Effects of transport inhibitors on the cellular uptake of liposomes from mycobacterium smegmatis by human monocytes dendritic cells by Nordin, Nor Asyikin

“…Supernatant will be collected to measure the cytokine level by ELISA. Therefore, in this proposed study, we are going to fill up the gaps by investigating the uptake mechanisms of liposomes-Msmeg as a potent lipid-based vaccine by DCs from PBMC in healthy individuals.…”
Get full text

Supermind Ideator: How Scaffolding Human-AI Collaboration Can Increase Creativity by Heyman, Jennifer, Rick, Steven, Giacomelli, Gianni, Wen, Haoran, Laubacher, Robert, Taubenslag, Nancy, Knicker, Max, Jeddi, Younes, Ragupathy, Pranav, Curhan, Jared, Malone, Thomas

Get full text

Global monitoring of volcanic SO2 degassing with unprecedented resolution from TROPOMI onboard Sentinel-5 Precursor by Barrington, Charlotte, Taisne, Benoit, Theys, N., Hedelt, P., De Smedt, I., Lerot, C., Yu, H., Vlietinck, J., Pedergnana, M., Arellano, S., Galle, B., Fernandez, D., Carlito, C. J. M., Delgado-Granados, H., Loyola, D., Van Roozendael, M.

“…We report here the first volcanic SO2 measurements from the hyperspectral TROPOspheric Monitoring Instrument (TROPOMI) launched in October 2017 onboard the ESA’s Sentinel-5 Precursor platform. Using the operational processing algorithm, we explore the benefit of improved spatial resolution to the monitoring of global volcanic degassing. …”
Get full text
Get full text

Towards a Single Bio-molecule Detector Based on CMOS Nanofluidic Platform by Zikrallah, Ahmed S.

“…Ideally, we would be able to continuously monitor the secretome of these cell therapies as they are transformed and expanded in manufacturing.However, state-of-theart techniques for monitoring typically low concentrations of cytokines require either Mass Spectroscopy (MS) or immunoassays like Enzyme-linked Immunosorbent Assay (ELISA). We propose the use of CMOS technology to build a proteomic platform with a single biomolecule resolution. …”
Get full text
Get full text

Skin dendritic cell and T cell activation associated with dengue shock syndrome by Duyen, Huynh Thi Le, Cerny, Daniela, Trung, Dinh The, Pang, Jassia, Velumani, Sumathy, Toh, Ying Xiu, Qui, Phan Tu, Hao, Nguyen Van, Simmons, Cameron, Haniffa, Muzlifah, Wills, Bridget, Fink, Katja

“…We analyzed cell subsets by flow cytometry, and soluble mediators and antibodies by ELISA; the percentage of migratory CD1a+ dermal DCs was significantly decreased in the DSS patients, and skin CD8+ T cells were activated, but there was no accumulation of dengue-specific antibodies. …”
Get full text
Get full text

The chronic cerebral hypoperfusion model induces proinflammatory cascades in Alzheimer's disease by Abedi, Zahra, Basri, Hamidon, Hassan, Zurina, Inche Mat, Liyana Najwa, Khaza’ai, Huzwah, Mohd Ali, Razana

“…The gene expression levels of cathepsin B, NLRP3, an apoptosis-associated speck-like protein containing a caspase recruitment domain (ASC), and caspase-1 were analysed using real-time PCR, while the expression levels of the inflammatory cytokines were estimated using the ELISA method. Structural damage to the hippocampus was assessed using hematoxylin and eosin (HE) staining. …”
Get full text

Reinforcement learning for an efficient and effective malware investigation during cyber Incident response by Dunsin, Dipo, Ghanem, Mohamed Chahine, Ouazzane, Karim, Vassilev, Vassil

“…Future work will incorporate more advanced RL algorithms and large language models (LLMs) to further enhance the effectiveness of malware forensic analysis.…”
Get full text
Get full text

MindScape Study: Integrating LLM and Behavioral Sensing for Personalized AI-Driven Journaling Experiences by Nepal, Subigya, Pillai, Arvind, Campbell, William, Massachi, Talie, Heinz, Michael, Kunwar, Ashmita, Choi, Eunsol Soul, Xu, Xuhai "Orson", Kuc, Joanna, Huckins, Jeremy, Holden, Jason, Preum, Sarah M., Depp, Colin, Jacobson, Nicholas, Czerwinski, Mary, Granholm, Eric, Campbell, Andrew

“…MindScape pioneers a novel approach to AI-powered journaling by integrating passively collected behavioral patterns such as conversational engagement, sleep, and location with Large Language Models (LLMs). This integration creates a highly personalized and context-aware journaling experience, enhancing self-awareness and well-being by embedding behavioral intelligence into AI. …”
Get full text

The MALINA oceanographic expedition : how do changes in ice cover, permafrost and UV radiation impact biodiversity and biogeochemical fluxes in the Arctic Ocean? by Massicotte, P., Amon, R. M. W., Antoine, D., Archambault, P., Balzano, S., Bélanger, S., Benner, R., Boeuf, D., Bricaud, A., Bruyant, F., Chaillou, G., Chami, M., Charrière, B., Chen, J., Claustre, H., Coupel, P., Delsaut, N., Doxaran, D., Ehn, J., Fichot, C., Forget, M. H., Fu, P., Gagnon, J., Garcia, N., Gasser, B., Ghiglione, J. F., Gorsky, G., Gosselin, M., Gourvil, P., Gratton, Y., Guillot, P., Heipieper, H. J., Heussner, S., Hooker, S. B., Huot, Y., Jeanthon, C., Jeffrey, W., Joux, F., Kawamura, K., Lansard, B., Leymarie, E., Link, H., Lovejoy, C., Marec, C., Marie, D., Martin, J., Martín, J., Massé, G., Matsuoka, A., McKague, V., Mignot, A., Miller, W. L., Miquel, J. C., Mucc,i A., Ono, K., Ortega-Retuerta, E., Panagiotopoulos, C., Papakyriakou, T., Picheral, M., Prieu,r L., Raimbault, P., Ras, J., Reynolds, R. A., Rochon, A., Rontani, J. F., Schmechtig, C., Schmidt, S., Sempéré, R., Shen, Y., Song, G., Stramski, D., Tachibana, E., Thirouard, A., Tolosa, I., Tremblay, J. E., Vaïtilingom, M., Vaulot, Daniel, Vaultier, F., Volkman, J. K., Xie, H., Zheng, G., Babin, M.

Get full text

Seroepidemiology of COVID-19 in pregnant women and their infants in Uganda and Malawi across multiple waves 2020-2022 by Hookham, L, Cantrell, L, Cose, S, Freyne, B, Gadama, L, Imede, E, Kawaza, K, Lissauer, S, Musoke, P, Nankabirwa, V, Sekikubo, M, Sommerfelt, H, Voysey, M, PeriCOVID Consortium, Le Doare, K

“…A nasopharyngeal swab was taken from mothers at enrolment for RT-PCR confirmation of SARS-CoV-2 infection, and maternal and cord blood samples were tested for SARS-CoV-2 antibodies using Wantai and Euroimmune ELISA. The primary outcome was seroprevalence of SARS-CoV-2 antibodies in maternal blood, reported as the proportion of seropositive women by study site and wave of COVID-19 within each country. …”

Effects of ifenprodil treatment on pain behaviour, inflammation, and nociceptive responses in the spinal cord of complete freund’s adjuvant-induced chronic polyarthritis rat by Noh, Ain’ Sabreena Mohd

“…Histopathological examination was performed on the ipsilateral ankle joint while the lumbar region of the spinal cord (L4-L5) was collected for ELISA, immunohistochemistry and RT-qPCR analyses. …”
Get full text

Cytotoxicity assessment of α helix Antarctic yeast oriented antifreeze peptide (Afp1m) on M. dunni (Clone III8C) cells by Khan, Muhammad Shuaib, Abdul Rahman, Mohd Basyaruddin, Abu Bakar, Mohd Zuki, Noordin, Mohammed Mustapha, Ullah, Shakeeb, Abdul Abubakar, Adamu, Rehman, Saifur, Saddiqua, Aisha, Mohammad Yusof, Loqman

“…The findings of this work indicate that Afp1m exhibits cryoprotective properties without inducing toxicity when used for the cryopreservation of M. dunni (Clone III8C) cells. were cul t ured wi t h 10% FBS (Foet al Bovine Serum) using an Elisa reader and in medium containing various amounts (10, 5, 2, 1 and 0.5 mg/mL) of Afp1m, the control group (10% FBS) displayed varying survival percentages (78.86 ± 10.17%, 88.38 ± 3.19%, 88.75 ± 7.19 %, 90.61 ± 7.11%, 91.19 ± 4.52%, and 100.00 ± 0.0 %) throughout 24 hr. …”
Get full text

Secure Computation in Decentralized Systems by Zyskind, Guy

“…Secure Inference with private retrieval: Lastly, the thesis explores how Large Language Models (LLMs) can perform secure inference while retrieving data from private, distributed databases. …”
Get full text
Get full text

PESI: paratope-epitope set interaction for SARS-CoV-2 neutralization prediction by Wan, Zhang, Lin, Zhuoyi, Rashid, Shamima, Ng, Shaun Yue Hao, Yin, Rui, Senthilnath, J., Kwoh, Chee Keong

“…In particular, large language models (LLMs) based method predicts neutralization using Fv sequences of antibody and antigen. …”
Get full text

3D printed magnetic digital microfluidics for biomedical applications by Kanitthamniyom, Pojchanun

“…Here, the detection of hepatitis B surface antigen using enzyme-linked immunosorbent assay (ELISA) was demonstrated on the new platform for the potential diagnostics of hepatitis. …”
Get full text

Leucine-rich α-2-glycoprotein 1 suppresses endothelial cell activation through ADAM10-mediated shedding of TNF-α receptor by Pang, Kuin Tian, Ghim, Mean, Liu, Chenghao, Tay, Hui Min, Fhu, Chee Wai, Chia, Rui Ning, Qiu, Beiying, Sarathchandra, Padmini, Chester, Adrian H., Yacoub, Magdi H., Wilkinson, Fiona L., Weston, Ria, Warboys, Christina M., Hou, Han Wei, Weinberg, Peter D., Wang, Xiaomeng

“…LRG1 in endothelial cells (ECs) of arteries and serum of patients with critical limb ischemia (CLI) was assessed by immunohistochemistry and ELISA, respectively. LRG1 expression in sheared and tumor necrosis factor-α (TNF-α)-treated ECs was analyzed. …”
Get full text

From public health to AI safety: improving machine learning approaches by collecting, selecting, or reducing the need for high-quality data by Brauner, J

“…</p> <br> <p>First, we tackle AI misuse and misalignment by building a detector for “lies”---which we define as particular types of falsehoods---output by large language models (LLMs). This endeavour is complicated by the difficulty in acquiring appropriate training data. …”

Magnetic nanochain enabled microarray and microfluidic bioassays by Xiong, Qirong

“…The magnetic dynamic nanomixers were expected to find widespread uses in on-surface bioassays that suffer from diffusion limitation, such as microfluidic assays, enzyme-linked immunosorbent assay (ELISA), and heterogeneous catalysis. Finally, we used this dual-functional magnetic nanochains in microfluidic bioassay. …”
Get full text
Get full text

Development of human enterovirus 71 nano calcium phosphate adjuvanted candidate vaccine for parenteral and mucosal delivery by Saeed Ahmed, Mohamed Ibrahim

“…The samples were examined for the presence of HEV71 specific IgG and IgA antibody classes in the serum and saliva using an in-house developed ELISA assay. The in vitro delivery of adjuvant loaded polymeric carrier offered an improved and sustained release of the nano-adjuvant encapsulated in chitosan but not alginate, due to the reversibility of adjuvant-polymer interaction. …”
Get full text

Evaluation of diabetic wound healing properties of moringa oleifera lam using in vitro and in vivo wound models by Muhammad Amali, Abubakar

“…Proinflammatory cytokines analyses were performed using ELISA, Western blotting and immunohistochemistry techniques. …”
Get full text