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1821
Novel technologies for cell culture and tissue engineering
Published 2017“…The H1299 cells were seeded onto inspected corneal scaffold and BIS system, which were realized in the previous chapter, were used to validate its applicability for 3D cell culture. …”
Thesis -
1822
Investigating the content and function of stress-induced extracellular vesicles in colorectal cancer
Published 2021“…</p> <p>My final results chapter focussed on EV-associated microRNA cargo within HCT116 and SW480 cells, as well as within a cohort of patients with rectal cancer treated with neoadjuvant chemoradiotherapy (nCRT). …”
Thesis -
1823
Neural combinatorial optimization: from routing to integer programming
Published 2022“…To overcome the above issues, the neural combinatorial optimization (NCO) domain comes into being, which refers to the research and applications of deep learning for solving COPs. …”
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Thesis-Doctor of Philosophy -
1824
Biomarkers and cognition study, Singapore (BIOCIS): protocol, study design, and preliminary findings
Published 2024“…Background: The focus of medicine is shifting from treatment to preventive care. The expression of biomarkers of dementia and Alzheimer’s disease (AD) appear decades before the onset of observable symptoms, and evidence has emerged supporting pharmacological and non-pharmacological interventions to treat modifiable risk factors of dementia. …”
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Journal Article -
1825
A high-performance main-memory query engine on emerging many-core processors
Published 2018“…We recognize that a key component of ageless computing systems is the storage, processing, and management of data collected from the elderly people, based on which customized cares can be provided. For example, health care providers can provide more fine-grained and accurate services to the elderly if they are enabled to track important bio-metrics and analyze them in a timely manner for each elderly individual. …”
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Thesis-Doctor of Philosophy -
1826
Pregnant women admitted to hospital with covid-19 in 10 European countries: individual patient data meta-analysis of population based cohorts in International Obstetric Survey Syst...
Published 2024“…Moderate to severe covid-19 disease was defined as maternal death, admission to an intensive care unit, or need for respiratory support.</p> <p><strong>Results</strong> Among 1.7 million maternities, 9003 women were included in the study: 2350 (26.1%) were admitted to hospital because of covid-19 disease or had symptoms of disease. …”
Journal article -
1827
Optimization and scheduling for a large-scale urban transportation system involving human factors
Published 2020“…The thesis includes three technical chapters: The first technical chapter develops a model to provide traffic light scheduling for pedestrian-vehicle mixed-flow networks, where a macroscopic pedestrian "hopping" model at an intersection is formulated, which is capable of reflecting the changing capacity during one time interval resulted from the crosswalk length and pedestrian relatively lower speed. …”
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Thesis-Doctor of Philosophy -
1828
Electrochemical DNA biosensor based on nanoporous alumina membrane
Published 2014“…Thus, the effective detection technique will be useful in cutting down the risk of transmission of disease. In the following chapter, we demonstrated a novel and integrated membrane sensing platform relying on free-standing anodic aluminum oxide (AAO) for the detection of oligonucleotide sequence using electrochemical impedance spectroscopy. …”
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Thesis -
1829
“新游牧精神”为文化冲突的和解方案 :从《陆犯焉识》探讨严歌苓的身份认同 = “New normadic spirit” as a solution to cultural identity conflict : an analysis of Yan Ge Ling’s cultural identity through her novel, Lu Fan...
Published 2015“…Bringing together the experiences of the novel’s characters, their dilemmas between staying or leaving, and the closing chapter; as well as Yan Ge Ling’s own life, it becomes apparent that the “New Nomadic Spirit” is uniquely transcendental, going beyond the original cultural referents of identity. …”
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Final Year Project (FYP) -
1830
Predictors and outcomes of healthcare-associated infections caused by carbapenem-nonsusceptible enterobacterales: a parallel matched case-control study
Published 2023“…Methods: We conducted a multi-centre parallel matched case-control study in two 1700-bedded Singapore acute-care hospitals from 2014–2016. Patients with CnSE-HAIs and CSE-HAIs were compared to a common control group without HAIs (1:1:3 ratio), matched by time-at-risk and patient ward. …”
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Journal Article -
1831
Interventions for managing skeletal muscle spasticity following traumatic brain injury
Published 2018“…Secondary outcome measures were classified according to the World Health Organization International Classification of Functioning, Disability and Health including body functions (sensory, pain, neuromusculoskeletal and movement‐related functions) and activities and participation (general tasks and demands; mobility; self‐care; domestic life; major life areas; community, social and civic life). …”
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Journal Article -
1832
Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 countries, 1990–2013:...
Published 2015“…Many prevention and primary care policy options are available now to act on key risks. …”
Journal article -
1833
Assessing long-term effectiveness and cost-effectiveness of statin therapy in the UK: a modelling study using individual participant datasets
Published 2024“…UK primary and hospital care data informed healthcare costs (2020/2021 UK£); £1.22 standard or £1.68 higher intensity generic statin therapy per 28 tablets; and Health Survey for England data informed health-related quality of life. …”
Journal article -
1834
Physiological stress responses and meat quality of rabbits subjected to different road transportation and slaughter methods
Published 2014“…All in all, the present study has shown than that transport and slaughter caused substantial physiological stress responses, and even though these may not necessarily translate into compromising of animal welfare, care must be taken to avoid reaching the threshold to negatively affect meat quality. …”
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Thesis -
1835
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1836
Study on process parameter optimization for electron beam melting additive manufacturing
Published 2021“…Moreover, the significance and potential industrial applications of the ML-centered tetrahedral framework are depicted in the general discussion chapter of the thesis. Last but not least, the established ML-empowered methodology for process parameter optimization based on SEBM processing in this study can also be applied to other metal AM processes, such as laser-based powder bed fusion, directed energy deposition and binder jetting.…”
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Thesis-Doctor of Philosophy -
1837
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1838
Therapeutic effects of Cosmos caudatus kunth leaf extract in the prevention and treament of obesity in sprague dawley rats
Published 2015“…Finally, partial least square analysis (PLS-DA) showed that the obese group moved away from the position of lean group and after 9 weeks of treatment both treated groups were regulated back closer towards their healthy baseline levels,confirming the therapeutic effects of the extracts obtained from biochemical assays measured in the previous chapter. This study showed the antiobesity effects of C. caudatus through inhibition of lipase activity as demonstrated by the increase in fecal fat content and also the positive effects on other obesity biomarkers measured. …”
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Thesis -
1839
Understanding the role of Enterococcus faecalis in polymicrobial wounds
Published 2023“…Evaluating wound healing parameters next in E. faecalis-positive polymicrobial wounds will unveil if the species can be of utility in chronic wound healing, circumventing the need for wound debridement and antibiotics, and thereby reducing the cost of chronic wound care through personalized wound therapy.…”
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Thesis-Doctor of Philosophy -
1840
Integrative genomic analyses in adipocytes implicate DNA methylation in human obesity and diabetes
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Journal Article