the mean final tumor volume in the combination treatment group being approximately 89 times greater than that in the 2-DG@MA-dot group. …”
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Comparison of transport methodologies on near-field pollutant dispersion in urban environments using CFD by Tee, Clarence Wei Tat

“…The two methodologies are validated by simulating the dispersion phenomena for two test cases which largely bear resemblance to urban settings: a three-dimensional street canyon setup and the Mock Urban Setting Test (MUST) field experiment. …”
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Surface peptide functionalization of zeolitic imidazolate framework-8 for autonomous homing and enhanced delivery of chemotherapeutic agent to lung tumor cells by Nurul Akmarina, Mohd Abdul Kamal, Emilia, Abdulmalek, Sharida, Fakurazi, Cordova, Kyle E., Mohd Basyaruddin, Abdul Rahman

“…Chemotherapeutic agents used in treating certain cancer types operate in a non-selective manner tending to accumulate in normal, healthy tissue when high doses are used. …”
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Concurrent removal of Cu(II), Co(II) and Ni(II) from wastewater by nanostructured layered sodium vanadosilicate: competitive adsorption kinetics and mechanisms by Zhang, Xiaoyuan, Liu, Yu

“…It was further shown that with increasing the Cu2+ concentration from 5 mg/L to 200 mg/L in the ternary system, the respective adsorption efficiencies of Co2+ and Ni2+ tended to decrease from 97.4% to 26.0%, and 97.3 to 13.3% at an adsorbent dosage of 2.0 g/L. …”
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Development of the CHARIOT Research Register for the Prevention of Alzheimer’s Dementia and Other Late Onset Neurodegenerative Diseases by Larsen, Mark E., Curry, Lisa, Mastellos, Nikolaos, Robb, Catherine, Car, Josip, Middleton, Lefkos T.

“…Higher response rates tended to be associated with larger practices (r = 0.34), practices with a larger older population (r = 0.27), less socioeconomically disadvantaged practices (r = 0.68), and practices with a higher proportion of White patients (r = 0.82). …”
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Progressive collapse behaviour of precast concrete structures with advanced joints by Nguyen, Van Hung

“…Secondly, the pull-out test results highlighted a pivotal role of bearing force in anchorage strength of headed bars and strain behaviour. …”
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Design and investigation of block copolymers for dispersion of carbon nanotubes in polymer matrices by Liu, Chengyin

“…To further improve the tensile properties of the SWNTs/epoxy nanocomposites, we fabricated another series of PI-derived block copolymers via ring-opening polymerization initiated from hydroxyl-terminated polyimide of lactide and allyl-bearing 2-methyl-2-(allyloxycarbonyl)propylene carbonate) (MAC) to produce PLA-b-PI-b-PLA (TB1) and PMAC-b-PI-b-PMAC (TB2) which are polyester and poly(ester-carbonate)-derived, respectively. …”
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Synthesis of heavy cyanide analogs for the design of novel Prussian blue analogs by Yang, E

“…In order to provide illustrative points of comparison, analogous metal complexes bearing various strong-field ligands are also synthesized and analyzed using the same approach.…”

Three essays on behavioral and experimental economics by Li, Yupeng

“…We found that Singaporean senders tended to place more trust in responders with a Mainland Chinese accent than they did in responders with a Singaporean Chinese accent. …”
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Gate-level hardware priority resolvers for embedded systems by Balasubramanian, Padmanabhan, Maskell, Douglas Leslie

“…The estimated design metrics show that the modular approach tends to facilitate increasing reductions in delay and power-delay product (PDP) compared to the direct approach, especially as the size of the priority resolver increases. …”
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古典文学中的“戏妻”、“试妻”现象 = An analysis of "Husband Teasing wife" in classical Chinese literature by 郑慧萍 Tay, Hui Ping

“…At times when “Husband Teasing Wife” is being mentioned, Yuan Dynasty’s drama play Qiuhu Teased His Wife tends to appear in our minds. This drama depicts the story of Qiuhu returning home one day and failed to recognize his wife. …”
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Afiksasi nomina dalam bahasa Indonesia by Denistia, K, Rajeg, GPW

“…Our findings indicate that the affix ke-/-an tends to be derived from the adjective word, the affix per-/-an has an over-representation for noun-based words, and verbs have an over-representation as a base word for the affixes -an peN-, and peN-/-an. …”

Bacteria-mediated anti-cancer therapy by Bhave, Madhura Satish

“…However, IB significantly inhibited the growth of the tumors and improved the survival rate of immunocompetent CT26 tumor-bearing mice. Histological analysis showed that IB increased the necrotic area in HCT116 tumors. …”
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