Controllable charge transfer via DNA molecules by Liu, Yuanjun

“…Although the comprehensive fundamental description of charge transfer along DNA is still missing, the process can be categorized into oxidative holes and reductive electrons transfer/transport. …”
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Electrochemical DNA biosensor based on nanoporous alumina membrane by Deng, Jiajia

“…In recent years, due to the high sensitivity and sequence specificity, as well as rapid detection, the electrochemical DNA biosensors are promising for genetic screening and detection of deoxyribonucleic acid. …”
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Characterization of ubiquitin-activated DNA-protein crosslink repair in vitro by Zhu, X

“…DPCs repair is critical for maintaining genome stability, however, the knowledge of the DPC repair pathways is still limited. SPRTN, a DNA-dependent metalloprotease, has been identified as the major protease in repairing DPCs. …”

Multifunctional systems in synthetic biology: Single-stranded DNA signals controls precise gene activation by Ng, SH

“…Selective gene activation was achieved by using different promoters or by using inhibitors to remove undesired signals by the DNA strand displacement reaction. Moreover, DNA signals were divided in half to construct complex logic gates (AND-OR-AND-OR-AND gates) that controlled gene activation. …”

Mapping the structural and dynamical features of multiple p53 DNA binding domains : insights into loop 1 intrinsic dynamics by Lukman, Suryani., Lane, David P., Verma, Chandra S.

“…The transcription factor p53 regulates cellular integrity in response to stress. p53 is mutated in more than half of cancerous cells, with a majority of the mutations localized to the DNA binding domain (DBD). …”
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Enhancing early warning: A DNA biosensor with polyaniline/graphene nanocomposite for label-free voltammetric detection of saxitoxin-producing harmful algae by Chwan Chuong Chin, Jeremy Jason, Akbar, Muhamad Afiq, Mohd Yusof, Nurul Yuziana, Pike, Andrew, Goh, Choo Ta, Mustapha, Shuhadah, Tan, Ling Ling

“…Yearly reports of detrimental effects resulting from harmful algal blooms (HAB) are still received in Malaysia and other countries, particularly concerning fish mortality and seafood contamination, both of which bear consequences for the fisheries industry. …”
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iN6-methylat (5-step) : identifying DNA N⁶-methyladenine sites in rice genome using continuous bag of nucleobases via Chou's 5-step rule by Le, Nguyen Quoc Khanh

“…DNA N⁶-methyladenine is a non-canonical DNA modification that occurs in different eukaryotes at low levels and it has been identified as an extremely important function of life. …”
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Molecular and biochemical characterisation of human casein kinase I alpha splice variants by Yong, Thomas Joon Kin.

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Leveraging imperfect restoration for data availability attack by Huang, Yi, Styborski, Jeremy, Lyu, Mingzhi, Wang, Fan, Kong, Adams Wai Kin

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Studies of the Fanconi anemia pathway by Liang, C

“…Upon the appearance of ICLs, the FANCD2/FANCI complex is monoubiquitinated, and localised to the sites of DNA lesion. While the molecular mechanism of how the FA pathway operates is emerging, there are still questions remaining, such as if there is a sensor for ICLs being able to activate the FA pathway, or the timing of the recruitment of the FANCD2/FANCI heterodimer to damaged chromatin. …”

An experimental design of a robotic delivery company by Foo, Melvin Maw Qing

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Structural features that affect β2 integrin expression and regulation of adhesion by Guan, Siyu

“…To establish the correlation between LAD-1 genotype and phenotype, as well as better understand integrin function and structure, 19 LAD-1 missense mutants that recently identified were introduced into the pcDNA3 plasmid containing the ITGB2 cDNA. These plasmids were transfected into HEK293T cells together with that of either the αL, αM, αX subunits. …”
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Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of epithelial cancers by Erickson, A, Figiel, S, Rajakumar, T, Rao, S, Yin, W, Doultsinos, D, Magnussen, A, Singh, R, Poulose, N, Bryant, RJ, Cussenot, O, Hamdy, FC, Woodcock, D, Mills, IG, Lamb, AD

“…While these inferred SNV and CNV states can be used to resolve clonal phylogenies, however, it is still unknown how faithfully transcript-based tumour phylogenies reconstruct ground truth DNA-based tumour phylogenies. …”

Complex Queries in a Shared Multi User Relational Cloud Database by Sidorov, Vasily, Ng, Wee Keong

“…While DaaS is becoming more and more popular enterprises start considering it as an option to reduce IT maintenance costs. …”
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A synthetic biology platform for malaria parasites based on orthogonal transcriptional control by Cárdenas Ramírez, Pablo

“…Malaria is responsible for half a million deaths each year in some of the poorest communities around the world. …”
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Unravelling 2-oxoglutarate turnover and substrate oxidation dynamics in 5-methylcytosine-oxidising TET enzymes by Šimelis, K, Belle, R, Kawamura, A

“…Here, we profile 5-methylcytosine (5mC)-oxidising Ten-Eleven Translocation (TET) enzymes using MS and 1H NMR spectroscopy methods and reveal a high degree of substrate oxidation-independent 2OG turnover under a range of conditions. 2OG decarboxylase activity is substantial (>20% 2OG turned over after 1 h) in the absence of substrate, while, under substrate-saturating conditions, half of total 2OG consumption is uncoupled from substrate oxidation. 2OG kinetics are affected by substrate and non-substrate DNA oligomers, and the sequence-agnostic effects are observed in amoeboflagellate Naegleria gruberi NgTet1 and human TET2. …”

Design and simulation of plasmonic metamaterials for sub-wavelength imaging in the visible range by Li, Dongdong

“…The resolution of conventional optical lens system is limited by diffraction to about half-wavelength of the incident light. Plasmonic metamaterials, which rely on surface plasmons (SPs) to confine and transmit the electromagnetic (EM) energy, provide a way to circumvent the diffraction-limit. …”
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Elucidating the genomic and transcriptomic profiles contributing to the overall survival of acute myeloid leukaemia patients with normal karyotype in Malaysia by Ambayya @ Ampiah, A Angeli

“…Acute myeloid leukaemia-normal karyotype (AML-NK) comprises almost half of the AML subtypes and exhibits heterogeneity in overall survival (OS). …”
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Conception of conjugative cloning vectors. by Tan, Peng Fei.

“…Further experimentation is still required to verify the sustainability and success of this triparental system.…”
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The study of radiotherapy resistance of hypoxic tumour for improving survival of cancer patient. by Goh, Yeek Teck.

“…Despite the advent of many new targeted cancer therapies, radiotherapy is still considered an important treatment modality in killing localised cancer cells. …”
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