Methane precipitation in ice giant atmospheres by Toledo, D, Rannou, P, Irwin, PG, de Batz de Trenquelléon, B, Roman, M, Apestigue, V, Arruego, I, Yela, M

“…However, no clear spectral signatures of such a cloud have been detected thus far in the spectra acquired from both planets.…”

The fragmented COVID-19 therapeutics research landscape: a living systematic review of clinical trial registrations evaluating priority pharmacological interventions by McLean, ARD, Rashan, S, Tran, L, Arena, L, Lawal, A, Maguire, BJ, Adele, S, Antonio, ES, Brack, M, Caldwell, F, Carrara, VI, Charles, R, Citarella, BW, Epie, TB, Feteh, VF, Kennon, K, Makuka, GJ, Ngu, R, Nwosu, A-P, Obiesie, S, Ogbonnaa-Njoku, C, Paul, P, Richmond, C, Singh-Phulgenda, S, Strudwick, S, Tyrrell, CSB, Stepniewska, K, Strub-Wourgaft, N, White, NJ, Guérin, PJ

“…<p><strong>Background:</strong> Many available medicines have been evaluated as potential repurposed treatments for coronavirus disease 2019 (COVID-19). …”

Characterising the metabolic functionality of the preterm neonatal gut microbiome prior to the onset of necrotising enterocolitis: a pilot study by Chapman, JA, Wroot, E, Brown, T, Beck, LC, Embleton, ND, Berrington, JE, Stewart, CJ

“…While gut microbiome compositions associated with NEC have been well studied, there is a lack of experimental work investigating microbiota functions and their associations with disease onset. …”

Personalised modelling of geographic movements in depression by Palmius, N

“…<p>It has been estimated that as many as 41% of individuals will experience depression at some point in their lives, a serious and debilitating mental illness. …”

Identifying falsified COVID-19 vaccines by analysing vaccine vial label and excipient profiles using MALDI-ToF mass spectrometry by Arman, BY, Clarke, R, Bharucha, T, Gomez Fernandez, L, Walsby-Tickle, J, Deats, M, Mosca, S, Lin, Q, Banerjee, S, Chunekar, S, Patil, K, Gairola, S, Dunachie, S, Merchant, H, Stokes, R, Kuwana, R, Maes, A, Charrier, J-P, Probert, F, Caillet, C, Matousek, P, McCullagh, J, Newton, P, Zitzmann, N, Gangadharan, B

“…However, these developments are associated with the risk of a surge of substandard and falsified (SF) vaccines, as illustrated by the 184 incidents with SF and diverted COVID-19 vaccines which have been reported during the pandemic in 48 countries, with a paucity of methods for their detection in supply chains. …”

Mobile health (mHealth) interventions for health promotion during the perinatal period in India: a scoping review by Small, Z, Thompson, SE, Sharma, A, Majumdar, S, Thout, SR, Praveen, D, Hirst, JE

“…Many mobile health (mHealth) interventions have been developed to improve maternal and infant health outcomes in India, however it is unclear how mHealth can best support women in this culturally and resource diverse setting. …”

An aerodynamic investigation of a high-pressure turbine using rotor casing static pressure measurements at engine representative conditions with different tip designs, tip gaps and... by Singh, D, Beard, PF, Cardwell, D, Staelens, V, Bahulekar, P, Stokes, M, Bather, S, Chana, KS

“…Since the 1970s, extensive research has been undertaken to understand the over-tip leakage flow, and develop mitigation strategies such as novel tip designs, to minimize the losses and heat load. …”

Study protocol for a pragmatic randomised controlled trial of comparing enhanced acceptance and commitment therapy plus (+) added to usual aftercare versus usual aftercare only, in... by Khan, I, Taylor, SJC, Robinson, C, Moschopoulou, E, McCrone, P, Bourke, L, Thaha, M, Bhui, K, Rosario, D, Ridge, D, Donovan, S, Korszun, A, Little, P, Morgan, A, Quentin, O, Roylance, R, White, P, Chalder, T

“…Discussion: To date, there have been no robust trials reporting both clinical and cost-effectiveness of an ACT based intervention for people with low QoL after curative cancer treatment in the UK. …”

Malaria as a cause of morbidity and mortality in children with homozygous sickle cell disease on the coast of Kenya by Komba, A, Makani, J, Sadarangani, M, Ajala-Agbo, T, Berkley, J, Newton, CRJC, Marsh, K, Williams, T

“…<p><strong>Background</p></strong>To date, it has been widely assumed that malaria is a common cause of morbidity and mortality in children with sickle cell disease (SCD) in malaria-endemic countries, and as a result, malarial prophylaxis is commonly recommended. …”

The development of electrochemical sensors based on the use of different forms of carbon materials by Chaisiwamongkhol, K

“…</p> <p>In this thesis, carbon based materials such as pyrolytic graphite; carbon nanotubes and carbon fibre have been used for a number of analytical and fundamental investigations. …”

Self-harm-related mental imagery: a content analysis study of imagery reported by young people referred to mental health services by Susi, K, Stewart, A, Knowles Bevis, R, Hawton, K

“…<p><strong>Background: </p></strong>Growing evidence suggests that self-harm-related mental imagery is involved in the transition from self-harm ideation to enactment. However, there has been little research on this important phenomenon in adolescent populations. …”

Implementing strategies to improve uptake of patient-reported outcome measures (PROMs) in gender-affirming care: a mixed-methods implementation study by Kamran, R, Jackman, L, Goodwin, C, Laws, A, Stepney, M, Harrison, C, Jain, A, Rodrigues, J

“…The PG-PROM-GAC has the potential to improve PROM implementation; however, its real-world effectiveness has not yet been investigated.</p> <p><strong>Objective</strong> Investigate effectiveness and fidelity of three implementation strategies from the PG-PROM-GAC in a real-world gender clinic setting.…”

Clouds and hazes in Saturn's troposphere and stratosphere by Merlet, CTC

“…At such pressure levels, thermochemical models predict the formation of condensed clouds made of ammonia and ammonium hydrosulphide ices, although none of these species has been spectrally detected so far. In addition, phosphine and ammonia are responsible for most of the gaseous absorption at these wavelengths. …”

Respiratory quality indices for automated monitoring of respiration from sensor data by Birrenkott, D

“…This is primarily because of the lack of a non-invasive, robust, automated method for estimating RR. It has previously been shown that the amplitude modulation (AM), frequency modulation (FM), and baseline wander (BW) of both the electrocardiogram (ECG) and photoplethysmogram (PPG) contain respiratory waveform information. …”

18F-labelling of new chemotypes for drug discovery by Khotavivattana, T

“…</p> <p>The Umemoto reagent has been extensively used for electrophilic trifluoromethylation of various functional groups. …”

BCC metals in extreme environments: modelling the structure and evolution of defects by Gilbert, M

“…Additionally, we compare the diffusion rates of these vacancy loops to their interstitial counterparts and find that, while interstitial loops are more mobile, the difference in mobility is not as significant as might have been expected. In part II we study screw dislocations, which, as the rate limiting carriers of plastic deformation, are significantly responsible for the strength of materials. …”

DEWP: deep expansion learning for wind power forecasting by Fan, W, Fu, Y, Zheng, S, Bian, J, Zhou, Y, Xiong, H

“…Wind power, as one of the largest renewable energy in the world, has been playing a more and more important role in supplying electricity. …”

Pneumococcal genomics and evolution by van Tonder, A

“…This analysis revealed that the majority of what had previously been described as serotype 6B pneumococci were in fact serotype 6E and serological assays demonstrated that vaccine-induced serotype 6B antibodies were able to kill serotype 6E pneumococci. …”

Developing generic clinical trial animated explainer videos in the UK: results of a survey and case study by Calvert, C, Barber, VS, Appelbe, D, Sprange, K, Nollett, C, Lugg-Widger, F, Tanner, S, Richards, DB

“…The top three topics were then turned into AEVs and have been made freely available for use. Method: A list of generic clinical trial topics which often need explaining to potential trial participants when they are approached to take part in research was developed. …”

Cost-utility analysis of molnupiravir plus usual care versus usual care alone as early treatment for community-based adults with COVID-19 and increased risk of adverse outcomes in... by Png, ME, Harris, V, Grabey, J, Hart, ND, Jani, BD, Butler, D, Carson-Stevens, A, Coates, M, Cureton, L, Dobson, M, Dorward, J, Evans, P, Francis, N, Gbinigie, OA, Hayward, G, Holmes, J, Hood, K, Khoo, S, Ahmed, H, Lown, M, McKenna, M, Mort, S, Nguyen-Van-Tam, J, Rahman, N, Richards, DB, Thomas, N, van Hecke, O, Hobbs, FR, Little, P, Yu, L-M, Butler, CC, Petrou, S

“…<p><strong>Background </p></strong>The cost-effectiveness of molnupiravir, an oral antiviral for early treatment of SARS-CoV-2, has not been established in vaccinated populations. <p><strong> Aim </p></strong>To evaluate the cost-effectiveness of molnupiravir relative to usual care alone among mainly vaccinated community-based people at higher risk of severe outcomes from COVID-19 over 6 months. …”