The role of PTEN in human bone marrow-derived mesenchymal stem cells mediated tumor cells suppression. by Toh, Xin Yi.

“…With the observed 26.2% of cell enhancement in MSC/ ∆Gli36-shPTEN co-culture, findings from the loss- of- function assay had indicated that expression of PTEN could be correlated with MSC-mediated suppression. …”
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Effects of hormonal regulation on cell number and cell size in determining fruit size: a mini-review by Siti Khadijah A. Karim, Zamri Zainal, Nik Marzuki Sidik

“…By providing a fundamental understanding of how fruit size is regulated in plants, the process of cell number production followed by the increase of cell size has been widely studied. …”
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Cytoophidium complexes resonate with cell fates by Li, Y, Liu, J

“…In 2010, we discovered that the metabolic enzyme CTP synthase (CTPS) can assemble a snake like structure inside cells, which we call the cytoophidium. Including CTPS, an increasing number of metabolic enzymes have been found to form cytoophidia in cells. …”

Regulation and function of innate-like T cells by Hagel, JP

“…It is expressed by NK- and T-cell subsets, particularly by innate-like T cells such as MAIT and γδT cells. …”

An epigenetic analysis of planarian stem cells by Dattani, A

“…Bivalent histone modifications in mammalian embryonic and germline stem cells enable transcriptional poising of genes, and consistent with this we find that bivalent genes in planarian NBs are marked by paused RNA Pol II at the promoter-proximal region. …”

Enhanced restoration of visual code after targeting ON bipolar cells compared to retinal ganglion cells with optogenetic therapy by Rogers, J, Hughes, S, Ebrahimi, A, Allen, A, Storchi, R, Lindner, M, Peirson, S, Badea, T, Hankins, M, Lucas, R

“…Optogenetic therapy is a promising vision restoration method where light-sensitive opsins are introduced to the surviving inner retina following photoreceptor degeneration. The cell type targeted for opsin expression will likely influence the quality of restored vision. …”

RNA interference silencing of interleukin-6 in mesenchymal stromal cells and antitumour efficacy against multiple myeloma cells by Teoh, Hoon Koon

“…In conclusion, both RNAi pathways were equally effective in suppressing IL-6 expression in MSC and displayed in vitro and in vivo antitumor efficacy against U266 cells. These findings support the feasibility of using RNAi as an alternative approach for targeted suppression of IL-6 in MSC to inhibit multiple myeloma cell growth.…”
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That's Not How We Do It Here! : A Story About How Organizations Rise, Fall - and Can Rise Again / by Kotter, John P., 1947-, author 368412, Rathgeber, Holger, author 507836

“…This book distills Kotter's decades of experi­ence and award-winning research to reveal why organizations rise and fall, and how they can rise again in the face of adversity"--…”

Inferring structural variant cancer cell fraction by Cmero, M, Yuan, K, Ong, CS, Schröder, J, PCAWG Evolution and Heterogeneity Working Group, Corcoran, NM, Papenfuss, T, Hovens, CM, Markowetz, F, Macintyre, G, PCAWG Consortium

“…We present SVclone, a computational method for inferring the cancer cell fraction of structural variant (SV) breakpoints from whole-genome sequencing data. …”

Determination of the life span of inflammatory dendritic cells by Tay, Yong Long

“…Dendritic cells (DCs) are highly efficient antigens presenting cells (APCs) which are responsible in processing and presenting antigens to naïve T-cells thereby activating the adaptive immune response. …”
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Cell-based assays in flowing and sessile drops by Prastowo, A

“…<p>Cell-based assays have been performed in aqueous drops within a bulk immiscible fluid phase, as an alternative to multi-titer plates. …”

Study of endothelial cell apoptosis using fluorescence resonance energy transfer (FRET) biosensor cell line with hemodynamic microfluidic chip system by Yu, J. Q., Liu, X. F., Chin, Lip Ket, Liu, Ai Qun, Luo, Kathy Qian

“…This finding may provide new insight into how glucose causes endothelial cell dysfunction, which is the major cause of diabetes-derived complications.…”
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Role of distinct dendritic cell subsets in disseminated candidiasis. by Teoh, Flora Poh Leng.

“…By finding immune cells that play a role in host defense against C. albicans, we may discover potential targets for vaccination and other immunotherapies. …”
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Investigation of charge transport in nanofiber based solar cells by Sabba Dharani

“…Dye sensitized solar cells (DSCs) have garnered a lot of attention owing to their ease of fabrication, low manufacturing costs and good device stability. …”
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Valley-layer coupling : a new design principle for valleytronics by Yu, Zhi-Ming, Guan, Shan, Sheng, Xian-Lei, Gao, Weibo, Yang, Shengyuan A.

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Establishment and optimization of induced pluripotent stem cell technologies by Amir Morshedi

“…This finding has had tremendous impact on drug discovery and disease modeling and there is great hope for these cells to replenish body cells for therapy. …”
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Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT) by Kusuma, Frances Karla, Prabhu, Aishvaryaa, Tieo, Galen, Syed Moiz Ahmed, Dakle, Pushkar, Yong, Wai Khang, Pathak, Elina, Madan, Vikas, Jiang, Yan Yi, Tam, Wai Leong, Kappei, Dennis, Dröge, Peter, Koeffler, H. Phillip, Jeitany, Maya

“…By performing anti-cancer compound library screen on isogenic cell lines and using extrachromosomal telomeric C-circles, as a bona fide marker of ALT activity, we identify a receptor tyrosine kinase inhibitor ponatinib that deregulates ALT mechanisms, induces telomeric dysfunction, reduced ALT-associated telomere synthesis, and targets, in vivo, ALT-positive cells. …”
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Experimental and simulation analysis of energy absorption capacity of 3D printed structure design by Low, Evans Tze Sheng

“…Future studies could explore the other different features or combinations that can be implemented together with a closed-cell foam model, farther optimizing and enhancing the energy absorption of the structure. …”
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Nanoparticle-induced chemoresistance: the emerging modulatory effects of engineered nanomaterials on human intestinal cancer cell redox metabolic adaptation by Wu, Zhuoran, Setyawati, Magdiel Inggrid, Lim, Hong Kit, Ng, Kee Woei, Tay, Chor Yong

“…Transcriptome profiling, bioinformatics analysis and siRNA gene knockdown experiments revealed the nuclear factor erythroid 2-related factor 2 (Nrf2) as the key modulator of the ZnO NP-induced drug resistance. Our findings suggest that a ROS-inducing ENM can emerge as a nano-stressor, capable of regulating the chemosensitivity of colon cancer cells.…”
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Cell charactetization in differnet regions of the native annulus fibrous in a porcine intervetebral disc model through cell sorting and molecular analysis by Teo, Tong

“…In this study, we will use cell sorting methods and carry out molecular analysis to find out more about the characteristics of the different regions of the native annulus fibrosus in the porcine intervertebral disc model.…”
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