Co-designing the implementation of a rural health systems-strengthening rheumatic heart disease program with remote First Nations Australian communities using Theory of Change by Jones, B, Mitchell, A, Haynes, E, Howard, NJ, Wade, V, Pears, C, Rossingh, B, Gatti, J, Ramadani, S, Corpus, E, Yan, J, Marangou, J, Kaethner, A, Bailey, M, Francis, JR, English, M, Nagraj, S

“…Implementing new models of care within remote communities, however, requires local knowledge, cultural and operational adaptation, whilst ensuring consistency and quality assurance across multiple sites. …”

Early, very high-titre convalescent plasma therapy in clinically vulnerable individuals with mild COVID-19 (COVIC-19): protocol for a randomised, open-label trial by Desmarets, M, Hoffmann, S, Vauchy, C, Rijnders, BJA, Toussirot, E, Durrbach, A, Körper, S, Schrezenmeier, E, van der Schoot, CE, Harvala, H, Brunotte, G, Appl, T, Seifried, E, Tiberghien, P, Bradshaw, D, Roberts, DJ, Estcourt, LJ, Schrezenmeier, H

“…</p> <p><strong>Methods and analysis:</strong>&nbsp;COVIC-19 is a multicentre, randomised, open-label, adaptive superiority phase III trial comparing CCP with very high neutralising antibody titre administered within 7&thinsp;days of symptom onset plus standard of care versus standard of care alone. We will enrol patients in two cohorts of vulnerable patients [(1) elderly 70+ years, or younger with comorbidities; (2) immunocompromised patients]. …”

Multicenter double-blind study evaluating AI-driven detection of proximal deep vein thrombosis by Curry, N, Allen, E, Silsby, L, Goodacre, S, Deane, C, Deary, A, Foster, A, Griffiths, J, Sharma, R, Thomas, H, Mischewitz, S, Al-Noor, F

“…In at least 80% of cases, DVT is excluded. As health care provision becomes increasingly stretched, resource utilization needs to be optimized. …”

Remote vital sign monitoring in admission avoidance hospital at home: a systematic review by Patel, R, Thornton-Swan, TD, Armitage, LC, Vollam, S, Tarassenko, L, Lasserson, DS, Farmer, AJ

“…Vital sign monitoring can support HAH acute multidisciplinary care by contributing to safety, determining requirement of further assessment, and guiding clinical decisions. …”

Effectiveness of fludrocortisone plus hydrocortisone versus hydrocortisone alone in septic shock: a systematic review and network meta-analysis of randomized controlled trials by Teja, B, Berube, M, Pereira, TV, Law, AC, Schanock, C, Pang, B, Wunsch, H, Walkey, AJ, Bosch, NA

“…Treatment effects are presented as relative risks (RRs) with 95% credible intervals (CrIs). Placebo or usual care was the reference treatment. <p><strong> Measurements and Main Results: </strong></p> Among 7,553 references, we included 17 trials (7,688 patients). …”

Exploring critical components of physician-patient communication: a qualitative study of lay and professional perspectives by Mohd Salim, Nurul, Roslan, Nurhanis, Hod, Rafidah, Zakaria, Syahiera, Adam, Siti

“…Patients and relatives were more interested in the physician’s advice regarding their diet, care plans, physical activities, and daily routine. …”
Get full text

Total Synthesis of Verticillin A and Application of Diazene-Directed Fragment Assembly to the Synthesis of Heterodimeric Epidithiodiketopiperazine Derivatives by Knauss, Walker

“…This is the first application of diazene-directed coupling to the synthesis of dimeric diketopiperazine alkaloids Our group’s initial route to heterodimeric ETP derivatives relied upon reductive cobalt dimerization, which produces a nearly statistical mixture of homo- and heterodimeric products. …”
Get full text

Coherent Terahertz Control and Ultrafast Spectroscopy of Layered Antiferromagnets by Ilyas, Batyr

“…Critical fluctuations near the phase transition are found to enhance both the magnitude and the lifetime of this new state. …”
Get full text

Towards a Single Bio-molecule Detector Based on CMOS Nanofluidic Platform by Zikrallah, Ahmed S.

“…A silicon Single Photon Avalanche Detectors (SPADs) was also implemented and placed near the nanochannels to utilize fluorescence labeling imaging techniques. …”
Get full text
Get full text

Direction finding for UWB RFID system in dense cluttered environments by Luo, Yanjia

“…A channel model of plane waves from far-field reflectors or scatterers superimposed with near-field interferences is proposed, and the Cram´er-Rao bounds for ranging and direction finding are derived to analyze the channel effects. …”
Get full text

Fluid velocity slip and temperature jump at a solid surface by Teo, Melvin Ji Bin

“…The net velocity and temperature of the near-wall molecules, equivalent to the slip velocity and temperature jump, can be evaluated by considering the relative rates of adsorption. …”
Get full text

The fabrication and characterization of double waveguide ridge terahertz quantum cascade laser by Li, Jinghao

“…The double-metal waveguide is a most widely-used scheme, which can realize a nearly 100% modal confinement. The ability to make a double-metal based waveguide ridge laser is very useful. …”
Get full text

Fabrication and characterization of Si doped ZnO and Cu2P2O7 thin films by Wang, J

“…<p>Transparent conductive oxides (TCOs) are a group of materials that have good electrical conductivity, high visible and low near infrared (NIR, 790–2500 nm) transparencies. …”

Shape-morphing structures based on perforated kirigami by Zhang, Yunlan, Yang, Jingyi, Liu, Mingchao, Vella, Dominic

“…We also examine the loading-bearing capacity of morphed structures via indentation tests in both FEM simulations and experiments. …”
Get full text

Novel bisisoquinolines : synthesis, resolution and application in asymmetric Henry reaction by Yao, Qiong Ji

“…(R)-N-alkyl-C1-1’,2’,3’,4’-terahydro-1,1’-bisisoquinoline differing in the steric bulkiness were successfully afforded to be examined in the asymmetric Henry reaction. The ligand bearing the smallest substituent was proved to be the most effective one in the CuI-catalyzed addition of nitromethane, nitroethane and nitropropane to aldehydes. …”
Get full text

Diffuse Correlation Spectroscopy (DCS) and Diffuse Optical Spectroscopy (DOS) for photodynamic therapy monitoring. by Siti Raudhah Matyasir.

“…The aim is to evaluate the relative tissue oxygen saturation (rStO2) and relative blood flow (rBF) of the tumour-bearing mice obtained from Diffuse Optical Spectroscopy (DOS) and Diffuse Correlation Spectroscopy (DCS) respectively in order to see if they have prognostic value in predicting tumour response. …”
Get full text

Role of posttranslational modifications of histone proteins in epigenetics by Raj, R

“…Using a "Tag-and-modify" approach, modified histone proteins bearing both modifications was synthesized, and was later used for nucleosome reconstitution. …”

Functional genetics of cancer and congenital disorders by Zak, J

“…An integrative analysis of cancer genomic data revealed that <em>PPP1R13B</em>, encoding ASPP1, bears many hallmarks of a tumour suppressor gene, despite being mutated at a low absolute frequency. …”

Targeting c-Met for endoscopic detection of dysplastic lesions within Barrett’s esophagus using EMI-137 fluorescence imaging by Huang, Y-J, Rieder, J, Tan, KV, Tenditnaya, A, Vojnovic, B, Gorpas, D, Quante, M, Vallis, KA

“…EMI-137 was tested in a dual xenograft mouse model bearing OE33 (c-MET high expression) and FLO-1 (c-MET low expression) tumors. …”

Social Media Marketing Adoption among SMEs in Malaysia and Nigeria (S/O 14089) by Ramanchandram, Rajoo, Abdullah, Shahmir Sivaraj, Kolandaisamy, Indraah, Soo, Hooi Sin, Mohd Jani, Mohamad Yusop

“…It is not surprising that the relevant factors above have a strong bearing in both Malaysia and Nigeria even though they are continents apart. …”
Get full text