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1
Controllable charge transfer via DNA molecules
Published 2015“…Although the comprehensive fundamental description of charge transfer along DNA is still missing, the process can be categorized into oxidative holes and reductive electrons transfer/transport. …”
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Thesis-Doctor of Philosophy -
2
Electrochemical DNA biosensor based on nanoporous alumina membrane
Published 2014“…In recent years, due to the high sensitivity and sequence specificity, as well as rapid detection, the electrochemical DNA biosensors are promising for genetic screening and detection of deoxyribonucleic acid. …”
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Thesis -
3
Characterization of ubiquitin-activated DNA-protein crosslink repair in vitro
Published 2024“…DPCs repair is critical for maintaining genome stability, however, the knowledge of the DPC repair pathways is still limited. SPRTN, a DNA-dependent metalloprotease, has been identified as the major protease in repairing DPCs. …”
Thesis -
4
Optimized code design for constrained DNA data storage with asymmetric errors
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Journal Article -
5
Multifunctional systems in synthetic biology: Single-stranded DNA signals controls precise gene activation
Published 2025“…Selective gene activation was achieved by using different promoters or by using inhibitors to remove undesired signals by the DNA strand displacement reaction. Moreover, DNA signals were divided in half to construct complex logic gates (AND-OR-AND-OR-AND gates) that controlled gene activation. …”
Thesis -
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Alternative splicing in the DBD linker region of p63 modulates binding to DNA and iASPP in vitro
Published 2025“…Moreover, the concomitant loss of the charged amino acids in the alternatively spliced version decreases the affinity of p63 to its cognate DNA element two- to threefold. mRNAs encoding full-length p63, as well as its alternatively spliced version, are present in all tissues that we investigated, albeit in differing ratios. …”
Journal article -
8
Mapping the structural and dynamical features of multiple p53 DNA binding domains : insights into loop 1 intrinsic dynamics
Published 2014“…The transcription factor p53 regulates cellular integrity in response to stress. p53 is mutated in more than half of cancerous cells, with a majority of the mutations localized to the DNA binding domain (DBD). …”
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Journal Article -
9
Enhancing early warning: A DNA biosensor with polyaniline/graphene nanocomposite for label-free voltammetric detection of saxitoxin-producing harmful algae
Published 2024“…Yearly reports of detrimental effects resulting from harmful algal blooms (HAB) are still received in Malaysia and other countries, particularly concerning fish mortality and seafood contamination, both of which bear consequences for the fisheries industry. …”
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Article -
10
iN6-methylat (5-step) : identifying DNA N⁶-methyladenine sites in rice genome using continuous bag of nucleobases via Chou's 5-step rule
Published 2021“…DNA N⁶-methyladenine is a non-canonical DNA modification that occurs in different eukaryotes at low levels and it has been identified as an extremely important function of life. …”
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Journal Article -
11
Molecular and biochemical characterisation of human casein kinase I alpha splice variants
Published 2009“…To date, only a human CKIas cDNA has been published (Tapia et al., 1994; Fish et al., 1995). …”
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Thesis -
12
Leveraging imperfect restoration for data availability attack
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Conference Paper -
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14
Whole genome sequencing of hepatitis B virus using tiled amplicon (HEPTILE) and probe based enrichment on Illumina and Nanopore platforms
Published 2025“…Hepatitis B virus (HBV) whole genome sequencing (WGS) is currently limited as the DNA viral loads (VL) of many clinical samples are below the threshold required to generate full genomes using current sequencing methods. …”
Journal article -
15
Studies of the Fanconi anemia pathway
Published 2016“…Upon the appearance of ICLs, the FANCD2/FANCI complex is monoubiquitinated, and localised to the sites of DNA lesion. While the molecular mechanism of how the FA pathway operates is emerging, there are still questions remaining, such as if there is a sensor for ICLs being able to activate the FA pathway, or the timing of the recruitment of the FANCD2/FANCI heterodimer to damaged chromatin. …”
Thesis -
16
Amplifying signals in the tumor microenvironment for drug development and diagnostics
Published 2024“…At the same time, improving the sensitivity of ctDNA-based tests, that remains limited by the scarcity of ctDNA in blood, holds the key to unlock the full potential of liquid biopsy across many important clinical applications. …”
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Thesis -
17
An experimental design of a robotic delivery company
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Final Year Project (FYP) -
18
Structural features that affect β2 integrin expression and regulation of adhesion
Published 2013“…To establish the correlation between LAD-1 genotype and phenotype, as well as better understand integrin function and structure, 19 LAD-1 missense mutants that recently identified were introduced into the pcDNA3 plasmid containing the ITGB2 cDNA. These plasmids were transfected into HEK293T cells together with that of either the αL, αM, αX subunits. …”
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Thesis -
19
Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of epithelial cancers
Published 2025“…While these inferred SNV and CNV states can be used to resolve clonal phylogenies, however, it is still unknown how faithfully transcript-based tumour phylogenies reconstruct ground truth DNA-based tumour phylogenies. …”
Journal article -
20
Complex Queries in a Shared Multi User Relational Cloud Database
Published 2017“…While DaaS is becoming more and more popular enterprises start considering it as an option to reduce IT maintenance costs. …”
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Conference Paper