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12421
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12422
Bioinspired, ingestible electroceutical capsules for hunger-regulating hormone modulation
Published 2024“…Electrical stimulation has also been used to attempt to modulate the gut-brain axis with greater spatial and temporal resolution. …”
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12423
Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism
Published 2024“…However, identifying the direct roles of B-lamins on dynamic genome organization has been challenging as their joint depletion severely impacts cell viability. …”
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12424
Re-evaluating GPT-4’s bar exam performance
Published 2024“…Perhaps the most widely touted of GPT-4’s at-launch, zero-shot capabilities has been its reported 90th-percentile performance on the Uniform Bar Exam. …”
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12425
Multi-Keel Passive Prosthetic Foot Design Optimization Using the Lower Leg Trajectory Error Framework
Published 2024“…Single-keel energy storage and return (ESR) prosthetic feet have recently been developed to provide improved walking benefits at an affordable cost in LMICs. …”
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12426
Development of a Self-Report Measure of Prediction in Daily Life: The Prediction-Related Experiences Questionnaire
Published 2024“…Disruptions to prediction abilities have been proposed to underlie characteristics associated with autism. …”
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12427
Oral Carbon Monoxide Enhances Autophagy Modulation in Prostate, Pancreatic, and Lung Cancers
Published 2024“…However, the clinical efficacy of autophagy inhibitors has been inconsistent. To delineate clinical and epidemiological features associated with autophagy inhibition and a positive oncological clinical response, a retrospective analysis of patients is conducted treated with hydroxychloroquine, a known autophagy inhibitor. …”
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12428
Ketamine can produce oscillatory dynamics by engaging mechanisms dependent on the kinetics of NMDA receptors
Published 2024“…Ketamine’s primary molecular targets and its oscillatory dynamics have been characterized. However, how the actions of ketamine at the subcellular level give rise to the oscillatory dynamics observed at the network level remains unknown. …”
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12429
Manufacturing mesenchymal stromal cells in a microcarrier-microbioreactor platform can enhance cell yield and quality attributes: case study for acute respiratory distress syndrome
Published 2024“…Mesenchymal stem and stromal cells (MSCs) hold potential to treat a broad range of clinical indications, but clinical translation has been limited to date due in part to challenges with batch-to-batch reproducibility of potential critical quality attributes (pCQAs) that can predict potency/efficacy. …”
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12430
Time-series metagenomics reveals changing protistan ecology of a temperate dimictic lake
Published 2024“…Metagenomic samples have been collected and shotgun sequenced from Lake Mendota for the last 20 years. …”
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12431
Predicted Losses of Sulfur and Selenium in European Soils Using Machine Learning: A 2 Call for Prudent Model Interrogation and Selection
Published 2024“…Reductions in sulfur (S) atmospheric deposition in recent decades have been attributed to S deficiencies in crops. Similarly, global soil selenium (Se) concentrations were predicted to drop, particularly in Europe, due to increases in leaching attributed to increases in aridity. …”
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12432
Insights into Li+ Storage Mechanisms, Kinetics, and Reversibility of Defect-Engineered and Functionalized Multi-Walled Carbon Nanotubes for Enhanced Energy Storage
Published 2024“…To overcome these challenges, multi-walled carbon nanotubes (MWCNTs) have been explored as an alternative, offering Li+ storage within the interplanar space between graphene sheets, along with excellent electrical conductivity, and eco-friendliness. …”
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12433
Development and Characterization of a Novel, Low-Cost Method for Measurement of Volatile Organic Compounds
Published 2024“…While there are several commercially-available LCS that can measure environmental volatile organic compounds (VOCs), an important class of hazardous pollutants, these sensors can only make non-specific “broadband” measurements and have, to date, been underutilized in research. This thesis describes the development, characterization, optimization, and use of a novel low-cost instrument for measuring environmental VOCs. …”
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Thesis -
12434
The Relationship between Linguistic Representations in Biological and Artificial Neural Networks
Published 2024“…The scientific tools for investigating human-unique capacities, such as language, have long been limited. For example, we do not have the option to learn about the neural circuits that support these capabilities by studying simpler systems than the human brain, such as animal models. …”
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12435
Structure and dynamics of magnetic domain walls in multi-sublattice magnetic oxides
Published 2024“…Recently, DMI and even faster DW motion have been observed in thin-film rare-earth iron garnets. …”
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12436
Design and Synthesis of Stimuli-Responsive Polymers with Programmable Cleavability
Published 2024“…The first chapter introduces bottlebrush polymers as nanocarriers for therapeutics, and provides a detailed literature analysis of the synthetic and architectural developments that have been reported for these constructs, as well as outlooks for the future. …”
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12437
Trouble on the Range: When Does a National Park Become a Bison Zoo?
Published 2024“…One of these valleys, Lamar, is a hotspot for bison viewing, but, unbeknownst to many casual tourists, the area has also long-been the center of an intense scientific debate. …”
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12438
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12439
Emergence, Formation and Dynamics of Hot QCD Matter
Published 2024“…Over the past two decades it has been realized that a significant fraction of quarkonium suppression in high energy heavy ion collisions comes from dynamic dissociation and recombination processes, instead of static screening of the interaction potential as originally proposed by Matsui and Satz. …”
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12440
Analysis of Poly(ethylene terephthalate) degradation kinetics of evolved IsPETase variants using a surface crowding model
Published 2024“…IsPETase also displays enzyme concentration-dependent inhibition effects, and surface crowding has been proposed as a causal phenomenon. Based on total internal reflectance fluorescence microscopy and adsorption experiments, IsPETase is likely experiencing crowded conditions on PET films. …”
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