Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes by de Jesus, Daniel S., Mak, Tracy C. S., Wang, Yi-Fang, von Ohlen, Yorrick, Bai, Ying, Kane, Eva, Chabosseau, Pauline, Chahrour, Catherine M., Distaso, Walter, Salem, Victoria, Tomas, Alejandra, Stoffel, Markus, Rutter, Guy A., Latreille, Mathieu

“…Objective:b-cell dedifferentiation has been revealed as a pathological mechanism underlying pancreatic dysfunction in diabetes. …”
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Rotor angle stability-constrained dispatch and control of large-scale wind penetrated power system by Yuan, Heling

“…In current research, robust optimization has been demonstrated as an effective approach to deal with uncertainties and ensure the robustness. …”
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Mitofusins Mfn1 and Mfn2 are required to preserve glucose- but not incretin-stimulated β-cell connectivity and insulin secretion by Georgiadou, Eleni, Muralidharan, Charanya, Martinez, Michelle, Chabosseau, Pauline, Akalestou, Elina, Tomas, Alejandra, Yong, Fiona Su Wern, Stylianides, Theodoros, Wretlind, Asger, Legido-Quigley, Cristina, Jones, Ben, Lopez-Noriega, Livia, Xu, Yanwen, Gu, Guoqiang, Alsabeeh, Nour, Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Ali, Yusuf, Soleimanpour, Scott A., Linnemann, Amelia K., Rodriguez, Tristan A., Rutter, Guy A.

“…Whether mitofusin gene expression, and hence, mitochondrial network integrity, is important for glucose or incretin signaling has not previously been explored. Here, we generated mice with β-cell-selective, adult-restricted deletion knock-out (dKO) of the mitofusin genes Mfn1 and Mfn2 (βMfn1/2 dKO). βMfn1/2-dKO mice displayed elevated fed and fasted glycemia and a more than fivefold decrease in plasma insulin. …”
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Dynamics in blue emitting metal halide perovskites for light emitting diodes by Karlsson, Max

“…Successful implementation in LEDs has been attributed to efficient carrier funneling from large bandgap (donor) regions to low bandgap regions (acceptors) resulting in improved luminescence yields due to trap state filling from the locally increased carrier density. …”
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Mechanically durable and damage resilient dielectric elastomer actuators by Tan, Matthew Wei Ming

“…While various soft actuators have been designed, dielectric elastomer actuators (DEAs) have become prominent due to their rapid response times, large actuation strains, and energy densities. …”
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Short-wave infrared cavity resonances in a single GeSn nanowire by Kim, Youngmin, Assali, Simone, Joo, Hyo-Jun, Koelling, Sebastian, Chen, Melvina, Luo, Lu, Shi, Xuncheng, Burt, Daniel, Ikonic, Zoran, Nam, Donguk, Moutanabbir, Oussama

“…In contrast to impressive progress on light confinement and stimulated emission in III-V and II-VI semiconductor nanowires, there has been no experimental demonstration showing the potential to achieve strong cavity effects in a bottom-up grown single group-IV nanowire, which is a prerequisite for realizing silicon-compatible infrared nanolasers. …”
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Contact-free motion-robust vital signs monitoring by Zheng, Tianyue

“…Consequently, researchers have been pursuing contact-free alternatives to address these limitations. …”
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Innovation and firm survival: the role of timing, funding, and networks by Gao, Ming

“…While many studies have discussed how innovation influences firms’ survival, little has been done to explore how this relationship is shaped by other factors. …”
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Clinical course, immunogenicity, and efficacy of BNT162b2 mRNA vaccination against SARS-CoV-2 infection in liver transplant recipients by Tan, Eunice X., Lim, Wen Hui, Thong, Elizabeth, Chavatte, Jean-Marc, Zhang, Jinyan, Lim, Jonathan, Jin, Jocelyn Y., Lim, Daniel R. X., Kang, Jaclyn Y. T., Tang, Ansel Shao Pin, Chan, Kai En, Tan, Caitlyn, Tan, Shi Ni, Nah, Benjamin, Huang, Daniel Q., Wang, Lin-Fa, Tambyah, Paul A., Somani, Jyoti, Young, Barnaby Edward, Muthiah, Mark D.

“…Immunocompromised individuals have been excluded from landmark studies of messenger RNA vaccinations for severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2). …”
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Conflict-free urban air mobility planning with an airspace-resource-centric approach by Dai, Wei

“…The conventional air transport system has been operating for over a hundred years with great performances in both efficiency and safety, which raises high requirements for the future operations of UAM. …”
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Singlish与文化和国族认同： 以目的论分析网络视频 "Singapore Bootcamp" 和 "The Ah Bengs" 的 Singlish 翻译策略 = Singlish and national identity: a study on the Singlish translation of "Singapore Bootcamp" an... by 曹清雯 Cao, Qingwen

“…Translation of Singlish is a subject that has not been thoroughly researched. This paper intends to study the importance of translating Singlish and explore the possibility of it reflecting Singapore's culture and identity. …”
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Relative deficiency in interferon-γ-secreting CD4+ T cells is strongly associated with poorer COVID-19 vaccination responses in older adults by Ho, Vanda W. T., Boon, Low Heng, Cui, Jianzhou, Juequn, Zhou, Shunmuganathan, Bhuvaneshwari, Gupta, Rashi, Tan, Nikki Y. J., Qian, Xinlei, Purushotorman, Kiren, Fong, Siew-Wai, Renia, Laurent, Ng, Lisa F. P., Angeli, Veronique, Chen, Jinmiao, Kennedy, Brian K., Ong, Catherine W. M., Macary, Paul A.

“…Although the two-dose mRNA vaccination regime provides protection against SARS-CoV-2, older adults have been shown to exhibit poorer vaccination responses. …”
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Continuous health-based optimal operation and control for mission-critical power systems by Kumar, Logesh

“…In recent years’ lot of research has been conducted to detect the faults in the system, but very few and little work is reported on the mitigation and post fault scenario. …”
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Digital twin and AI enabled predictive maintenance in building industry by Hu, Wei

“…The effectiveness of PdM has also been hindered by the dependence on labelled datasets, which are expensive and time-consuming to generate. …”
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Yeast9: a consensus genome-scale metabolic model for S. cerevisiae curated by the community by Zhang, Chengyu, Sánchez, Benjamín J., Li, Feiran, Cheng, Eiden Wei Quan, Scott, William T., Liebal, Ulf W., Blank, Lars M., Mengers, Hendrik G., Anton, Mihail, Rangel, Albert Tafur, Mendoza, Sebastián N., Zhang, Lixin, Nielsen, Jens, Lu, Hongzhong, Kerkhoven, Eduard J.

“…Since Yeast8, the yeast-GEM of Saccharomyces cerevisiae, published in 2019, has been continuously updated by the community. This has increased the quality and scope of the model, culminating now in Yeast9. …”
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Leveraging linguistic knowledge to enhance low-resource NLP applications by Zhu, Zixiao

“…As a result, several training paradigms have been developed to enhance the downstream performance of PLMs, as outlined below. …”
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Solution based synthesis of Cu2ZnSnS4 nanoparticles and thin films for solar cell application by Li, Zhenggang

“…An encouraging power conversion efficiency of 8.4% has been achieved using vacuum deposition method. However, the vacuum deposition techniques are often associated with high energy input and thus impose a significant cost on the devices. …”
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Modeling and optimization of photovoltaic systems under partially shaded and rapidly changing conditions by Jiang, Lian Lian

“…This is the first time that ACO has been directly used for MPPT in a PV system. As other related evolutionary algorithms can also be applied to the MPPT in a similar way, a uniform implementation scheme for other evolutionary algorithms under several different PV array topologies is proposed. …”
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Non-newtonian fluids and droplets in microchannels by Huang, Yi

“…Flow conditions of experiments, microchannel geometries, and AC electric field parameters have been implemented systematically. The influences of these variables were analyzed. …”
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会话分析研究 ：“就” 作为回应开头单位的互动会话功能 = Conversation Analysis : “jiu” as a turn-initial object of a response in Mandarin conversation by 林美琦 Lim, Maggie Meiqi

“…In Conversation Analysis, we argue that the turn-initial object of a response can often have its own communicative function – it has been proven through extensive research that respondents do make use of these small objects to express their stance or attitude towards the prior turn. …”
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