On the composition of Sr₂Fe₁.₅Mo₀.₅O₆₋δ – Sm₀.₂Ce₀.₈O₂₋δ composite as fuel electrodes for hydrogen reversible solid oxide cells by Li, Hao-Yang, Kamlungsua, Kittiwat, Ng, Kelvin, Shin, Ji-Yoon, Su, Pei-Chen

“…Polarization resistance changes over the steam content show the parabolic trend with the optimal humidity at 20 vol% at open circuit voltage and in fuel cell mode, while in electrolyzer mode, highly humidified hydrogen is favored. …”
Get full text

Improved mobility and photovoltaic performance of two-dimensional Ruddlesden−Popper (ThMA)₂(MA)₂M₃I₁₀ perovskites applied in perovskite solar cells by Sun, Ping-Ping, Kripalani, Devesh Raju, Chi, Weijie

“…Two-dimensional Ruddlesden−Popper (2DRP) perovskites have received extensive attention for perovskite solar cells (PSCs) application due to their enhanced thermal and light stability, high photoluminescence quantum yield, and long carrier lifetime. …”
Get full text

Assessing nanotoxicity of food-relevant particles: a comparative analysis of cellular responses in cell monolayers versus 3D gut epithelial cultures by Gautam, Archana, Lim, Hui Kheng, Li, Jasmine Jia’En, Hughes, Christopher Owen, Yeo, Calvin Wee Sing, Rakshit, Moumita, Leavesley, David Ian, Lim, Michelle Jing Sin, Tan, Joseph Choon Wee, Tan, Li Yi, Chan, Joanne Sheot Harn, Smith, Benjamin Paul Chapman, Ng, Kee Woei

“…Hence, the current study aims to compare two cell models by examining the toxicological impacts of two food-relevant NPs (SiO2 and Ag) on intestinal epithelia using monolayer Caco-2 cells and full-thickness 3D tissue models of human small intestines (EpiIntestinalTM). …”
Get full text

Cell-free hemoglobin mediated oxidative stress is associated with acute kidney injury and renal replacement therapy in severe falciparum malaria: an observational study by Plewes, Katherine, Kingston, Hugh W.F., Ghose, Aniruddha, Maude, Richard J., Herdman, M. Trent, Leopold, Stije J., Ishioka, Haruhiko, Hasan, Md. Mahtab Uddin, Haider, Md. Shafiul, Alam, Shamsul, Piera, Kim A., Charunwatthana, Prakaykaew, Silamut, Kamolrat, Yeo, Tsin Wen, Faiz, Md. Abul, Lee, Sue J., Mukaka, Mavuto, Turner, Gareth D. H., Anstey, Nicholas M., Jackson Roberts II, L., White, Nicholas J., Day, Nicholas P. J., Hossain, Md. Amir, Dondorp, Arjen M.

“…Background: Intravascular hemolysis is an intrinsic feature of severe malaria pathophysiology but the pathogenic role of cell-free hemoglobin-mediated oxidative stress in severe malaria associated acute kidney injury (AKI) is unknown. …”
Get full text
Get full text

Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells by Kitajima, Shojiro, Lee, Kian Leong, Fujioka, Masaki, Sun, Wendi, You, Jia, Chia, Grace Sushin, Wanibuchi, Hideki, Tomita, Shuhei, Araki, Marito, Kato, Hiroyuki, Poellinger, Lorenz

“…Most strikingly, we identified the emergence of CD70-expressing cells derived from CD70-negative cell lines upon prolonged hypoxia exposure or DNMT1 inhibition, both of which significantly reduced CpG-nucleotide methylations within CD70 promoter region. …”
Get full text
Get full text

G-cleave LC3B biosensor: monitoring autophagy and assessing resveratrol's synergistic impact on doxorubicin-induced apoptosis in breast cancer cells by Liao, C, Long, Y, Tsai, M, Lin, C, Hsu, K, Lee, C

“…The specificity of G-cleave LC3B biosensor was confirmed via CRISPR gene editing of pivotal autophagy regulator ATG4B, yielding diminished luciferase activity in MDA-MB-231 breast cancer cells. Notably, the G-cleave LC3B biosensor exhibited strong concordance with established autophagy metrics, encompassing LC3B lipidation, SQSTM1 degradation, and puncta accumulation analysis. …”

In vitro anti-cancer and antimicrobial effects of manganese oxide nanoparticles synthesized using Glycyrrhiza uralensis leaves extract on breast cancer cell lines by Althobiti, Maryam Musleh, Alzahrani, Badr, Elderdery, Abozer Y., Alzerwi, Nasser A. N., Rayzah, Musaed, Elkhalifa,, Ahmed M. E., Idrees, Bandar, Bakhsh, Ebtisam, Alabdulsalam, Abdulrahim A., Mohamedain, A., Kumar, Suresh S., Mok, Pooi Ling

“…DAPI, EtBr/AO dual staining, and Annexin-V-FITC-based flow cytometry analysis revealed that PF127-coated Mn2O3 NP-treated breast cancer cells exhibit nuclear damage and apoptotic cell death, resulting in cell cycle arrest in the S phase. …”
Get full text

Induction of apoptosis and the signalling pathways involved by dillenia suffruticosa dichloromethane root extract in mcf-7 and mda-mb-231 breast cancer cells by Foo, Jhi Biau

“…Previous study reported that dichloromethane extract of D. suffruticosa root (DCM-DS) was the most cytotoxic towards breast cancer cells. The present study investigated the mode of cell death and the signalling pathways involved in MCF-7 and MDA-MB-231 breast cancer cells treated with DCM-DS. …”
Get full text

Nanoparticle self-assembled hollow TiO2 spheres with well matching visible light scattering for high performance dye-sensitized solar cells by Lu, Jinlin, Guo, Chun Xian, Pang, Hongchang, Yang, Hongbin, Li, Chang Ming

“…Submicrometer-sized hollow TiO2 spheres are directly self-assembled from TiO2 nanoparticles without using any template or surfactant as a scattering layer for dye-sensitized solar cells, showing good visible light scattering match to significantly improve the photoconversion efficiency.…”
Get full text
Get full text

Characterization of poly(vinylidenefluoride-co-hexafluoroprolylene) membranes containing nanoscopic AlO(OH)n filler with Li/LiFePO4 cell by Aravindan, Vanchiappan, Senthilkumar, V., Nithiananthi, P., Vickraman, P.

“…Finally, Li/polymer membrane/LiFePO4cell was fabricated, and cycling performance of the cell was evaluated at C/10 rate. …”
Get full text
Get full text

Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes by de Jesus, Daniel S., Mak, Tracy C. S., Wang, Yi-Fang, von Ohlen, Yorrick, Bai, Ying, Kane, Eva, Chabosseau, Pauline, Chahrour, Catherine M., Distaso, Walter, Salem, Victoria, Tomas, Alejandra, Stoffel, Markus, Rutter, Guy A., Latreille, Mathieu

“…Objective:b-cell dedifferentiation has been revealed as a pathological mechanism underlying pancreatic dysfunction in diabetes. …”
Get full text

Synthesis of TiO2 hollow nanofibers by co-axial electrospinning and its superior lithium storage capability in full-cell assembly with olivine phosphate by Zhang, Xiang, Aravindan, Vanchiappan, Kumar, Palaniswamy Suresh, Liu, Huihui, Jayaraman, Sundaramurthy, Ramakrishna, Seeram, Madhavi, Srinivasan

“…We report the formation and extraordinary Li-storage properties of TiO2 hollow nanofibers by co-axial electrospinning in both half-cell and full-cell configurations. Li-insertion properties are first evaluated as anode in half-cell configuration (Li/TiO2 hollow nanofibers) and found reversible insertion of ~0.45 moles are feasible at current density of 100 mA g–1. …”
Get full text
Get full text

Correlation between proton conductivity, thermal stability and structural symmetries in novel HPW-meso-silica nanocomposite membranes and their performance in direct methanol fuel cells by Zeng, Jie, Shen, Pei Kong, Lu, Shanfu, Xiang, Yan, Li, Lin, De Marco, Roland, Jiang, San Ping

“…The high proton conductivity and excellent performance of the new methanol fuel cells demonstrate the promise of HPW-meso-silica nanocomposites with 3D mesostructures as a new class of inorganic proton exchange membranes for use in direct methanol fuel cells (DMFCs).…”
Get full text
Get full text

Synergistic effect of 5-fluorouracil and the small molecule Wnt/β-catenin inhibitor iCRT3 on Caco-2 colorectal cancer cells in vitro by Smarslik, Maren, Inal, Jameel

“…Wnt/β-catenin signalling plays a crucial role in CRC carcinogenesis and resistance, as Wnt expression is upregulated in 5-FU-resistant cells, protecting them from cell cycle arrest and apoptosis, thereby contributing to drug resistance. …”
Get full text

A Coxsackievirus B1-mediated nonlytic extracellular vesicle-to-cell mechanism of virus transmission and its possible control through modulation of EV release by Jorfi, Samireh, Ansa-Addo, Ephraim A., Mariniello, Katia, Warde, Purva, Bin Senian, Ahmad Asyraf, Stratton, Dan, Bax, Bridget E., Levene, Michelle, Lange, Sigrun, Inal, Jameel

“…Like most non-enveloped viruses, CVB1 mainly uses cell lysis to spread. Details of a nonlytic virus transmission remain unclear. …”
Get full text

Effects of HSV-G47∆ oncolytic virus on telomerase and telomere length alterations in glioblastoma multiforme cancer stem cells under hypoxia and normoxia conditions by Vazifehmand, Reza, Saeed Ali, Dhuha, Monem Homaie, Foroozandeh, Molaei Jalalvand, Fatemeh, Othman, Zulkefley, Deming, Chau, Stanslas, Johnson, Sekawi, Zamberi

“…Background: Due to the existence of tumor stem cells with tumorigenicity properties and resistance patterns, treatment of glioblastoma is not easy. …”

Cytotoxicity assessment of α helix Antarctic yeast oriented antifreeze peptide (Afp1m) on M. dunni (Clone III8C) cells by Khan, Muhammad Shuaib, Abdul Rahman, Mohd Basyaruddin, Abu Bakar, Mohd Zuki, Noordin, Mohammed Mustapha, Ullah, Shakeeb, Abdul Abubakar, Adamu, Rehman, Saifur, Saddiqua, Aisha, Mohammad Yusof, Loqman

“…The cell viability was assessed using MTT Assay (Tetrazolium dye MTT 3-(4, 5 dimethylthiazol-2-yl)-2, 5-10 diphenyltetrazolium bromide) against the positive control cells (Clone III8C) thatshowed 86.73 ± 6.92 % viability of cells (103.9 ± 6.56 %, 104.3 ± 5.13%, 100.9 ± 1.71%, 102.8 ± 1.24%, and 100.00 ± 0.0%). …”
Get full text

Cu2ZnSn(S,Se)4 kesterite solar cell with 5.1% efficiency using spray pyrolysis of aqueous precursor solution followed by selenization by Zeng, Xin, Tai, Kong Fai, Zhang, Tianliang, Ho, Chun Wan John, Chen, Xiaodong, Huan, Alfred, Sum, Tze Chien, Wong, Lydia H.

“…Kesterite thin film solar cell has been fabricated by chemical spray pyrolysis (CSP) of an aqueous solution followed by high temperature selenization. …”
Get full text
Get full text

The combined activation of KCa3.1 and inhibition of Kv11.1/hERG1 currents contribute to overcome Cisplatin resistance in colorectal cancer cells by Pillozzi, Serena, D'Amico, Massimo, Bartoli, Gianluca, Gasparoli, Luca, Petroni, Giulia, Crociani, Olivia, Marzo, Tiziano, Guerriero, Angela, Messori, Luigi, Severi, Mirko, Udisti, Roberto, Wulff, Heike, Chandy, Kanianthara George, Becchetti, Andrea, Arcangeli, Annarosa

“…Results: Cisplatin-resistant CRC cells expressed higher levels of KCa3.1 and Kv11.1 channels, compared with Cisplatin-sensitive CRC cells. …”
Get full text

1,3,5-triazaspiro[5.5]undeca-2,4-dienes as selective Mycobacterium tuberculosis dihydrofolate reductase inhibitors with potent whole cell activity by Yang, Xuan, Wedajo, Wassihun, Yamada, Yoshiyuki, Dahlroth, Sue-Li, Neo, Jason Jun-Long, Dick, Thomas, Chui, Wai-Keung

“…This study provided compelling evidence that compound 20b and 20c exerted whole cell antimycobacterial activity through DHFR inhibition. …”
Get full text