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4961
Biomolecular hydration in protein-protein interaction, protein stability and aggregation and lead optimization : computational studies
Published 2017“…Combining systematic data mining and quantification of these hydration sites using „JAL‟ a novel two water-bridge motif is identified that appears to be central to the nucleotide recognition by eIF4E. This is a novel finding and I believe will facilitate the design of specific inhibitors of eIF4E which is a therapeutic target in oncology. …”
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Thesis -
4962
Immunoprofiling of drug-resistant epilepsy with a focus on glutamic acid decarboxylase 65 antibodies
Published 2021“…Pain was reported as a seizure trigger in three patients, an unusual finding in epilepsy.</p> <p>Cytokine concentrations measured by a multiplex bead-based immunoassay combined with flow cytometry showed GAD65 autoantibody-positive DRE patient plasmas were enriched for IL1b, IL4, IL10, IL15 and TNFa, consistent with multifaceted immune system involvement. …”
Thesis -
4963
Exciton Dynamics and Anisotropy in 2D Metal Organochalcogenolate Semiconductors
Published 2024“…This divergence in excitonic properties is attributed to the semi 1D Ag chains in AgSePh-F₂(2,3), in contrast to hexagonal 2D Ag network in AgSePh. This finding can be generalized to other blue-emitting 2D AgSePh-R compounds which exhibit either AgSePh-like or AgSePh-F₂(2,3)-like absorption spectra. …”
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Thesis -
4964
Vision language representation learning
Published 2023“…Vision and language tasks have garnered increasing research attention in recent years, finding extensive applications in commercial software such as Microsoft Office, Amazon cloud services, and the iOS photo app. …”
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Thesis-Doctor of Philosophy -
4965
Multi-scale and multiphase modeling of abrasive flow machining process with experimental validation
Published 2023“…AFM studies commonly lump this abrasion action either by empirical model or simplified shapes with simplified force-indentation equation therefore, the abrasion action details are missing. Here, the study finds out the particle forces, surface deformation, and MR mechanisms. …”
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Thesis-Doctor of Philosophy -
4966
话语标记 “可是” 在马来西亚华语会话中的语用功能 = Pragmatic functions of discourse marker “Keshi” in conversational Malaysian Mandarin
Published 2016“…Previous research have investigated extensively the truth value semantics of “keshi” based on written Mandarin, however, this paper finds that the various uses of “keshi” in natural conversations can hardly be explained with such semantics. …”
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Final Year Project (FYP) -
4967
Essays on multi-echelon inventory control
Published 2016“…Optimal inventory control policies for two-level distribution systems are notoriously complicated because of the stock allocation problem when shortage occurs at the warehouse. However, finding warehouse stock allocation policies that are optimal or near-optimal and easy to implement is of practical importance. …”
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Thesis -
4968
Investigating the role of astrocytes in Parkinson's disease pathogenesis in GBA- N370S iPSC-derived neural cultures
Published 2024“…</p> <p>Furthermore, bulk RNAseq data of control iASTROs treated with inflammatory cytokines and PFFs for 24h revealed very extensive transcriptomic changes in response to inflammatory cytokines but not PFFs, a finding that was verified with subsequent immunocytochemistry and RT-qPCR experiments conducted after 24h and 7 days of treatment. …”
Thesis -
4969
Pregnant women admitted to hospital with covid-19 in 10 European countries: individual patient data meta-analysis of population based cohorts in International Obstetric Survey Syst...
Published 2024“…</p> <p><strong>Conclusions</strong> Population based surveillance in 10 European countries during the first 10 months of the covid-19 pandemic showed variations in the risk of hospital admissions for covid-19 in pregnant women. This finding indicates that national public health policies likely had a substantial and previously unrecognised role in protecting pregnant women. …”
Journal article -
4970
Harvest age and planting density effects on yield and quality of two kenaf (Hibiscus cannabinus l.) Varieties for fibre and animal feed
Published 2015“…This was based from the finding that MHC 123 and V 36 were higher in dry matter yield, bast yield, core yield at density of 444,400 plants ha-1. …”
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Thesis -
4971
Advancements in Management Science: Applications to Online Retail, Healthcare, and Non-Profit Fundraising
Published 2024“…Surprisingly, the analysis also finds evidence which supports increased efficacy of first line agents relative to second-line antibiotics, which are of broader spectrum, albeit the effect difference is smaller compared to the comparison between first-line antibiotics and alternatives. …”
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Thesis -
4972
Advanced attack and defense techniques in machine learning systems
Published 2019“…For multiple-credential scenarios, we formulate it as a bilevel optimization problem for finding the optimal defense strategy and then reduce it to a single level optimization problem called PEMS using complementary slackness conditions. …”
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Thesis -
4973
Enhancement of photoacoustic imaging systems for biomedical applications
Published 2021“…Cross-sectional imaging at multiple depths was performed to show the capability of this system for finding the relative depth of different vessels and organs in a growing embryo. …”
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Thesis-Doctor of Philosophy -
4974
Localized structural and bulk effects in hybrid organic-inoraginc perovskites
Published 2021“…Through a combination of steady state photoinduced absorption, transient absorption and transient photocurrent measurements, this chapter has confirmed the existence of theoretically predicted polaronic states in MAPbI3 which finds its origins in the ‘soft’ lead – iodide bond. …”
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Thesis-Doctor of Philosophy -
4975
Modelling, exploration and optimization of hardware accelerators for deep learning applications
Published 2023“…Deep learning has achieved popularity due to its improved prediction accuracy, and it finds widespread use in large data processing applications. …”
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Thesis-Doctor of Philosophy -
4976
Two-dimensional metal-organic frameworks for gas sensing
Published 2024“…This method successfully generates uniform distributions of the desired MOFs in situ on glass, gold, paper and cotton substrates, and is therefore anticipated to be a significant finding in the fields of wearable electronics, chemiresistive sensors and capacitor devices.…”
Thesis -
4977
The evolution and fate of waste plastics in landfills subject to physical and biochemical processes — implications for microplastics
Published 2024“…Nonetheless, a substantial volume of plastics becomes plastic waste (PW), with a significant portion finding its way to landfills. Microplastics (MPs), a recently identified group of pollutants with dimensions below 5 mm, raise apprehensions about potential toxicity and their ability to transport other contaminants like heavy metals through adsorption and dissociation mechanisms. …”
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Thesis-Doctor of Philosophy -
4978
Antimicrobial activity, phytochemical and toxicity analyses of salam [Syzygium polyanthum (Wight) Walp.] leaf extract and its application in food
Published 2018“…Physical characteristics in term of colour, texture and odour, all the treated samples until the highest concentration of extract [5% (v/v)] showed not significantly different and this finding also parallel to sensory acceptability where 5% of extract was accepted by the panelists. …”
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Thesis -
4979
Neural combinatorial optimization: from routing to integer programming
Published 2022“…However, classic heuristic methods severely depend on the design of hand-crafted rules for every specific COP, which could limit their performance in practice. Also, finding effective rules in heuristics is non-trivial and often needs massive expertise and tuning work. …”
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Thesis-Doctor of Philosophy -
4980
Methods of growth and transfer of carbon nanotubes onto substrates for advanced electrical and electronic applications
Published 2023“…Subsequently, the influence of various growth parameters such substrate oxide thickness, amount of water vapor and etching time on efficiency of delamination was evaluated and optimized to yield wafer-scale free-standing VACNT, without requiring any form of mechanical handling. A significant key finding of the delamination study is that the SiO2 surface plays a crucial role for large scale self-delamination of VACNT. …”
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Thesis-Doctor of Philosophy