Database and Application Programming Interface Development for Rotational Spectroscopy by Cheung, Jasmine So Yee

“…A database of spectroscopic data serves as the foundation of the automation pipeline for assigning spectral lines to species. While there are existing databases available for use, we developed our custom database, named SAAGAdb, and an application programming interface (API) to access the database to fulfill the needs of SAAGA. …”
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Cytotoxic triosmium carbonyl clusters : a structure-activity relationship study by Top, Siden, Vessières, Anne, Leong, Weng Kee, Lee, Shirley Hui Zhi

“…In vitro evaluation of these new compounds showed that some are selectively active against estrogen receptor (ER)-independent MDA-MB-231 breast cancer cell lines relative to ER-dependent MCF-7 breast cancer cells, suggesting that the compounds have a different biological target specific to MDA-MB-231 cells. …”
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An iGlu receptor antagonist and its simultaneous use with an anticancer drug for cancer therapy by Luo, Zhong, Li, Peizhou, Tan, Si Yu, Ang, Chung Yen, Nguyen, Kim Truc, Zhao, Yanli

“…In vitro studies on B16F10 and NIH3T3 cell lines revealed that the iGlu receptor antagonist L1 exhibited therapeutic as well as targeting effects. …”
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Extensive promoter-centered chromatin interactions provide a topological basis for transcription regulation by Li, Guoliang, Ruan, Xiaoan, Auerbach, Raymond K., Sandhu, Kuljeet Singh, Zheng, Meizhen, Wang, Ping, Poh, Huay Mei, Goh, Yufen, Lim, Joanne, Zhang, Jingyao, Sim, Hui Shan, Peh, Su Qin, Mulawadi, Fabianus Hendriyan, Ong, Chin Thing, Orlov, Yuriy L., Hong, Shuzhen, Zhang, Zhizhuo, Landt, Steve, Raha, Debasish, Euskirchen, Ghia, Wei, Chia-Lin, Ge, Weihong, Wang, Huaien, Davis, Carrie, Fisher-Aylor, Katherine I., Mortazavi, Ali, Gerstein, Mark, Gingeras, Thomas, Wold, Barbara, Sun, Yi, Cheung, Edwin, Liu, Edison, Sung, Wing-Kin, Snyder, Michael, Ruan, Yijun, Fullwood, Melissa Jane

“…Comparative analyses of different cell lines showed that cell-specific chromatin interactions could provide structural frameworks for cell-specific transcription, and suggested significant enrichment of enhancer-promoter interactions for cell-specific functions. …”
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Investigating the content and function of stress-induced extracellular vesicles in colorectal cancer by Mason, J

“…Therefore, my DPhil focussed on investigating the potential pro-tumorigenic properties of these “switched” EVs in CRC cell lines in vitro and also assessing the composition of EVs in CRC patient plasma.…”

Neuroprotective effect of tocotrienol-rich fraction and a-tocopherol of vitamin E against glutamate toxicity in neuronal cells and astrocytes by Selvaraju, Thilaga Rati

“…In this study, the effects of vitamin E when supplemented before (pre-treatment) and after (post-treatment) glutamate insult were elucidated in neuronal and astrocyte cell lines. The neuroprotective effect of TRF and α-TCP were investigated. …”
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Design and investigation of block copolymers for dispersion of carbon nanotubes in polymer matrices by Liu, Chengyin

“…To further improve the tensile properties of the SWNTs/epoxy nanocomposites, we fabricated another series of PI-derived block copolymers via ring-opening polymerization initiated from hydroxyl-terminated polyimide of lactide and allyl-bearing 2-methyl-2-(allyloxycarbonyl)propylene carbonate) (MAC) to produce PLA-b-PI-b-PLA (TB1) and PMAC-b-PI-b-PMAC (TB2) which are polyester and poly(ester-carbonate)-derived, respectively. …”
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Structure and functions of a metallo-beta-lactamase- like hypothetical protein bleg1_2437 from alkali-tolerant soil bacterium Bacillus lehensis G1 by Tan, Soo Huei

“…However, the emergence of antibiotic resistance mechanism among pathogenic bacteria has downsized the efficacy of antibiotics via the production metallo-β-lactamase (MBL) which enables pathogens to destroy the β- lactam ring of β-lactam antibiotics. Although MBL is not ubiquitously found in all pathogenic bacteria, its presence is a public health concern. …”
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Serial interconnections of 1-contracting and 2-contracting systems by Ofir, Ron, Margaliot, Michael, Levron, Yoash, Slotine, Jean-Jacques

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Assessing the financial performance of container shipping companies by Shen, Wanling.

“…Five companies were shortlisted from the top 30 container shipping lines, where trends and changes in five selected indicators were analyzed over a specified timeframe before and after integration. …”
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Targeted therapy to gastric cancer by Hou, Qian.

“…In this study, 17 gastric cancer cell lines were used to screen a library of 60 small molecule inhibitors and chemotherapy drugs for discovery of potential therapeutic agent by methyl thiazole tetrazolium (MTT) assays. 8 effective drugs which include Docetaxel, Paclitaxel, 17-DMAG, Bortezomib, Calyculin A, Okadaic acid, Staurosporine and Bafilomycin A1 were identified and subject to further characterization by IC50 calculation, cell migration assay, morphology study and cell cycle analysis by FACS. …”
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Reconfigurable antennas for GSM and WLAN applications by IHD Mavidu Nipunath Iddagoda

“…A prototype antenna was fabricated with commercially available diodes used for switching between the two frequency bands. DC biasing lines were drawn from the top surfaces of the nested antenna. …”
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Effects of hemodynamic shear stress on circulating tumor cells by How, Yunhan

“…MDA-231-C3 was circulated and recovered repeatedly to obtain a series of flow-selected breast cancer cell lines (231-S1 to 231-S6). The effect of fluid shear stress on CTC survival was studied by quantifying the cell viability and level of apoptosis at 0-hr, 12-hr and 24-hr time points of circulation. …”
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Impact of BREXIT on key stakeholders of the maritime industry in Asia by Eng, Esther Cai Yun

“…These will impact the stakeholders, which are mainly shipping lines, port operators, ship owners, seafarers and maritime professionals. …”
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YY1 binding is a gene-intrinsic barrier to Xist-mediated gene silencing by Bowness, JS, Almeida, M, Nesterova, T, Brockdorff, N

“…In this study, we examine mouse embryonic stem cell lines with an inducible Xist allele (iXist-ChrX mESCs) and integrate allele-specific data of gene silencing and decreasing inactive X (Xi) chromatin accessibility over time courses of Xist induction with cellular differentiation. …”

Meaning and speech acts by Rumfitt, I

“…The chapter concludes with some initial remarks about the shape of a semantic theory cast on Strawsonian lines.…”

From cosmos to cell: constructing a paradoxical selfhood through planetary and biological bodies in the poetry of Diane Ackerman and Jane Hirshfield by Tan, Jasmine Hui Jun

“…The research project will analyze fourteen poems by Ackerman and Hirshfield, collectively published over the span of approximately four decades and across nine different collections, focusing on poetic journeys that oscillate between material and immaterial reality, traveling into and through the body and beyond. …”
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君绍的散文研究 ：本土的观察、记忆与反思 = A study of Jun Shao’s prose: local observation, memory and reflection by 陈姿潔 Tan, Zi Jie

“…He started writing in the 1950s and his writing career spanned more than half a century. Jun Shao often drew his inspirations from the nature, and with his keen observations and profound knowledge in botany, he had made a name for himself with his extraordinary depiction of nature through his writings. …”
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The development and validation of digital medical education environment (digimee) instrument in measuring online learning environment for undergraduate medical students by Haris, Noor-I-Kiran

“…The study was designed as a multi-phase mixed- methods research project conducted in online settings involving a diverse group of experts, teachers, and instructional designers and multiple medical colleges in Pakistan ( Phase 2 and 3), spanning 18 months. In Phase 1, experts in medical education and technology-enhanced learning identified and validated components of online learning environments through a scoping review and a modified e-Delphi study. …”
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Aphid Resistance Segregates Independently of Cardenolide and Glucosinolate Content in an Erysimum cheiranthoides (Wormseed Wallflower) F2 Population by Mirzaei, Mahdieh, Younkin, Gordon C., Powell, Adrian F., Alani, Martin L., Strickler, Susan R., Jander, Georg

“…However, this variation in defensive metabolites could not explain the differences in aphid growth on the two parental lines, suggesting that processes other than the abundance of glucosinolates and cardenolides have a predominant effect on aphid resistance in E. cheiranthoides.…”
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