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  1. 1601

    Chromatin structuring factor HMGA2 controls subtelomere stability and cancer chemosensitivity by Syed Moiz Ahmed

    Published 2020
    “…To dwell deeper into HMGA2’s proposed chaperone function, I utilized four different cancer cell line model systems and induced replication/topological stress by targeting DNA polymerase or topoisomerases. …”
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    Thesis-Doctor of Philosophy
  2. 1602

    Sociospatial reframing of walking through inclusive streets and urban heritage by Wang, Yongcheng

    Published 2020
    “…The analysis revealed broad themes such as a vision of a “car-lite” city and the broadening scope of urban heritage, and specific themes such as heritage trails for learning while walking and the blurred line between locals and tourists. Furthermore, insight into policy implications was derived from a mixed-methods study of the public consultation exercise on urban redevelopment in Macao. …”
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    Thesis-Doctor of Philosophy
  3. 1603
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    Functional analysis of germline RAD51C missense variants highlight the role of RAD51C in replication fork protection by Kolinjivadi, Arun Mouli, Chong, Siao Ting, Choudhary, Ramveer, Sankar, Haresh, Chew, Ee Ling, Yeo, Claresta, Chan, Sock Hoai, Ngeow, Joanne

    Published 2023
    “…Investigations using patient-derived lymphoblastoid cell line carrying heterozygous RAD51C L134S variant showed an impairment in RAD51 chromatin association and replication fork protection, suggestive of deleteriousness of this VUS variant. …”
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    Journal Article
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  12. 1612

    Culture of human pluripotent stem cells and neural networks in 3D using an optogenetic approach and a hydrogel model by Lee, S

    Published 2016
    “…Viability of the cells at 7 day-post-infection was 80% - 97% in all conditions tested. In line with published literature, transduction efficiency of neurons at day 14 was found to be 3% - 7% for plasmids containing the SYN1 promoter and 2% - 5% for plasmids containing the CaMKII promoter. …”
    Thesis
  13. 1613

    Effects of Edible bird's nest on quality of Arabian stallion semen and post-breeding induced endometritis in mares by Al-Khaldi, Khalid Obaid Salim

    Published 2022
    “…E-Z mixin® treated semen had significantly higher TM, PM, average path velocity (VAP), straight-line velocity (VSL) and curvilinear velocity (VCL) compared to EquiPlus® at either 24 and/or 48 h. …”
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    Thesis
  14. 1614

    A standardised fraction 1 (SF1) from clinacanthus nutans attenuates the stemness of cervical cancer stem-like cells via inhibition of notch1 signalling by Ismail, Faridah

    Published 2024
    “…Bioassay guided fractionation was employed for the isolation of SF1 from C. nutans leaf extract. The SiHa cell line was used for the enrichment of CCSCs by culturing the cells in CSC-conditioned medium (cervospheres). …”
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    Thesis
  15. 1615

    Use of smartphones to detect diabetic retinopathy : scoping review and meta-analysis of diagnostic test accuracy studies by Tan, Choon Han, Kyaw, Bhone Myint, Smith, Helen, Tan, Colin Siang Hui, Car, Lorainne Tudor

    Published 2021
    “…This review is reported in line with the Preferred Reporting Items for a Systematic Review and Meta-analysis of Diagnostic Test Accuracy Studies guidelines. …”
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    Journal Article
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  19. 1619

    Shaped Bessel beam singulation of glass substrates by Chia, Hao Guang

    Published 2022
    “…However, the heat generated can cause chipping and debris along the cut line. In addition, the area surrounding the cut often has heat damage, which alters the material's mechanical properties. …”
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    Final Year Project (FYP)
  20. 1620

    Development of reconstructed intestinal micronucleus cytome (RICyt) assay in 3D human gut model for genotoxicity assessment of orally ingested substances by Lim, Hui Kheng, Hughes, Christopher Owen, Lim, Michelle Jing Sin, Li, Jia'En Jasmine, Rakshit, Moumita, Yeo, Calvin, Chng, Kern Rei, Li, Angela, Chan, Joanne Sheot Harn, Ng, Kee Woei, Leavesley, David Ian, Smith, Benjamin Paul Chapman

    Published 2022
    “…Micronucleus assays typically utilise homogenous in vitro cell lines which poorly recapitulate the physiology, biochemistry and genomic events in the gut, the site of first contact for ingested materials. …”
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    Journal Article