Using machine learning to discover candidate localised transcripts from microscopy and genome-wide bioinformatics data by Kiourlappou, M

“…Next, I present the innovative pipeline I use to systematically manage the output raw microscopy images and to create figures (approximately 1400 figures). …”

Cryo-electron microscopy structure of the Mycobacterium tuberculosis cytochrome bcc:aa₃ supercomplex and a novel inhibitor targeting subunit cytochrome cI by Mathiyazakan, Vikneswaran, Wong, Chui Fann, Harikishore, Amaravadhi, Pethe, Kevin, Grüber, Gerhard

Get full text

Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation by Vasudevan, Subhash G., Peng, Minhua, Swarbrick, Crystall Marie Dawn, Chan, Kitti Wing-Ki, Luo, Dahai, Zhang, Wei, Lai, Xiaoping, Li, Geng

Get full text
Get full text

Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals by Goh, Yun Shan, Rouers, Angeline, Fong, Siew-Wai, Zhuo, Nicole Ziyi, Hor, Pei Xiang, Loh, Chiew Yee, Huang, Yuling, Neo, Vanessa Kexin, Kam, Isaac Kai Jie, Wang, Bei, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Lee, Raphael Tze Chuen, Pada, Surinder, Sun, Louisa Jin, Ong, Desmond Luan Seng, Somani, Jyoti, Lee, Eng Sing, Maurer-Stroh, Sebastian, Wang, Cheng-I., Leo, Yee Sin, Ren, Ee Chee, Lye, David C., Young, Barnaby Edward, Ng, Lisa F. P., Renia, Laurent

Get full text

Navigating the real world: a grounded theory-based exploration of autistic adolescents identity formation in Marcelo in the real world by Yang, Shuo, Mani, Manimangai, Omar, Noritah

“…The use of grounded theory methodology enables a full examination of Marcelo's experiences and the fundamental mechanisms guiding the development of his identity. …”
Get full text

Three Provocations for Civic Crowdfunding by Davies, Rodrigo

“…This paper considers civic crowdfunding — the use of crowdfunding for projects that produce community or quasipublic assets — and argues that its emergence demands a fresh set of questions and approaches. The work draws on critical case studies constructed through fieldwork in the US, the UK and Brazil, and a discourse analysis of civic crowdfunding projects collected from platforms by the author. …”
Get full text

SP.236 / ES.SP236 Exploring Pharmacology, Spring 2009 by Gusman, Mariya, Fallows, Zak

“…From Abilify to Zyrtec, the world is full of interesting drugs. Such substances have cured diseases, started wars, and ended careers. …”
Get full text

Interventions for managing skeletal muscle spasticity following traumatic brain injury by Synnot, Anneliese, Chau, Marisa, Pitt, Veronica, O'Connor, Denise, Gruen, Russell Lindsay, Wasiak, Jason, Clavisi, Ornella, Pattuwage, Loyal, Phillips, Kate

“…The four studies without useable results were funded by pharmaceutical or medical technology companies. It was difficult to draw conclusions about the effectiveness of these interventions due to poor reporting, small study size and the fact that participants with TBI were usually only a proportion of the overall total. …”
Get full text
Get full text

Chitosan nanofibrous scaffold with graded and controlled release of ciprofloxacin and BMP-2 nanoparticles for the conception of bone regeneration by Zhang, Sihan, Zhao, Guanglei, Mahotra, Manish, Ma, Shiyuan, Li, Wenrui, Lee, Hiang Wee, Yu, Hong, Sampathkumar, Kaarunya, Xie, Denghui, Guo, Jinshan, Loo, Joachim Say Chye

Get full text

The effect of regularly dosed paracetamol versus no paracetamol on renal function in Plasmodium knowlesi malaria (PACKNOW) : study protocol for a randomised controlled trial by Cooper, Daniel J., Plewes, Katherine, Grigg, Matthew J., Rajahram, Giri S., Piera, Kim A., William, Timothy, Chatfield, Mark D., Yeo, Tsin Wen, Dondorp, Arjen M., Anstey, Nicholas M., Barber, Bridget E.

“…The inexpensive and widely available drug paracetamol inhibits CFHb-induced lipid peroxidation via reduction of ferryl haem to the less toxic Fe3+ state, and has been shown to reduce oxidative damage and improve renal function in patients with sepsis complicated by haemolysis as well as in falciparum malaria. …”
Get full text
Get full text

Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study... by Dyson, ZA, Ashton, PM, Khanam, F, Chunga Chirambo, A, Shakya, M, Meiring, JE, Tonks, S, Karkey, A, Msefula, C, Clemens, JD, Dunstan, SJ, Baker, S, Dougan, G, Pitzer, VE, Basnyat, B, Qadri, F, Heyderman, RS, Gordon, MA, Holt, KE, Pollard, AJ, STRATAA Study Group

“…S Typhi genotype 4.3.1 (H58) was common in all sites, but with different dominant variants (4.3.1.1.EA1 in Blantyre, 4.3.1.1 in Dhaka, and 4.3.1.2 in Kathmandu). …”

Colloidal quantum dot light-emitting diode architectures for high performance by Leck, Kheng Swee

“…QD-LEDs have made great progress in terms of device performance over the years and there is room for further improvement. With all these findings and demonstrations in this thesis, we conclude that QD-LEDs hold great promise for potential applications in lighting and displays…”
Get full text

Mitochondrial dysfunction in Down Syndrome: from pathology to therapy by Tan, Kai-Leng, Lee, Han-Chung, Cheah, Pike-See, Ling, King-Hwa

“…Mitochondrial dysfunctions have been described in Down syndrome (DS) caused by either partial or full trisomy of chromosome 21 (HSA21). Mitochondria play a crucial role in various vital functions in eukaryotic cells, especially in energy production, calcium homeostasis and programmed cell death. …”
Get full text

Carbon nanomaterial/thermoplastic polyurethane composites for sports application : preparation, characterization and simulation by Jing, Qifei

“…Regarding the thermal stability, PU filled with 1 wt% FGO showed the largest extent of improvement. …”
Get full text

Metformin degradation with combined Ozone/UV/H2O2 process by Fujinami, Shoko Carissa

“…Metformin is a commonly used drug to treat Type 2 diabetic patients. As the number of diabetic patients globally has increased from 108 million in 1980 to 422 million in 2014, it can be seen that diabetes is a common form of illness and in Singapore, there is about 1 in 10 people suffering from diabetes (Lai, 2015). …”
Get full text

Efficacy and safety of tirzepatide for treatment of overweight or obesity. A systematic review and meta-analysis by Tan, Bryan, Pan, Xin-Hui, Chew, Jocelyn Han Shi, Goh, Rachel Sze Jen, Lin, Chaoxing, Anand, Vickram Vijay, Lee, Ethan Cheng Zhe, Chan, Kai En, Kong, Gwyneth, Ong, Christen En Ya, Chung, Charlotte Hui, Young, Dan Yock, Chan, Mark Y., Khoo, Chin Meng, Mehta, Anurag, Muthiah, Mark Dhinesh, Noureddin, Mazen, Ng, Cheng Han, Chew, Nicholas W. S., Chin, Yip Han

Get full text

Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021 by Vollset, SE, Ababneh, HS, Abate, YH, Lacey, BWH, GBD 2021 Forecasting Collaborators

“…All analyses were done at the cause-specific level so that only risk factors deemed causal by the GBD comparative risk assessment influenced future trajectories of mortality for each disease. …”

Effect of metabolite and temperature on artificial human sweat characteristics over a very wide frequency range (400 MHz–10.4 GHz) for wireless hydration diagnostic sensors by Lubangakene, Innocent, Virdee, Bal Singh, Jayanthi, Renu, Ganguly, Priyanka

“…As a result, analysis of electrolytes in this biofluid is gaining traction in the development of non-invasive sweat diagnostics to determine level of dehydration, cystic fibrosis and illicit drugs. This paper presents a wireless measurement modality of permittivity properties of sweat of different metabolite concentration levels exemplifying the full spectrum of human sweat. …”
Get full text

Multi-hand finger counting hardware/software system with Xillybus IP core on Xilinx Zynq by Lee, Fabian Jin Wei

“…Embedded reconfigurable systems display promising advantages: higher performance while drawing lower power with better reliability and scalability. …”
Get full text

Human centric sensing by android phones for vehicular applications by Bose, Subhodeep

“…For the purpose of this project, an android based smartphone application for sensing based functionalities was developed as part of an ongoing PhD project on ‘Intelligent Parking’ for the NTU-BMW Future Mobility Research Lab. The project draws motivation from the fact that human-centric sensing using smartphones is an area full of prospects and opportunities. …”
Get full text