Dose escalation pre-clinical trial of novel DOK7-AAV in mouse model of DOK7 congenital myasthenia by Cossins, J, Kozma, I, Canzonetta, C, Hawkins, A, Beeson, D, Sepulveda, P, Dong, YY

“…Causative mutations have been identified in over 30 genes, including DOK7, a gene encoding a post-synaptic protein crucial in the formation and stabilization of the neuromuscular junction. …”

Securing reform? Post-election power sharing and security sector reform in Zimbabwe, Kenya, and Togo, 2006-2013 by Noyes, A

“…Traditionally used to end high-intensity civil wars, recently power sharing has increasingly been used to terminate an array of lower-intensity conflicts, such as election-related violence in Togo in 2006 and Kenya and Zimbabwe in 2008. …”

Strain rate, temperature, and their coupled effects on the deformation process of four polycarbonates and a short glass fibre reinforced polycarbonate composite by Song, P

“…<p>Polycarbonate is a typical glassy thermoplastic polymer, which has been widely used in engineering applications because of its ductility, transparency and impact resistance. …”

Outbreaks of COVID-19 in a tuberculosis treatment sanatorium on the Thailand-Myanmar border: a retrospective cohort analysis by Aung, HKK, Swe, LL, Saito, M, Lesseps, S, Janurian, N, Tun, WPP, Maung Maung, B, Than, A, Watthanaworawit, W, Kaewphanderm, N, Gornsawun, G, Pyae Phyo, A, Nosten, F

“…<p><strong>Background</strong><br> Tuberculosis (TB) is a chronic condition, with overlapping symptoms to those of coronavirus disease 2019 (COVID-19). There has been inconsistent evidence on whether TB is a predisposing factor for developing severe COVID-19. …”

Social inclusion in the legal profession: a study of the solicitor apprenticeship by Polding, E

“…In addition, as participating apprentices were often school leavers rather than graduates, there were few expectations in relation to professional experience that might have been expected of more conventional trainee solicitor recruits. …”

Towards understanding genome regulation via high-resolution analysis of chromatin accessibility by Dai, L

“…<p>Next generation sequencing has been used to in functional genomics to rep- resent specific aspects of chromatin structure, DNA-protein interactions and the epigenome, enriching the knowledge of the non-coding genome which plays significantly roles in gene regulation but is vaguely understood. …”

The COVID guidelines India project: a rapid living evidence synthesis during a pandemic in a LMIC setting by Singh, B, Alexander, H, Tharyan, P, Mathew, JL, Covid Management Guidelines India Group, Garner, P, Rupali, P, Core Committee, Rupali, P, Ryan, H, Steering Committee, Methodology Committee, External Advisory Panel, Expert Working Group – Antiviral, Expert Working Group – Anti-inflammatory, Expert Working Group - Antibody, Expert Working Group - Anticoagulation, Expert Working Group - Respiratory support, Expert Working Group - Other Supportive Therapy, Evidence Synthesis Team, Dissemination Team

“…</p> <br> <p><strong>Results:</strong> Since May 2021, a total of 20 guidelines have been developed spanning pharmacological, respiratory and other supportive interventions for management of COVID-19, with over 83,600 unique page views up to December 2023. …”

Sensitive detection of PIK3CA Exon 20 H1047R breast cancer based on lowcost intercalary dye SYBR Green I real-time qPCR assay by Desriani, Azamris, Rustamadji, Primariadewi, Abna, Inherni Marti, Ibadurrahman, Irsyad, Fuad, Asrul Muhammad, Nurdiani, Dini, Yuliawati, Yuliawati, Herawati, Neng, Fitria, Najmiatul, Warisman, Muhammad Ali, Utami, Nuruliawaty

“…Detection of PIK3CA/H1047R mutation has also been reported for molecular diagnosis and therapeutic application. …”
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Ultrasonic-assisted extraction of phenolic compound from harumanis mango leaves (Mangifera indica) using green Natural Deep Eutectic Solvents (NADESs) by Ahmad Mukhlis Abdul Rahman, Ryan Vitthaya Peron, Amirul Ridzuan Abu Bakar, Muhammad Syaffiq Syazwan Jaafar, Qian, Yee Ang, Mohd Asraf Mohd Zainudin, Nik Muhammad Azhar Nik Daud, Ahmad Anas Nagoor Gunny, Nurul Husna Khairuddin

“…There is limited information on green extraction from Harumanis mango leaves, and NADESs have not been used for this purpose. This study aims to evaluate the green extraction of phenolic compounds from Harumanis mango leaves using five NADESs systems, assess the phytochemical composition, and test their antimicrobial potential. …”
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Ethnic differences in knowledge, attitudes, and practices related to dietary salt intake and association with hypertension in Malaysia: a multi-centre cross-sectional study by Chia, Yook Chin, Ching, Siew Mooi, Chew, Ming Tsuey, Devaraj, Navin Kumar, Oui, Jethro Ee Keat, Lim, Hooi Min, Chew, Bee Nah, Mohamed, Mohazmi, Ooi, Pei Boon, Cheng, Maong Hui, Beh, Hooi Chin, Chung, Felicia Fei-Lei

“…The association between high salt intake and elevated blood pressure levels has been well-documented. However, studies on how effectively this knowledge translates into actionable practices, particularly across different ethnic groups, remain limited. …”

Dysfunctional cardiac energy transduction, mitochondrial oxidative stress, oncogenic and apoptotic signaling in DiNP-induced asthma in murine model by Kehinde, Samuel Abiodun, Olajide, Abosede Temitope, Fatokun, Tolulope Peter, Faroud, Dalia, Hadi, Najah R., Elgazzar, Ahmed M., James, Adewale Segun, Ashour, Mohamed H. Mazhar

“…Diisononyl phthalate (DiNP) has been associated with the development of allergies, asthma, and allergic airway inflammation. …”
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Mesh quality improvement by re-triangulation surface meshes on 3-dimensional CAD model of a human wrist joint by Leong, Mun Teik

“…With the recent advances computing technologies nowadays, reverse engineering is rapidly developing and has been strongly established many years in biomedical industry. …”
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Recent use of AB mix nutrients for urban farming in Malaysia: a mini review by Sanusi, Nur Dinie Syahirah, Ros, Fadhlina Che, Demon, Siti Zulaikha Ngah, Ismail, Ismayadi, Hamadneh, Imad

“…Therefore, a survey has been carried out on several local agriculture entrepreneurs to compare their usage of AB mix nutrients for chili plants and the results revealed that majority of the respondents comply with the established guidelines. …”
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Differentiation of lard from other fat in pastry products using fourier transform infrared spectroscopy combined multivariate analysis by Mohamed Rani, Wan Siti Farizan

“…Since edible oils spectra seems similar through visual inspection,chemometrics analysis of partial least square (PLS)-second derivate and discriminant (DA) analysis have been proposed to quantify and classify the presence of lard. …”
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Inference for autoregressive and moving average models with extreme value distribution via simulation study by Samuel, Bako Sunday

“…Time series analysis has emerged as one of the most important statistical discipline and it has been applied in different fields over the years. …”
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Improving purity of bio-based crotonic acid by Farid, Nur Falia Shazana Manja

“…Recently, bio-based crotonic acid production has been introduced through pyrolysis of bacterial polyhydroxybutyrate (P(3HB)) inclusions, however the purity of the crotonic acid produced was low (54%). …”
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Construction and characterization of a Lactococcus lactis in-trans surface display system harboring murine glycosylated tyrosinase related protein-2 by Kalyanasundram, Jeevanathan

“…This presents a major disadvantage in surface display system particularly when glycosylation has been recently identified to significantly enhance epitope presentation. …”
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Self-healing framework for service level agreement monitoring and violation reacting in cloud computing by Mosallanejad, Ahmad

“…The proposed system has also been executed in real environment for validation purposes.…”
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Apoptotic-related signalling pathways in mcf-7 cells treated with ethyl acetate extract of dillenia suffruticosa, and isolation of its major compounds by Yin, Sim Tor

“…Dillenia suffruticosa (Griff) Martelli that belongs to the family Dilleniaceae has been traditionally used to treat cancerous growth. …”
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Extraction, purification and characterization of amylase enzyme from white pitaya (Hylocereus undatus (Haworth) britton & rose) peel using aqueous two- phase system by Shad, Zahra

“…Although it consists about 33% of whole fruit by weight and possesses valuable enzymes such as amylase, it is not being presently used commercially and is considered as a waste. It could have been efficiently used for commercial and economical production of natural enzymes. …”
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