Multiplexed CRISPR/CAS9‐mediated engineering of pre‐clinical mouse models bearing native human B cell receptors by Wang, Xuesong, Ray, Rashmi, Kratochvil, Sven, Melzi, Eleonora, Lin, Ying‐Cing, Giguere, Sophie, Xu, Liling, Warner, John, Cheon, Diane, Liguori, Alessia, Groschel, Bettina, Phelps, Nicole

“…We demonstrate that B cells from these mice are fully functional: upon transfer to congenic, wild type mice at controlled frequencies, such B cells can be primed by eOD‐GT8 60mer, a germline‐targeting immunogen currently in clinical trials, recruited to germinal centers, secrete class‐switched antibodies, undergo somatic hypermutation, and differentiate into memory B cells. …”
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Noninnocent behavior of nitrosoarene-pyridine hybrid ligands : ruthenium complexes bearing a 2-(2-Nitrosoaryl)pyridine monoanion radical by Chan, Siu-Chung, England, Jason, Lee, Wing-Chun, Wieghardt, Karl, Wong, Chun-Yuen

“…Redox-active ligands: Structural, spectroscopic, and theoretical studies of ruthenium(II) complexes bearing 2-(2-nitrosoaryl)pyridine ligands and their reduced analogues reveals the redox noninnocence of 2-(2-nitrosoaryl)pyridine (see scheme).…”
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Design and implementation of a smart Internet of Things chest pain center based on deep learning by Li, Feng, Bi, Zhongao, Xu, Hongzeng, Shi, Yunqi, Duan, Na, Li, Zhaoyu

“…The resulting data are saved in the chest pain patient database and uploaded to the national chest pain center. The system has been used in Liaoning Provincial People's Hospital, and its subsequent assistance to doctors and nurses in collaborative treatment, data feedback and analysis is of great significance.…”
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Patient-Centered Clinical Trial Design for Heart Failure Devices via Bayesian Decision Analysis by Chaudhuri, Shomesh E., Adamson, Phillip, Bruhn-Ding, Dean, Ben Chaouch, Zied, Gebben, David, Rincon-Gonzalez, Liliana, Liden, Barry, Reed, Shelby D., Saha, Anindita, Schaber, Daniel, Stein, Kenneth, Tarver, Michelle E., Lo, Andrew W.

“…This result reflects the willingness of heart failure patients to bear additional risks of the investigational device in exchange for its probable benefits. …”
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The Inspiration Design Toolkit: A Human-Centered Design Tool for a System Engineering Course by Lee, Sheng-Hung, Yang, Maria C, Carramolino, Beatriz, Rudnik, John

“…In this paper, we describe the outcomes of introducing a human-centered design tool, the Inspiration Design Toolkit (IDT), to encourage students to think non-linearly. …”
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Hierarchical eye-tracking data analytics for human fatigue detection at a traffic control center by Li, Fan, Chen, Chun-Hsien, Xu, Gangyan, Khoo, Li-Pheng

“…Eye-tracking-based human fatigue detection at traffic control centers suffers from an unavoidable problem of low-quality eye-tracking data caused by noisy and missing gaze points. …”
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Off-centering of Ge atoms in GeBi2Te4 and impact on thermoelectric performance by Dong, Jinfeng, Hu, Lei, Liu, Jue, Liu, Yukun, Jiang, Yilin, Yu, Zhiling, Tan, Xian Yi, Suwardi, Ady, Zheng, Qiang, Li, Qian, Li, Jing-Feng, Dravid, Vinayak P., Yan, Qingyu, Kanatzidis, Mercouri G.

“…Neutron pair distribution function analysis revealed the presence of discordant Ge atoms with an off-centering distance of 0.12 Å at 300 K. The thermal conductivity of GeBi2Te4 is very low due to the strong phonon scattering. …”
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On P2P mechanisms for VM image distribution in cloud data centers : modeling, analysis and improvement by Wu, Di, Zeng, Yupeng, He, Jian, Liang, Yi, Wen, Yonggang

“…To provide elastic cloud services with QoS guarantee, it is essential for cloud data centers to provision virtual machines rapidly according to user requests. …”
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Throwing Out Conventions: Reimagining Craft-Centered CNC Tool Design through the Digital Pottery Wheel by Moyer, Ilan E, Bourgault, Samuelle, Frost, Devon, Jacobs, Jennifer

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Centering Indigenous Voices and Resisting Colonialism In Space Exploration: An Overview Of The Ongoing Webinar Series By Space Enabled by Tavares, Frank, Harvey, Alvin Donel, Lombardo, Seamus, Reynolds-Cuéllar, Pedro, Newman, Dava, Wood, Danielle

“…By understanding the ways in which past and present systems of coloniality intersect with the space sector and centering the experiences of Indigenous peoples in space exploration, a new way of conceptualizing space exploration can potentially emerge. …”
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A study of the electrification of the suburban zone of the New York, New Haven and Hartford Railroad centering in Boston by Bancker, Elbert H., Bangratz, Ernest George., Becker, James H. 1894-1970., Farist, Charles J., Moore, Irwin L.

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System-level experimental investigations of the direct immersion cooling data center units with thermodynamic and thermoeconomic assessments by Kanbur, Baris Burak, Wu, Chenlong, Fan, Simiao, Duan, Fei

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Toward human-centered automated driving: a novel spatiotemporal vision transformer-enabled head tracker by Hu, Zhongxu, Zhang, Yiran, Xing, Yang, Zhao, Yifan, Cao, Dongpu, Lv, Chen

“…Accurate dynamic driver head pose tracking is of great importance for driver–automotive collaboration, intelligent copilot, head-up display (HUD), and other human-centered automated driving applications. To further advance this technology, this article proposes a low-cost and markerless headtracking system using a deep learning-based dynamic head pose estimation model. …”
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A data-assisted first-principle approach to modeling server outlet temperature in air free-cooled data centers by Liu, Yingbo, Le, Duc Van, Tan, Rui

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A review of feature extraction methods in vibration-based condition monitoring and its application for degradation trend estimation of low-speed slew bearing by Caesarendra, Wahyu, Tjahjowidodo, Tegoeh

“…This paper presents an empirical study of feature extraction methods for the application of low-speed slew bearing condition monitoring. The aim of the study is to find the proper features that represent the degradation condition of slew bearing rotating at very low speed (≈ 1 r/min) with naturally defect. …”
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Search for continuous gravitational wave emission from the Milky Way center in O3 LIGO-Virgo data by Sudhir, Vivishek

“…We present a directed search for continuous gravitational wave (CW) signals emitted by spinning neutron stars located in the inner parsecs of the Galactic Center (GC). Compelling evidence for the presence of a numerous population of neutron stars has been reported in the literature, turning this region into a very interesting place to look for CWs. …”
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Looking at the Map, Together: Modeling Treatment Center Location Selection and its Effects on Access to Gene Therapy in Brazil by Wertheimer, Sarah R.

“…Patients in the northwest of Brazil would need stakeholders to consider candidate locations beyond government reference centers or those with gene therapy experience, in order to have a treatment center nearby. …”
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Effectiveness of clinician client-centered counseling on knowledge, attitudes and sexual bahaviors of antiretroviral therapy patients in Yola, Nigeria by Martins, Olutayo Folashade

“…Conclusion: Clinician client centered counseling is an effective behavioral intervention in improving knowledge, attitudes and sexual behaviors of ART patients. …”
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Desymmetrization of cyclic 1,3-Diketones under N-Heterocyclic carbene organocatalysis: access to organofluorines with multiple stereogenic centers by Wang, Guanjie, Zhang, Min, Guan, Yezhi, Zhang, Ye, Hong, Xianfang, Wei, Chenlong, Zheng, Pengcheng, Wei, Donghui, Fu, Zhenqian, Chi, Robin Yonggui, Huang, Wei

“…Accordingly, a versatile strategy for asymmetric generation of organofluorines with fluorine or fluorinated methyl groups has been developed. Multiple stereogenic centers were selectively constructed with satisfactory outcomes. …”
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Groups of profinite type and profinite rigidity by Bar-On, T, Nikolov, N