Case Report: Concurrent transcatheter aortic and mitral valve replacement for symptomatic concomitant aortic and mitral valve stenoses by Bussmann, BM, Dawkins, S, Newton, J, Cahill, T

“…We present a case of a 76-year-old patient with concomitant severe aortic valve stenosis and severe mitral valve stenosis who underwent concurrent TAVI and transcatheter mitral valve replacement. …”

Biorobotic hybrid heart as a benchtop cardiac mitral valve simulator by Park, Clara, Singh, Manisha, Saeed, Mossab Y., Nguyen, Christopher T., Roche, Ellen T.

“…In this work, we developed a high-fidelity beating heart simulator that provides accurate mitral valve pathophysiology. The benchtop platform is based on a biorobotic hybrid heart that combines preserved intracardiac tissue with soft robotic cardiac muscle providing dynamic left ventricular motion and precise anatomical features designed for testing intracardiac devices, particularly for mitral valve repair. …”
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Physicochemical and in-vitro release studies of liponanocapsules by Tan, Dulcia Wei Ni.

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In vitro reconstitution of telomeric mono-nucleosomes by Tiu, Charles Kevin Dee

“…In this report, I endeavor to demonstrate telomeric mono-nucleosome reconstitution in vitro with a defined-length telomeric 145-bp DNA (telo-145) and in vitro refolded human histone octamer by salt-gradient deposition – a method currently being optimized in our laboratory. …”
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Alcohol septal ablation for hypertrophic obstructive cardiomyopathy: do mitral valve leaflet length, septal thickness, or sex affect the outcome? by Mustafic, Mesud, Jandér, Rebecka, Marlevi, David, Rickenlund, Anette, Rück, Andreas, Saleh, Nawzad, Abdi, Sam, Eriksson, Maria J., Damlin, Anna

“…BSWT ≥ 23 mm (n = 13, 12%) was associated with remaining LVOTO at follow-up (p = 0.004). Elongated mitral valve leaflet length (either AML or PML) was present in 125 (90%) patients. …”
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Composite hydrogels in three-dimensional in vitro models by Zhao, Zhitong, Vizetto-Duarte, Catarina, Moay, Zi Kuang, Setyawati, Magdiel Inggrid, Rakshit, Moumita, Kathawala, Mustafa Hussain, Ng, Kee Woei

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In-vitro fractional flow reserve of coronary artery by Kwa, June Li Jun

“…The objective of this project is to explore the possibility of using a non-invasive method to measure the level of stenosis in the patient’s arteries using a in-vitro set up. In this project, we will be making use of 3 different 3D printed coronary arteries at the stroke volume of 71.6ml. …”
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In-vitro fractional flow reserve of coronary artery by Qamaruz Zaman Ali

“…This project aims to firstly, study the possibility of using an external in-vitro test setup to simulate human hemodynamics. …”
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Investigating follicle development using in vitro technologies by Lo, B

“…In this thesis, with the aim of moving towards a clinical treatment, we assessed follicle development in ROs <em>in vitro</em> and progressed to using the technique with human tissues. …”

In vitro protein (BSA) delivery studies in mesostructured bioceramics by Aw, Siew Sim

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Transcriptomic profiling of polymicrobial biofilm dynamics on catheters in Vitro by Lai, Valerie Jia Hui

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In vitro and in silico investigation of TRPC3 mechanism and dynamics by Collingridge, J

“…Using a combination of in silico and in vitro approaches, this thesis proposes the vanilloid-like transmembrane domain S4/5 pocket as the binding site of a novel TRPC3 inhibitor, GSK-2820986A (GSK-986). …”

Rifaximin potentiates clarithromycin against Mycobacterium abscessus in vitro and in zebrafish by Goh, Boon Chong, Larsson, Simon, Dam, Linh Chi, Ling, Sharon Yan Han, Chua, Patrina Wei Lin, Abirami, R., Singh, Samsher, Ong, Ernest Jun Long, Teo, Jeanette W. P., Ho, Peiying, Ingham, Philip William, Pethe, Kevin, Dedon, Peter C.

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Investigation on in vitro degradation of poly (L-lactide) for biomedical applications by Ting, Hie King.

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Characterization of ubiquitin-activated DNA-protein crosslink repair in vitro by Zhu, X

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Antidiabetic activity of Curculigo latifolia extracts in vitro and in vivo studies by Ishak, Nur Akmal

“…In the present study, antidiabetic properties of C. latifolia in cell lines (in vitro) and in diabetic-induced rats were determined. …”
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Lipid-coated hybrid nanoparticles for enhanced bacterial biofilm penetration and antibiofilm efficacy by Lee, Hiang Wee, Kharel, Sharad, Loo, Joachim Say Chye

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Mechanistic modeling of in vitro transcription incorporating effects of magnesium pyrophosphate crystallization by Stover, Nathan Merica, Ganko, Krystian, Braatz, Richard D

“…The in vitro transcription (IVT) reaction used in the production of messenger RNA vaccines and therapies remains poorly quantitatively understood. …”
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Deep learning methods to study structurally heterogeneous macromolecules in vitro and in situ by Powell, Barrett M.

“…Most such structural insights use techniques that strip the macromolecule of its cellular context (i.e., in vitro) and, subsequently, report a single average structure. …”
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In vitro reconstitution of liquid-liquid phase separation in regulating gene transcription by Gan, Jia Yun

“…In this study, we are interested in determining the conditions where nuclear transcription factor TF9 and TF9-BFP will undergo LLPS in vitro, and the effects of the addition of TF11 and TF11-mcherry on TF9 phase separation. …”
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