Infections diagnosed in children and young people screened for malaria in UK emergency departments: a retrospective multi-centre study by Bird, C, Hayward, GN, Turner, PJ, Wasala, D, Merrick, V, Lyttle, MD, Mullen, N, Fanshawe, TR

“…Half (50.0%) had infections common in both tropical and non-tropical settings such as viral upper respiratory tract infection (URTI); 21.0% of infections were coded as tropical if gastro-enteritis is included, with a total of 4.2% (60) cases of malaria. CYP diagnosed with malaria were 7.44 times more likely to have arrived from sub-Saharan Africa than from South Asia (OR 7.44, 3.78–16.41).…”

Development and implementation of a 3d-HDR brachytherapy program for cervical cancer in a sub-Saharan African centre by Joseph, A, Balogun, O, Adegboyega, B, Salako, O, Irabor, OC, Ajose, A, Adeneye, S, Alabi, A, Ohazurike, E, Ogamba, CF, Oladipo, A, Fagbemide, O, Habeebu, M, Puthoff, D, Onitilo, A, Ngwa, W, Nwachukwu, C

“…</p> <p><strong>RESULTS:&nbsp;</strong>The 3D-HDR brachytherapy program was successfully implemented, with five cases treated in the first 2 months despite challenges such as high equipment costs, expertise and proficiency needs, and source replacement delays. …”

15th-century printed Italian editions of Aesopian texts by Malaspina, M

“…</p> <p>The <em>Conclusions</em> focus on the originality of certain texts created specifically for the press, on the people who played an important role in the composition and printing of Aesopian texts, on the identification of new lines of transmission in print, on the distinction and analysis of different iconographic lines of descent in the illustrated editions, and on the discovery of noteworthy cases of provenance evidence, which suggest how the consumption of Aesopian Italian incunables transversely engaged people at different social and cultural levels.…”

Heterogeneity in definitions of surgical site infection after cranial surgery limits the validity of research findings in neurosurgery: a systematic review by Majidi, N, Sivakumar, A, Vogt, A, Ranganathan, S, Ashkan, K, Price, SJ, Lee, KS

“…Subspecialties included were neuro-oncology (n = 103,19.8%), neurotrauma (n = 92,17.7%), paediatric neurosurgery (n = 56,10.8%), functional neurosurgery (n = 52,10.0%), neurovascular (n = 38,7.3%), skull base (n = 37,7.1%), cerebrospinal fluid dynamics (n = 11,2.1%), and general neurosurgical cases (n = 149,28.7%). A hundred and sixty-nine (32.6%) studies reported SSI-CRAN definitions. …”

Analysis of incidence of motor neuron disease in England 1998–2019: use of three linked datasets by Burchardt, JM, Mei, XW, Ranger, T, McDermott, CJ, Radunovic, A, Coupland, C, Hippisley-Cox, J

“…The QResearch and linked Hospital Episode Statistics and Death register databases were searched from 1998 to 2019 for cases of MND, and incidence calculated from 16.8 million adults and 112 million adult years of data. …”

‘An unimaginable challenge’: a cross-cultural qualitative study of ethics and decision-making around tracheostomy ventilation in patients with amyotrophic lateral sclerosis by Ozeki-Hayashi, R, Wilkinson, D

“…We used three hypothetical cases to explore decision-making. Conversations were transcribed and thematically analyzed. …”

A simple approach to improve recording of concerns about child maltreatment in primary care records: developing a quality improvement intervention by Woodman, J, Allister, J, Rafi, I, de Lusignan, S, Belsey, J, Petersen, I, Gilbert, R

“…As failure to use codes makes it impossible to search or audit these cases, an approach designed to be simple and feasible to implement in UK general practice was recommended.…”

Understanding the consequences of education inequality on cardiovascular disease: mendelian randomisation study by Carter, AR, Gill, D, Davies, NM, Taylor, AE, Tillmann, T, Vaucher, J, Wootton, RE, Munafò, MR, Hemani, G, Malik, R, Seshadri, S, Woo, D, Burgess, S, Davey Smith, G, Holmes, MV, Tzoulaki, I, Howe, LD, Dehghan, A

“…Conclusions: BMI, systolic blood pressure, and smoking behaviour mediate a substantial proportion of the protective effect of education on the risk of cardiovascular outcomes and intervening on these would lead to reductions in cases of cardiovascular disease attributable to lower levels of education. …”

Heterotic string compactification and quiver gauge theory on toric geometry by Sun, C

“…After explicitly computing the Diophantine equation of five block cases, we use this structure to re-organize the result in a form that can be applied to arbitrary block numbers. …”

Genomic diversity and antimicrobial susceptibility of invasive Neisseria meningitidis in South Africa, 2016–2021 by Mikhari, RL, Meiring, S, de Gouveia, L, Chan, WY, Jolley, KA, Van Tyne, D, Harrison, LH, Marjuki, H, Ismail, A, Quan, V, Cohen, C, Walaza, S, von Gottberg, A, du Plessis, M

“…</p> <p><strong>Results:</strong>&nbsp;Of 585 IMD cases reported during the study period, culture and PCR-based capsular group was determined for 477/585 (82%); and 241/477 (51%) were sequenced. …”

ECG analysis of ventricular fibrillation dynamics reflects ischaemic progression subject to variability in patient anatomy and electrode location by Martinez-Navarro, H, Bertrand, A, Doste, R, Smith, H, Tomek, J, Ristagno, G, Oliveira, RS, Weber dos Santos, R, Pandit, SV, Rodriguez, B

“…Ischaemia in the remote myocardium modulated fibrillation dynamics. Cases presenting a mildly ischaemic remote myocardium yielded sustained VF, enabled by the high proliferation of phase singularities (PS, 11–22) causing remarkably disorganised activation patterns. …”

Episcopacy and parochialism in early South African Anglicanism: Bishop Robert Gray and the antecedent churches of the Cape Colony, 1806-72 by Bester, M

“…It explores the nature of opposition that Gray’s episcopacy faced from the fourteen independent worshipping congregations established privately or by the colonial state between 1806 and 1847, and how he brought these disputes to resolution, or, in some cases, failed to do so.</p> <p>Anglicanism in the Cape Colony prior to Gray was a state-dominated minority denomination established under a system of colonial ordinances. …”

The molecular pathogenesis of FUS mutations in amyotrophic lateral sclerosis using in vivo and in vitro models by Kent, L

“…Fused in sarcoma (FUS) is an RNA binding protein, and mutations in the FUS gene are responsible for approximately 4% of familial and &amp;LT;1% of sporadic ALS cases. This work uses <em>in vitro</em> and <em>in vivo</em> models to examine the cellular effects of FUS mutations and the potential mechanisms of motor neuron toxicity.…”

First-in-man study of the PSMA Minibody IR800-IAB2M for molecularly targeted intraoperative fluorescence guidance during radical prostatectomy by Hamdy, FC, Lamb, AD, Tullis, IDC, Verrill, C, Rombach, I, Rao, SR, Colling, R, Barber, PR, Volpi, D, Barbera-Martin, L, Lopez, JF, Omer, A, Hewitt, A, Lovell, S, Niederer, J, Lambert, A, Snoeck, J, Thomson, C, Leslie, T, Bryant, RJ, Mascioni, A, Jia, F, Torgov, M, Wilson, I, Gudas, J, Wu, AM, Olafsen, T, Vojnovic, B

“…<p><strong> Results</strong></p> Twenty-three patients were evaluated to optimise both the dose of the reagent and the interval between injection and surgery and secure the best possible specificity of fluorescence images. Six cases are presented in detail as exemplars. Overall sensitivity and specificity in detecting non-lymph-node extra-prostatic cancer tissue were 100% and 65%, and 64% and 64% respectively for lymph node positivity. …”

Development and evaluation of a polygenic risk score for lung cancer in never-smoking women: a large-scale prospective Chinese cohort study by Wei, X, Sun, D, Gao, J, Zhang, J, Zhu, M, Yu, C, Ma, Z, Fu, Y, Ji, C, Pei, P, Yang, L, Millwood, IY, Walters, RG, Chen, Y, Du, H, Jin, G, Chen, Z, Hu, Z, Li, L, Shen, H, Lv, J, Ma, H

“…We first performed a large GWAS meta-analysis (8595 cases and 8275 controls) to systematically identify the susceptibility loci for lung cancer in never-smoking Asian women and then generated a PRS using GWAS datasets. …”

The Effect Of Blended Learning And critical Thinking On Tertiary EFL Argumentative Writing In China by Wang, Yuling

“…As no single standard for blending exists, more research reports on blended learning cases are needed. This study aims to examine the effect of blended learning and critical thinking on EFL students’ performance in argumentative writing, and the factors that influence students’ argumentative writing performance in a blended learning environment were explored in the current study. …”
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A hole accelerator for InGaN/GaN light-emitting diodes by Zhang, Zi-Hui, Liu, Wei, Tan, Swee Tiam, Zhang, Yiping, Ji, Yun, Wang, Liancheng, Zhu, Binbin, Lu, Shunpeng, Zhang, Xueliang, Hasanov, Namig, Sun, Xiao Wei, Demir, Hilmi Volkan

“…The low hole mobility makes the holes less energetic, which hinders the hole injection into the multiple quantum wells (MQWs) especially when a p-type AlGaN electron blocking layer (EBL) is adopted. …”
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GPS/odometry/map fusion for vehicle positioning using potential function by Jiang, Rui, Yang, Shuai, Ge, Shuzhi Sam, Liu, Xiaomei, Wang, Han, Lee, Tong Heng

“…Distinguished from conventional sensor fusion methods, two types of potential functions (i.e. potential wells and potential trenches) are proposed to represent measurements and constraints, respectively. …”
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Inclusive and differential cross section measurements of t t ¯ b b ¯ production in the lepton+jets channel at √𝑠 = 13 TeV by Hayrapetyan, A., Tumasyan, A., Adam, W., Andrejkovic, J. W., Bergauer, T., Chatterjee, S., Damanakis, K., Dragicevic, M., Escalante Del Valle, A., Hussain, P. S., Jeitler, M., Krammer, N., Liko, D., Mikulec, I., Schieck, J., Schöfbeck, R., Schwarz, D.

“…The inclusive cross section measurements of this process in the fiducial phase space regions are the most precise to date. In most cases, the measured inclusive cross sections exceed the predictions with the chosen generator settings. …”
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Assessing the origin of and potential for international spread of Chikungunya virus from the Caribbean by Khan, Kamran, Bogoch, Isaac, Brownstein, John S., Miniota, Jennifer, Nicolucci, Adrian, Hu, Wei, Nsoesie, Elaine O., Cetron, Martin, Creatore, Maria Isabella, German, Matthew, Wilder-Smith, Annelies

“…Methods: We analyzed historical data on airline travelers departing areas of the Caribbean and South America, where locally acquired cases of chikungunya have been confirmed as of May 12th, 2014. …”
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