Assessing long-term effectiveness and cost-effectiveness of statin therapy in the UK: a modelling study using individual participant datasets by Mihaylova, B, Wu, R, Zhou, J, Williams, C, Schlackow, I, Emberson, J, Reith, C, Keech, A, Robson, J, Parnell, R, Armitage, J, Gray, A, Simes, J, Baigent, C

“…UK primary and hospital care data informed healthcare costs (2020/2021 UK£); £1.22 standard or £1.68 higher intensity generic statin therapy per 28 tablets; and Health Survey for England data informed health-related quality of life. …”

An omics-based machine learning approach to predict diabetes progression: a RHAPSODY study by Slieker, Roderick C., Münch, Magnus, Donnelly, Louise A., Bouland, Gerard A., Dragan, Iulian, Kuznetsov, Dmitry, Elders, Petra J. M., Rutter, Guy A., Ibberson, Mark, Pearson, Ewan R., Hart, Leen M. 't, van de Wiel, Mark A., Beulens, Joline W. J.

“…Results: Of the 585 individuals from the Hoorn Diabetes Care System (DCS) cohort, 69 required insulin during follow-up (1.0–11.4 years); of the 571 individuals in the Genetics of Diabetes Audit and Research in Tayside Scotland (GoDARTS) cohort, 175 required insulin during follow-up (0.3–11.8 years). …”
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Strategies to modulate Amorphous Oxide Semiconductor properties for low temperature transparent transistors by Kulkarni, Mohit Rameshchandra

“…The prospect of athermal annealing with the inclusion of a reducing oxide layer carefully chosen from the Ellingham diagram used as an overlayer on the semiconducting oxide layer was also explored. …”
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Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes by McAllan, Liam, Baranasic, Damir, Villicaña, Sergio, Brown, Scarlett, Zhang, Weihua, Lehne, Benjamin, Adamo, Marco, Jenkinson, Andrew, Elkalaawy, Mohamed, Mohammadi, Borzoueh, Hashemi, Majid, Fernandes, Nadia, Lambie, Nathalie, Williams, Richard, Christiansen, Colette, Yang, Youwen, Zudina, Liudmila, Lagou, Vasiliki, Tan, Sili, Castillo-Fernandez, Juan, King, James W. D., Soong, Richie, Elliott, Paul, Scott, James, Prokopenko, Inga, Cebola, Inês, Loh, Marie, Lenhard, Boris, Batterham, Rachel L., Bell, Jordana T., Chambers, John Campbell, Kooner, Jaspal S., Scott, William R.

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Towards electrically injected colloidal semiconductor lasers by Thung, Yi Tian

“…Overcoming this requires careful selection of nanocrystals as gain media, a resonant optical cavity supporting low lasing thresholds and high optical gain, and an architecture suitable for high electrical injection currents to achieve population inversion for lasing. …”
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Blood-stage malaria vaccine candidate RH5.1/Matrix-M in healthy Tanzanian adults and children; an open-label, non-randomised, first-in-human, single-centre, phase 1b trial by Silk, SE, Kalinga, WF, Salkeld, J, Mtaka, IM, Ahmed, S, Milando, F, Diouf, A, Bundi, CK, Balige, N, Hassan, O, Mkindi, CG, Rwezaula, S, Athumani, T, Mswata, S, Lilolime, NS, Simon, B, Msami, H, Mohamed, M, David, DM, Mohammed, L, Nyaulingo, G, Mwalimu, B, Juma, O, Mwamlima, TG, Sasamalo, IA, Mkumbange, RP, Kamage, JJ, Barrett, JR, King, LDW, Hou, MM, Pulido, D, Carnrot, C, Lawrie, AM, Cowan, RE, Nugent, FL, Roberts, R, Cho, J-S, Long, CA, Nielsen, CM, Miura, K, Draper, SJ, Olotu, AI, Minassian, AM

“…</p> <br> <p><strong>Funding:</strong> The European and Developing Countries Clinical Trials Partnership; the UK Medical Research Council; the UK Department for International Development; the National Institute for Health and Care Research Oxford Biomedical Research Centre; the Division of Intramural Research, National Institute of Allergy and Infectious Diseases; the US Agency for International Development; and the Wellcome Trust.…”

Electronic cigarettes for smoking cessation by Lindson, N, Butler, AR, McRobbie, H, Bullen, C, Hajek, P, Wu, AD, Begh, R, Theodoulou, A, Notley, C, Rigotti, NA, Turner, T, Livingstone-Banks, J, Morris, T, Hartmann-Boyce, J

“…Evidence comparing nicotine EC with usual care or no treatment also suggests benefit, but is less certain due to risk of bias inherent in the study design. …”

Interventions for smoking cessation in hospitalised patients by Streck, JM, Rigotti, NA, Livingstone-Banks, J, Tindle, HA, Clair, C, Munafò, MR, Sterling-Maisel, C, Hartmann-Boyce, J

“…<p><b>Objectives</b></p> To assess the effects of any type of smoking cessation programme for patients admitted to an acute care hospital. <p><b>Search methods</b></p> We used standard, extensive Cochrane search methods. …”

Electronic cigarettes for smoking cessation by Lindson, N, Butler, AR, McRobbie, H, Bullen, C, Hajek, P, Begh, R, Theodoulou, A, Notley, C, Rigotti, NA, Turner, T, Livingstone-Banks, J, Morris, T, Hartmann-Boyce, J

“…Evidence comparing nicotine EC with usual care/no treatment also suggests benefit, but is less certain due to risk of bias inherent in the study design. …”

Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 by Bhattacharjee, NV, Schumacher, AE, Aali, A, Almidani, O, Bandyopadhyay, S, Graham, SM, Lacey, BWH, Maude, RJ, Runghien, T, Rodriguez, JAB

“…Estimates and projections of fertility are necessary to inform policies involving resource and health-care needs, labour supply, education, gender equality, and family planning and support. …”