The development and application of fish scale waste for tissue engineering applications : waste-to-resource conversion of resource resilient materials by Wang, Jun Kit

“…The SHCol was then chemically-modified and crosslinked to produce a water-soluble collagen with improved physicochemical properties as a potential drug carrier for biomedical applications. In addition, the chemically-modified SHCol (i.e. methylated SHCol) promoted growth of blood vessels (BVs) and lymphatic vessels (LVs) during in vivo studies. …”
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Understanding the viral protein structures of clinically relevant arboviruses and fragment-based screening for antivirals by Farhana Abu Bakar

“…In recent years, antiviral drug discovery has increasingly relied on the use of high-resolution structural information of important viral proteins and have led to the development of potent inhibitors. …”
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Sustained delivery of timolol maleate from liposomal nanocarriers by Ong, Leonard Chin Hui

“…Liposomes were prepared using thin film hydration and average particle size in the range of around 100 nm was prepared using a bench top extruder and drug was actively loaded by ammonium sulphate gradient loading technique. …”
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Streamoscope: A Low-Cost, Open-Source, USB-3-Capable Streaming Data Acquisition System for Low-Field MRI by Feld, Joseph W.

“…The Streamoscope can stream full-sample-rate raw MRI data into a computer to be processed in Python, enabling real time imaging. …”
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Effect of metabolite and temperature on artificial human sweat characteristics over a very wide frequency range (400 MHz–10.4 GHz) for wireless hydration diagnostic sensors by Lubangakene, Innocent, Virdee, Bal Singh, Jayanthi, Renu, Ganguly, Priyanka

“…As a result, analysis of electrolytes in this biofluid is gaining traction in the development of non-invasive sweat diagnostics to determine level of dehydration, cystic fibrosis and illicit drugs. This paper presents a wireless measurement modality of permittivity properties of sweat of different metabolite concentration levels exemplifying the full spectrum of human sweat. …”
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Design, simulation, and testing of a low cost laser micromachining system for flexible and rapid tissue-on-chip fabrication. by Nin, Jorge A.

“…This approach has the potential to overcome the limitations of traditional methods, enabling the next generation of sophisticated, physiologically relevant in vitro models for biomedical research and drug development. The successful development and validation of the FEM model, coupled with practical demonstrations, provide a solid foundation for further advancements in laser-based fabrication of tissue-on-chip devices, potentially accelerating drug discovery processes and enabling more accessible production of personalized medicine platforms.…”
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Optimising expression and purification of Dengue soluble E protein by Poh, Nina Yong Xin

“…It offers insights into viral-host immune interactions. The full-length E protein is essential for vaccine design. …”
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Colloidal quantum dot light-emitting diode architectures for high performance by Leck, Kheng Swee

“…In addition, in the thesis, we used gallium-doped zinc oxide (GZO) to replace tin-doped indium oxide (ITO) used as the electrode in QD-LEDs due to the increasingly expensive raw materials of ITO. The lowest sheet resistance and resistivity of the radio-frequency (RF) sputtered GZO films are 12.28 Ω/□ and 9.48×10-4 Ω·cm, respectively, comparable to those of commercial grade ITO. …”
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Layer-by-Layer Nanoparticles for Cytokine Delivery by Pires, Ivan S.

“…We also find that the LbL film conformation is key to maintaining therapeutic efficacy as thicker films hinder IL-12 delivery. …”
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Combined ultrasound and photoacoustic imaging of blood clot during microbubble-assisted sonothrombolysis by Das, Dhiman, Pramanik, Manojit

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The role of tumour necrosis factor alpha stimulated gene-6 on bone by Afrough, S

“…Depending on the severity of the disease, most patients are often treated with calcium/vitamin D and anti-resorptive drugs such as bisphosphonates or calcitonin. However, there are few options for bone formation using anabolic agents- such as Teriparatide (PTH_1-34), which have limited success, creating an unmet need for novel anabolic interventions.…”

Association of current Schistosoma mansoni, Schistosoma japonicum, and Schistosoma mekongi infection status and intensity with periportal fibrosis: a systematic review and meta-ana... by Ewuzie, A, Wilburn, L, Thakrar, DB, Cheng, H, Reitzug, F, Roberts, N, Malouf, R, Chami, GF

“…Two reviewers independently screened abstracts and full-text reports for eligibility. A third reviewer was consulted in cases of disagreement. …”

Improving access to pulmonary rehabilitation for patients with COPD treated for substance misuse in the London Borough of Islington by Narasimhan, Divya, Simpson, Jane, Stewart, Duncan

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Barriers and leverage points for seeing alcohol differently in integrated care systems in England: a senior stakeholder interview study by Madden, Mary, Stewart, Duncan, McCambridge, Jim

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A biodegradable ocular implant for long-term suppression of intraocular pressure by Ng, Xu Wen, Liu, Kerh Lin, Veluchamy, Amutha Barathi, Lwin, Nyein Chan, Wong, Tina T., Venkatraman, Subbu Subramanian

“…However, the topical mode of administration (eyedrops) is far from optimal because of the issues of low bioavailability, high drug wastage, and lack of patient compliance. Suboptimal control of the IOP leads to disease progression and eventually to blindness. …”
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Data for the ‘Orchid Observers’ project by Shuttleworth, S, O’Donnell, J, Lintott, C, Tweddle, J

“…Once the authors’ research papers have been published, a full, cleaned set of the analysed data will be deposited. …”

Investigation of Synthetic Proteins Produced via Automated Fast-Flow Peptide Synthesis by Cowfer, Amanda Elizabeth

“…In the research arena, luciferases have had broad applications for decades, including detection of environmental contaminants, diagnosis of pathogens, high-throughput screening for drug discovery, understanding protein-protein interactions, and more. …”
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Crosslinkable vegetable oil based natural materials for packaging applications by Ker, Adonica Yan Ting

“…In this project, the synthesis of castor oil and citric acid polyester was carried out to produce a biodegradable polymer film for packaging applications. Castor oil and citric acid been selected as raw materials due to its high versatility and potential in undergoing esterification reaction, leading to the formation of hydrolysable ester bonds, followed by the addition of resorcinol, 1,10 decandiol and 1,12 dodecandiol as a linker to adjust the polymer film mechanical and degradation properties.…”
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Immune Checkpoint Blockade sensitivity and Progression-Free Survival associates with baseline CD8+ T cell clone size and cytotoxicity by Watson, R, Tong, O, Taylor, C, Kumar Sharma, P, Verge De Los Aires, A, Mahe, E, Ruffieux, H, Nassiri, I, Middleton, M, Fairfax, B

“…The cells contained within the expression matrices and Seurat objects have undergone full pre-processing and QC steps and are used for the analysis and figures in the linked manuscript. …”

Duration of carbapenemase-producing enterobacteriaceae carriage in hospital patients by Mo, Yin, Hernandez-Koutoucheva, Anastasia, Musicha, Patrick, Bertrand, Denis, Lye, David C., Ng, Oon Tek, Fenlon, Shannon N., Chen, Swaine L., Ling, Moi Lin, Tang, Wen Ying, Barkham, Timothy, Nagarajan, Niranjan, Cooper, Ben S., Marimuthu, Kalisvar

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