Search alternatives:
hill » fill (Expand Search), hall (Expand Search)
call » all (Expand Search), cell (Expand Search)
kin » kind (Expand Search), skin (Expand Search)
dana, » data, (Expand Search), dan, (Expand Search), mana, (Expand Search)
hill » fill (Expand Search), hall (Expand Search)
call » all (Expand Search), cell (Expand Search)
kin » kind (Expand Search), skin (Expand Search)
dana, » data, (Expand Search), dan, (Expand Search), mana, (Expand Search)
-
1
Controllable charge transfer via DNA molecules
Published 2015“…Although the comprehensive fundamental description of charge transfer along DNA is still missing, the process can be categorized into oxidative holes and reductive electrons transfer/transport. …”
Get full text
Thesis-Doctor of Philosophy -
2
Electrochemical DNA biosensor based on nanoporous alumina membrane
Published 2014“…In recent years, due to the high sensitivity and sequence specificity, as well as rapid detection, the electrochemical DNA biosensors are promising for genetic screening and detection of deoxyribonucleic acid. …”
Get full text
Thesis -
3
Characterization of ubiquitin-activated DNA-protein crosslink repair in vitro
Published 2024“…DPCs repair is critical for maintaining genome stability, however, the knowledge of the DPC repair pathways is still limited. SPRTN, a DNA-dependent metalloprotease, has been identified as the major protease in repairing DPCs. …”
Thesis -
4
Web-server for discovering DNA motifs associated with genome instability
Published 2012Get full text
Final Year Project (FYP) -
5
The De Bruijn graph of non-sequential pattern repetitions in DNA strings
Published 2024“…In molecular biology, constructing a genome based on substantially many reads from multitudes of deoxyribonucleic acid (DNA) strings has become an insurmountable task; one which has been continuously addressed by the introduction of various assembly algorithms based on three steps called the overlap-layout-consensus strategy. …”
Get full text
Article -
6
New DNA motifs : structure and potential activity against HIV and cancer
Published 2012“…Guanine-rich oligonucleotides have the ability to adopt non-canonical structures, called G-quadruplexes. G-quadruplex structures are highly polymorphic, depending on their sequences and environmental conditions. …”
Get full text
Thesis -
7
Characterisation of Topoisomerase 1-cleavage complex repair
Published 2024“…<p>Topoisomerase 1 (TOP1) resolves DNA topological stress ahead of DNA replication and transcription. …”
Thesis -
8
Enhancing early warning: A DNA biosensor with polyaniline/graphene nanocomposite for label-free voltammetric detection of saxitoxin-producing harmful algae
Published 2024“…Yearly reports of detrimental effects resulting from harmful algal blooms (HAB) are still received in Malaysia and other countries, particularly concerning fish mortality and seafood contamination, both of which bear consequences for the fisheries industry. …”
Get full text
Article -
9
iN6-methylat (5-step) : identifying DNA N⁶-methyladenine sites in rice genome using continuous bag of nucleobases via Chou's 5-step rule
Published 2021“…DNA N⁶-methyladenine is a non-canonical DNA modification that occurs in different eukaryotes at low levels and it has been identified as an extremely important function of life. …”
Get full text
Journal Article -
10
-
11
Towards understanding genome regulation via high-resolution analysis of chromatin accessibility
Published 2023“…For both bulk and single-cell datasets, I show the robustness of EpiCall in peak calling down-sampled low-quality data, a significant advantage over current peak callers.…”
Thesis -
12
Studies of the Fanconi anemia pathway
Published 2016“…Upon the appearance of ICLs, the FANCD2/FANCI complex is monoubiquitinated, and localised to the sites of DNA lesion. While the molecular mechanism of how the FA pathway operates is emerging, there are still questions remaining, such as if there is a sensor for ICLs being able to activate the FA pathway, or the timing of the recruitment of the FANCD2/FANCI heterodimer to damaged chromatin. …”
Thesis -
13
Clonal phylogenies inferred from bulk, single cell, and spatial transcriptomic analysis of epithelial cancers
Published 2025“…While these inferred SNV and CNV states can be used to resolve clonal phylogenies, however, it is still unknown how faithfully transcript-based tumour phylogenies reconstruct ground truth DNA-based tumour phylogenies. …”
Journal article -
14
Hodge theory and its applications to molecular data analysis
Published 2022“…The complete DNA sequencing of the entire human genome, or better known as the Human Genome Project, concluded in 2003. …”
Get full text
Thesis-Doctor of Philosophy -
15
Structure and interaction of telomeric and telomerase RNA G-quadruplexes.
Published 2013“…The sugar-ring chemistry (deoxyribose vs. ribose) was found to affect the Kd of inter-molecular G-quadruplex (DNA-DNA vs. DNA-RNA vs. RNA-RNA intermolecular G-quadruplex). …”
Get full text
Thesis -
16
Conception of conjugative cloning vectors.
Published 2012“…Further experimentation is still required to verify the sustainability and success of this triparental system.…”
Get full text
Final Year Project (FYP) -
17
The study of radiotherapy resistance of hypoxic tumour for improving survival of cancer patient.
Published 2013“…Despite the advent of many new targeted cancer therapies, radiotherapy is still considered an important treatment modality in killing localised cancer cells. …”
Get full text
Final Year Project (FYP) -
18
Correlative light and electron microscopy of telomeric repeat-binding factor 1 in mammalian cells
Published 2019“…Telomeric chromatin consists of ‘TTAGGG’ DNA repeats sequences, nucleosomes and specific telomere-binding proteins called “shelterin”. …”
Get full text
Get full text
Thesis -
19
Protein profile in cells exposed to non-thermal radiofrequency-field
Published 2010“…The number of reports on the effects induced by radiofrequency (RF) electromagnetic fields radiation in various cellular systems is still increasing. Until now no satisfactory mechanism has been proposed to explain the biological effects of these RF fields. …”
Get full text
Final Year Project (FYP) -
20
Development and evaluation of clustering algorithms for microarray data analyses
Published 2008“…In this dissertation project, clustering algorithms have been implemented and applied to DNA microarray data analysis. An efficient and robust software system called GeneSpy has been eventually developed. …”
Get full text
Thesis