Identification of FGF receptor-binding peptides for cancer gene therapy by Maruta, F, Parker, AL, Fisher, KD, Hallissey, MT, Ismail, T, Rowlands, DC, Chandler, LA, Kerr, DJ, Seymour, LW

“…MQLPLAT phage showed only limited binding to Cos7 cells deficient in receptors for FGF. MQLPLAT phage bound to SKOV3 cells with a Kd of 2.51×10−10 M. …”

Modulation of affinity of a marine pseudomonad for toluene and benzene by hydrocarbon exposure by Law, A.T., Button, D.K.

“…Trace (microgram liter-1) quantities of either toluene or benzene injected into an amino-acid limited continuous culture of Pseudomonas sp. strain T2 were utilized immediately with affinities of 2.6 and 6.8 liters g of cells-1 h-1, respectively, and yielded large amounts of organic products, carbon dioxide, and cells. …”
Get full text

Benzofuran-based estrogen receptor α modulators as anti-cancer therapeutics : in silico and experimental studies by Leow, Min Li, Chin, Christina Hui Li, Yu, Peggy Shuang, Pasunooti, Kalyan Kumar, Tay, Raymond Xu Zhan, Zhang, Dawei, Yoon, Ho Sup, Liu, Xue-Wei

“…In addition, the apoptotic abilities of the compounds have been measured in both MCF-7 ER(+) and MDA-MB-231 ER(-) breast cancer cells. The results demonstrated that our compounds inhibit MCF-7 breast cancer cells via ER(+). …”
Get full text
Get full text

Dynamic altruistic cooperation within breast tumors by Muhammad Sufyan Bin Masroni, Lee, Kee Wah, Lee, Victor Kwan Min, Ng, Siok Bian, Law, Chao Teng, Poon, Kok Siong, Lee, Bernett Teck Kwong, Liu, Zhehao, Tan, Yuen Peng, Chng, Wee Ling, Tucker, Steven, Ngo, Lynette Su-Mien, Yip, George Wai Cheong, Nga, Min En, Hue, Susan Swee Shan, Putti, Thomas Choudary, Bay, Boon Huat, Lin, Qingsong, Zhou, Lihan, Hartman, Mikael, Loh, Tze Ping, Lakshmanan, Manikandan, Lee, Sook Yee, Tergaonkar, Vinay, Chua, Huiwen, Lee, Adeline Voon Hui, Yeo, Eric Yew Meng, Li, Mo-Huang, Chang, Chan Fong, Kee, Zizheng, Tan, Karen Mei-Ling, Tan, Soo Yong, Koay, Evelyn Siew-Chuan, Archetti, Marco, Leong, Sai Mun

“…This multidisciplinary study explores altruism and its mechanism in breast cancer cells and its contribution to chemoresistance.…”
Get full text

Structure of mushy layers grown from perfectly and imperfectly conducting boundaries. Part 2. Onset of convection by Hitchen, JR, Wells, AJ

“…A companion paper (Hitchen & Wells, J. Fluid Mech., 2025, in press) showed how thermal and salinity conditions impact mush structure. …”

Development of solar power systems for solar UAV : evaluation of nomura MPPTs at sub-zero temperatures & solar modules encapsulation by Teo, Boon Rong

“…In addition, the energy generated by the solar cells at the time of Flight Test at India, Kanpur was calculated to check if the number of solar cells to be placed on the wing is sufficient. …”
Get full text

Toxicity, permeability and drug-metabolizing enzyme activities of curcumin analogues by Yakubu, Ndatsu

“…The activities of drug-metabolizing enzymes (CPR,UGT, GST and SULT) in cells and adult male zebrafish subjected to all test compounds, separately, as compared to that of normal cells and zebrafish demonstrated that MS65 is better than BDMC33, followed by EF-24 and then curcumin. …”
Get full text

Improving detection of chromosomal abnormalities in multiple myeloma using fluorescence in situ hybridization by Naw, Wah Wah

“…Multiple myeloma (MM) cells are hypoproliferative and thus 70% of MM cases are not detected in conventional cytogenetic (CC) that analyses chromosomal abnormality in metaphase cells. …”
Get full text

Membrane filtration of microalgae by We, Sok Ling.

“…The micrographs revealed the characteristics of algal cells before and after filtration, and the surface architecture of deposits on the fouled membrane. …”
Get full text

Biodegradable polymer-coated multifunctional graphene quantum dots for light-triggered synergetic therapy of pancreatic cancer by Yang, Chengbin, Chan, Kok Ken, Xu, Gaixia, Yin, Ming-jie, Lin, Guimiao, Wang, Xiaomei, Lin, Wei-Jen, Muhammad Danang Birowosuto, Zeng, Shuwen, Ogi, Takashi, Okuyama, Kikuo, Permatasari, Fitri Aulia, Iskandar, Ferry, Chen, Chih-Kuang, Yong, Ken-Tye

“…The resulting nanocomplexes have demonstrated high stability in physiologically mimicking media, excellent K-ras downregulation activity, and effective bioactivity inhibition for MiaPaCa-2 cells. More importantly, laser light was used to generate heat for the nanocomplexes via the photothermal effect to damage the cells, which was further employed to trigger the release of payloads from the nanocomplexes. …”
Get full text

Clinical- and omics-based models of subclinical atherosclerosis in healthy Chinese adults: a cross-sectional exploratory study by Valsesia, Armand, Egli, Leonie, Bosco, Nabil, Magkos, Faidon, Kong, Siew Ching, Sun, Lijuan, Goh, Hui Jen, Huang, Weiting, Arigoni, Fabrizio, Leow, Melvin Khee-Shing, Yeo, Khung Keong, Actis-Goretta, Lucas

“…Background: Classical risk factors, such as fasting cholesterol, blood pressure (BP), and diabetes status are used today to predict the risk of developing cardiovascular disease (CVD). …”
Get full text

Sustained exposure to Helicobacter pylori induces immune tolerance by desensitizing TLR6 by Zhang, Xiulin, He, Yang, Zhang, Xiaolu, Fu, Bo, Song, Zidai, Wang, Liang, Fu, Rui, Lu, Xuancheng, Xing, Jin, Lv, Jianyi, Guo, Meng, Huo, Xueyun, Liu, Xin, Lu, Jing, Du, Xiaoyan

“…The gastric epithelium acts as the first line of defense against H. pylori, with Toll-like receptors (TLRs) in gastric epithelial cells being sensitive to H. pylori components and subsequently activating the innate immune system. …”
Get full text

Genetic, genomic and systems biology analysis of adaptive evolution of budding yeast to the deletion of essential genes by Liu, Gaowen

“…Dissection of the molecular mechanism at the basis of the adaptation showed that cells bypassed the crippled function not by fixing the broken machinery but by tinkering with pre-existing components and using them for novel tasks. …”
Get full text

Graphene-based materials for energy conversion by Sahoo, Nanda Gopal, Pan, Yongzheng, Li, Lin, Chan, Siew Hwa

“…Recently, the fabrication of fuel cells and solar cells using graphene for various functional parts has been studied extensively. …”
Get full text
Get full text

GPU accelerated image quality assessment-based software for transient detection by Li, X, Adamek, K, Armour, W

“…Fast imaging localises celestial transients using source finders in the image domain. …”

Mannitol enhances antibiotic sensitivity of persister bacteria in Pseudomonas aeruginosa biofilms by Rice, Scott A., Barraud, Nicolas, Buson, Alberto, Jarolimek, Wolfgang

“…Here, we used the commonly prescribed aminoglycoside tobramycin to select for P. aeruginosa persister cells during biofilm growth. Incubation with mannitol (10–40 mM) increased tobramycin sensitivity of persister cells up to 1,000-fold. …”
Get full text
Get full text

Electrospinning a small diameter tubular scaffold for tissue engineering blood vessels by Tay, Kulapattra Chongwen.

“…This alignment mimics the respective directions of the endothelial cells and smooth muscle cells in the human blood vessel. …”
Get full text

Design, synthesis, characterization and property study of topological structures of DNA by Li, Dawei

“…It has been recognized in the past that alteration of writhe of DNA in prokaryotic and eukaryotic cells is maneuvered solely by histone proteins and topological enzymes such as gyrase, reverse gyrase, topo I and topo II. …”
Get full text

Calcium regulation of glucagon-like peptide-1 secretion. by Chua, Sharon Chia Ling.

“…Glucagon-like peptide (GLP-1), a hormone secreted from enteroendocrine L-cells in response to nutrient ingestion. Because of its strong potentiating effect on insulin release, GLP-1 now becomes a basis for new class diabetes treatment strategies. …”
Get full text

Segmentation of histopathological images by Chia, Jason

“…This project aims to segment histopathological images of lung tissues into its constituents such as cells, nuclei and blood vessels so that the status of the patients can be determined.…”
Get full text