PARP1 resolves DNA replication defects in PCNA-associated DNA repair disorder by Wang, L

Subjects: “…Cell biology…”

Know Thy Cell-Free DNA: Early Detection of Microsatellite Instability Using Ultra-Low-Pass Cell-Free DNA Sequences by Lu, Nicole

“…Microsatellites are inherently more mutable than other genomic locations, and since cancer cells undergo many more cell divisions, microsatellites are useful for distinguishing tumor DNA from normal (non-cancerous) DNA. …”
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Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT) by Kusuma, Frances Karla, Prabhu, Aishvaryaa, Tieo, Galen, Syed Moiz Ahmed, Dakle, Pushkar, Yong, Wai Khang, Pathak, Elina, Madan, Vikas, Jiang, Yan Yi, Tam, Wai Leong, Kappei, Dennis, Dröge, Peter, Koeffler, H. Phillip, Jeitany, Maya

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Overcoming immunosenescence: strategies to modulate DNA damage and senescence in immune cells and fibroblasts by Kell, L

Subjects:

DNA-Methylation Patterns in Trisomy 21 Using Cells from Monozygotic Twins by Sailani, M. Reza, Santoni, Federico A., Letourneau, Audrey, Borel, Christelle, Makrythanasis, Periklis, Hibaoui, Youssef, Popadin, Konstantin, Bonilla, Ximena, Guipponi, Michel, Gehrig, Corinne, Vannier, Anne, Carre-Pigeon, Frederique, Feki, Anis, Nizetic, Dean, Antonarakis, Stylianos E.

Subjects: “…Induced pluripotent stem cells…”
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Multimodal cell-free DNA whole-genome TAPS is sensitive and reveals specific cancer signals by Vavoulis, DV, Cutts, A, Thota, N, Brown, J, Sugar, R, Rueda, A, Ardalan, A, Howard, K, Matos Santo, F, Sannasiddappa, T, Miller, B, Ash, S, Liu, Y, Song, C, Nicholson, BD, Dreau, H, Tregidgo, C, Schuh, A

Alcaligenes sp. strain sum 123 in microbial fuel cells for bioelectricity generation and palm oil mill effluent (POME) treatment / by Athena Anak Dana, 1993-, author 618795

Exploring the induction of preproinsulin-specific Foxp3+ CD4+ Treg cells that inhibit CD8+ T cell-mediated autoimmune diabetes by DNA vaccination by Stifter, Katja, Schuster, Cornelia, Schlosser, Michael, Boehm, Bernhard Otto, Schirmbeck, Reinhold

“…DNA vaccination is a promising strategy to induce effector T cells but also regulatory Foxp3(+) CD25(+) CD4(+) Treg cells and inhibit autoimmune disorders such as type 1 diabetes. …”
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Platelets sequester extracellular DNA, capturing tumour-derived and free foetal DNA by Murphy, L

“…During cell death and aberrant mitosis, nucleated cells release chromosomal DNA, resulting in ‘cell free’ DNA in plasma (cfDNA). …”

Cytotoxicity and apoptotic DNA fragmentation evaluation of ethanolic extract of Phyllanthus niruri L. in Vero and primary feline testicular cells by Roslan, Rasydan Hadi, Choong, Siew Shean, Mohamed, Maizan, Abu Bakar, Md Zuki, Gilbert, Brenda Sabrina, Noralidin, Amalina, Izamin, Izzati, Mohd Sani, Nani Izreen

“…The MTT assay was performed to evaluate the cytotoxicity of these plant extracts on FTC and Vero cells. Apoptosis was assessed using DNA laddering assay on extracted DNA of the treated FTC cells and observed the DNA patterns in gel electrophoresis. …”
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Elucidating the effects of DNA modification on transcription by Yavorska, O

“…<p>DNA modifications play important roles in genome function of vertebrates. 5-methylcytosine (mC) has been extensively studied over the last 50 years as the most common covalent DNA modification, present at roughly 70% of CpGs in the human genome. …”

Incorporating a guanidine-modified cytosine base into triplex-forming PNAs for the recognition of a C-G pyrimidine–purine inversion site of an RNA duplex by Toh, Desiree-Faye Kaixin, Devi, Gitali, Patil, Kiran M., Qu, Qiuyu, Maraswami, Manikantha, Xiao, Yunyun, Loh, Teck Peng, Zhao, Yanli, Chen, Gang

“…PNAs incorporating multiple guanidine-modified cytosine residues are able to enter HeLa cells without any transfection agent.…”
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A human atlas of DNA methylation and hydroxymethylation by Inoue, M

“…Here, we present a novel human atlas of 5mC and 5hmC for major tissues, blood cell types, and common cancer types. Our atlas encompasses 116 samples from 13 healthy tissue types, 9 blood cell types, 10 tumour types, and 2 precancerous tissue types.…”

Controllable charge transfer via DNA molecules by Liu, Yuanjun

“…Although the comprehensive fundamental description of charge transfer along DNA is still missing, the process can be categorized into oxidative holes and reductive electrons transfer/transport. …”
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A versatile system for receptor-mediated gene delivery permits increased entry of DNA into target cells, enhanced delivery to the nucleus and elevated rates of transgene expression by Fisher, KD, Ulbrich, K, Subr, V, Ward, CM, Mautner, V, Blakey, D, Seymour, LW

“…Here we show that vascular endothelial growth factor (VEGF), transferrin and basic fibroblast growth factor (bFGF) can each be linked to polyHPMA-coated poly(L-lysine)/DNA complexes. All ligand-targeted complexes demonstrated increased uptake into receptor-positive cells (measured using plasmids containing 32P-dCTP), that could be antagonised with excess free ligand. …”

DNA-damage orchestrates self-renewal and differentiation via reciprocal p53 family and Hippo/Wnt/TGF-β pathway activation in embryonic stem cells by Ye, Y, Xie, W, Wang, X, Tan, S, Yang, L, Ma, Z, Zhu, Z, Chen, X, Liu, X, O’Neill, E, Chang, L, Zhang, W

“…DNA damage and repair mechanisms have been largely elucidated in mutated cancer cells or simple eukaryotes, making valid interpretations on early development difficult. …”

Alcaligenes sp. strain sum 123 in microbial fuel cells for bioelectricity generation and palm oil mill effluent (POME) treatment / by Athena Anak Dana, 1993-, author 618795, Nor Azimah Mohd. Zain, 1982-, supervisor 483537, Huszalina Hussin, 1977-, supervisor 620597, Fakulti Biosains dan Kejuruteraan Perubatan

Electrochemical DNA biosensor based on nanoporous alumina membrane by Deng, Jiajia

“…Presently, the approach to DNA membrane sensor is using two external Ag/AgCl electrodes or inert electrodes to measure ionic conductivity across the membrane in a two compartment cell. …”
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The role of circulating tumor DNA in melanomas of the uveal tract by Zameer, MZ, Jou, E, Middleton, M

“…Recently, advances in minimally-invasive liquid biopsy techniques and biomarkers such as circulating tumor DNA (ctDNA) have demonstrated potential to transform the field of cancer care by aiding diagnosis, prognosis and monitoring of various cancer types. …”

Characterization of ubiquitin-activated DNA-protein crosslink repair in vitro by Zhu, X

“…<p><strong><em>Introduction:</em></strong> DNA-Protein Crosslinks (DPCs) are a form of DNA damage caused by covalent attachment between proteins and DNA, which can lead to replication fork stalling, disruption of cell division, and ultimately cell death. …”