Renal-clearable molecular probe for near-infrared fluorescence imaging and urinalysis of SARS-CoV-2 by Liew, Si Si, Zeng, Ziling, Cheng, Penghui, He, Shasha, Zhang, Chi, Pu, Kanyi

Get full text

White-light-responsive prussian blue nanophotonic particles for effective eradication of bacteria and improved healing of infected cutaneous wounds by Chakraborty, Nayanika, Jha, Diksha, Singh, Vijay Pal, Kumar, Pradeep, Verma, Navin Kumar, Gautam, Hemant Kumar, Roy, Indrajit

Get full text

Organic solvent-assisted control of hydrogel structures and properties by Zhou, Quan

“…Hydrogels are three-dimensional (3D) cross-linked polymeric networks containing a significant amount of water and have found their applications in various fields, including tissue engineering, drug delivery, etc. However, major limitations still exist for hydrogels, especially their mechanical weakness, which limits their use in load-bearing applications. …”
Get full text

Gametocyte carriage in uncomplicated plasmodium falciparum malaria following treatment with artemisinin combination therapy: a systematic review and meta-analysis of individual pat... by Abdulla, S, Achan, J, Yeka, A, D'Alessandro, U, Adam, I, Alemayehu, B, Allan, R, Temu, E, Allen, E, Barnes, K, Anvikar, A, Valecha, N, Arinaitwe, E, Ashley, E, Carrara, V, McGready, R, Nosten, F, Lee, S, White, N, Asih, P, Awab, G, Dondorp, A, Fanello, C, Woodrow, C, Dahal, P, Guerin, P, Humphreys, G, Moreira, C, Nsanzabana, C, Price, R, Sibley, C, Stepniewska, K, Bassat, Q, Gonzalez, R, Baudin, E, Checchi, F, Espie, E, Grandesso, F, Nabasumba, C, Schramm, B, Björkman, A, Bompart, F, Lameyre, V, Bonnet, M, Borrmann, S, Bousema, T, Cenci, F, Cot, M, Faucher, J, Kapulu, M, Marsh, K, Mayxay, M, Newton, P, Roper, C, Deloron, P, Djimde, A, Fofana, B, Doumbo, O, Sagara, I, Dorsey, G, Rosenthal, P, Drakeley, C

“…The gametocytocidal properties of antimalarial drugs are important for malaria elimination efforts. …”

Genomic insights into Vibrio cholerae O1 responsible for cholera epidemics in Tanzania between 1993 and 2017 by Hounmanou, Yaovi Mahuton Gildas, Leekitcharoenphon, Pimlapas, Kudirkiene, Egle, Mdegela, Robinson H., Hendriksen, Rene S., Olsen, John Elmerdahl, Dalsgaard, Anders

“…The strains were less drug resistant with approximate 10-kb deletions found in the SXT element, which encodes resistance to sulfamethoxazole and trimethoprim. …”
Get full text

Synthesis and characterization of silver nanoprism-based nanostructures by Mohammad Mehdi Shahjamali

“…On the other hand, the hollow cavity makes the encapsulation of materials of interest possible which candidates it for drug delivery, photothermal cancer therapy and other bioapplications.…”
Get full text

Cryo-electron microscopy structure of the Mycobacterium tuberculosis cytochrome bcc:aa₃ supercomplex and a novel inhibitor targeting subunit cytochrome cI by Mathiyazakan, Vikneswaran, Wong, Chui Fann, Harikishore, Amaravadhi, Pethe, Kevin, Grüber, Gerhard

Get full text

Luteolin escape mutants of dengue virus map to prM and NS2B and reveal viral plasticity during maturation by Vasudevan, Subhash G., Peng, Minhua, Swarbrick, Crystall Marie Dawn, Chan, Kitti Wing-Ki, Luo, Dahai, Zhang, Wei, Lai, Xiaoping, Li, Geng

Get full text
Get full text

Waning of specific antibodies against Delta and Omicron variants five months after a third dose of BNT162b2 SARS-CoV-2 vaccine in elderly individuals by Goh, Yun Shan, Rouers, Angeline, Fong, Siew-Wai, Zhuo, Nicole Ziyi, Hor, Pei Xiang, Loh, Chiew Yee, Huang, Yuling, Neo, Vanessa Kexin, Kam, Isaac Kai Jie, Wang, Bei, Ngoh, Eve Zi Xian, Salleh, Siti Nazihah Mohd, Lee, Raphael Tze Chuen, Pada, Surinder, Sun, Louisa Jin, Ong, Desmond Luan Seng, Somani, Jyoti, Lee, Eng Sing, Maurer-Stroh, Sebastian, Wang, Cheng-I., Leo, Yee Sin, Ren, Ee Chee, Lye, David C., Young, Barnaby Edward, Ng, Lisa F. P., Renia, Laurent

Get full text

Navigating the real world: a grounded theory-based exploration of autistic adolescents identity formation in Marcelo in the real world by Yang, Shuo, Mani, Manimangai, Omar, Noritah

“…The use of grounded theory methodology enables a full examination of Marcelo's experiences and the fundamental mechanisms guiding the development of his identity. …”
Get full text

Three Provocations for Civic Crowdfunding by Davies, Rodrigo

“…This paper considers civic crowdfunding — the use of crowdfunding for projects that produce community or quasipublic assets — and argues that its emergence demands a fresh set of questions and approaches. The work draws on critical case studies constructed through fieldwork in the US, the UK and Brazil, and a discourse analysis of civic crowdfunding projects collected from platforms by the author. …”
Get full text

SP.236 / ES.SP236 Exploring Pharmacology, Spring 2009 by Gusman, Mariya, Fallows, Zak

“…From Abilify to Zyrtec, the world is full of interesting drugs. Such substances have cured diseases, started wars, and ended careers. …”
Get full text

Interventions for managing skeletal muscle spasticity following traumatic brain injury by Synnot, Anneliese, Chau, Marisa, Pitt, Veronica, O'Connor, Denise, Gruen, Russell Lindsay, Wasiak, Jason, Clavisi, Ornella, Pattuwage, Loyal, Phillips, Kate

“…The four studies without useable results were funded by pharmaceutical or medical technology companies. It was difficult to draw conclusions about the effectiveness of these interventions due to poor reporting, small study size and the fact that participants with TBI were usually only a proportion of the overall total. …”
Get full text
Get full text

Chitosan nanofibrous scaffold with graded and controlled release of ciprofloxacin and BMP-2 nanoparticles for the conception of bone regeneration by Zhang, Sihan, Zhao, Guanglei, Mahotra, Manish, Ma, Shiyuan, Li, Wenrui, Lee, Hiang Wee, Yu, Hong, Sampathkumar, Kaarunya, Xie, Denghui, Guo, Jinshan, Loo, Joachim Say Chye

Get full text

The effect of regularly dosed paracetamol versus no paracetamol on renal function in Plasmodium knowlesi malaria (PACKNOW) : study protocol for a randomised controlled trial by Cooper, Daniel J., Plewes, Katherine, Grigg, Matthew J., Rajahram, Giri S., Piera, Kim A., William, Timothy, Chatfield, Mark D., Yeo, Tsin Wen, Dondorp, Arjen M., Anstey, Nicholas M., Barber, Bridget E.

“…The inexpensive and widely available drug paracetamol inhibits CFHb-induced lipid peroxidation via reduction of ferryl haem to the less toxic Fe3+ state, and has been shown to reduce oxidative damage and improve renal function in patients with sepsis complicated by haemolysis as well as in falciparum malaria. …”
Get full text
Get full text

Pathogen diversity and antimicrobial resistance transmission of Salmonella enterica serovars Typhi and Paratyphi A in Bangladesh, Nepal, and Malawi: a genomic epidemiological study... by Dyson, ZA, Ashton, PM, Khanam, F, Chunga Chirambo, A, Shakya, M, Meiring, JE, Tonks, S, Karkey, A, Msefula, C, Clemens, JD, Dunstan, SJ, Baker, S, Dougan, G, Pitzer, VE, Basnyat, B, Qadri, F, Heyderman, RS, Gordon, MA, Holt, KE, Pollard, AJ, STRATAA Study Group

“…S Typhi genotype 4.3.1 (H58) was common in all sites, but with different dominant variants (4.3.1.1.EA1 in Blantyre, 4.3.1.1 in Dhaka, and 4.3.1.2 in Kathmandu). …”

‘On-demand’ soft tissue adhesives by Mogal, Vishal Tukaram

“…Various plasma parameters were investigated for controlling model drug release and soft-tissue adhesion of polyester thin films. …”
Get full text

Mitochondrial dysfunction in Down Syndrome: from pathology to therapy by Tan, Kai-Leng, Lee, Han-Chung, Cheah, Pike-See, Ling, King-Hwa

“…Mitochondrial dysfunctions have been described in Down syndrome (DS) caused by either partial or full trisomy of chromosome 21 (HSA21). Mitochondria play a crucial role in various vital functions in eukaryotic cells, especially in energy production, calcium homeostasis and programmed cell death. …”
Get full text

Metformin degradation with combined Ozone/UV/H2O2 process by Fujinami, Shoko Carissa

“…Metformin is a commonly used drug to treat Type 2 diabetic patients. As the number of diabetic patients globally has increased from 108 million in 1980 to 422 million in 2014, it can be seen that diabetes is a common form of illness and in Singapore, there is about 1 in 10 people suffering from diabetes (Lai, 2015). …”
Get full text

Efficacy and safety of tirzepatide for treatment of overweight or obesity. A systematic review and meta-analysis by Tan, Bryan, Pan, Xin-Hui, Chew, Jocelyn Han Shi, Goh, Rachel Sze Jen, Lin, Chaoxing, Anand, Vickram Vijay, Lee, Ethan Cheng Zhe, Chan, Kai En, Kong, Gwyneth, Ong, Christen En Ya, Chung, Charlotte Hui, Young, Dan Yock, Chan, Mark Y., Khoo, Chin Meng, Mehta, Anurag, Muthiah, Mark Dhinesh, Noureddin, Mazen, Ng, Cheng Han, Chew, Nicholas W. S., Chin, Yip Han

Get full text