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161
Translation termination mechanism studied by solution state NMR
Published 2012“…In eukaryotes, class-I release factor (eRF1) directly recognizes all three stop-codons in the A site on the small ribosomal subunit and stimulates peptide release. …”
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Thesis -
162
Automated sample preparation systems for medical diagnostics
Published 2014“…At the heart of all these applications is the procedure of sample preparation to extract nucleic acids of interest from organisms for subsequent analyses. …”
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Thesis -
163
European biologic training course for type 2 inflammation by EUFOREA in 2024: key facts and lessons learned
Published 2024“…EUFOREA is an international non-for-profit organization forming an alliance of all stakeholders dedicated to reducing the prevalence and burden of chronic respiratory diseases through the implementation of optimal patient care via educational, research, and advocacy activities. …”
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The Accident /
Published 2015“…Taking place over the course of twenty-four hours, The Accident draws on the rich worlds of publishing, politics and international spies to tell a suspenseful tale of intrigue in the vein of John Grisham and Laura Lippman. …”
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166
Synthesis of densely functionalized pyrroles from unprotected carbohydrates
Published 2023“…The activity of pyrrole-based drugs is tuned with the type of substituents on the pyrrole core and on the substitution pattern on the core pyrrole ring. …”
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Thesis-Doctor of Philosophy -
167
Collective synthesis of 4-Hydroxy-2-pyridone alkaloids and their antiproliferation activities
Published 2014“…Hence, this approach could potentially contribute to the synthesis of bioactive small-molecule libraries as well as drug discovery.…”
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168
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170
Discovery of stabilized functional mutants of human aquaporin 1
Published 2016“…Aquaporins (AQPs) are essential water channel proteins found in the cell membranes of all forms of life. In this project, a random mutagenesis library for human aquaporin 1 (hAQP1) is generated and screened for functional mutants. …”
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Final Year Project (FYP) -
171
Studies towards the synthesis of bioactive natural products and development of new synthetic methods
Published 2017“…It has been estimated that more than half of all approved drugs, from the period 1981 to 2014, are either natural products or their derivatives. …”
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Thesis -
172
Mitigating marine megafauna captures in fisheries
Published 2020“…</p> <p>Throughout the fishery case study, I draw on established decision-making processes to better understand the conservation issue at hand and to develop an understanding of what is necessary to empirically calculate net outcomes in data-poor fishing systems using the proposed framework. …”
Thesis -
173
Compressible hollow microlasers in organoids for high-throughput and real-time mechanical screening
Published 2024“…Here, we introduce biocompatible and compressible hollow microlasers that realize all-optical assessment of cellular stress within organoids. …”
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Journal Article -
174
Childhood bullying and mental health: understanding risk, resilience, and the role of anti-bullying interventions
Published 2023“…The best approaches to study causal effects are natural experiments, longitudinal data, and randomised controlled trials of interventions. This thesis combines all these approaches to examine the relationship between bullying and mental health across different contexts.…”
Thesis -
175
Self-propelled autonomous Mg/Pt janus micromotor interaction with human cells
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Journal Article -
176
Dearomatization of (hetero)arenes through photodriven interplay between polysulfide anions and formate
Published 2023Get full text
Journal Article -
177
Integrate Traditional Chinese Medicine (TCM) into cognitive behavioural therapy to treat postpartum depression in Chinese culture contexts.
Published 2013“…As in Chinese cultures, it is believed that any kind of drug has certain degree of side effects. In the end, all different kinds of factors have lead to the fact that most women suffering from postpartum disorders or depression left unwell treated. …”
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Final Year Project (FYP) -
178
Predicting rifampicin resistance in M. tuberculosis using machine learning informed by protein structural and chemical features
Published 2025“…We have trained a learning models with the aim of complementing genetics-based drug susceptibility testing.</p> <br> <p><strong>Methods:</strong> We built a Test+Train dataset comprising 219 susceptible mutations. …”
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179
Sharing is caring? International Society for Pharmacoepidemiology review and recommendations for sharing programming code
Published 2024“…<p><strong> Methods: </p></strong>We conducted a literature review identifying all studies published in Pharmacoepidemiology and Drug Safety (PDS) between 2017 and 2022. …”
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180
Tumor-targeted nano-assemblies for energy-blocking cocktail therapy in cancer
Published 2024Get full text
Journal Article