Specific inhibition of PI3K p110δ inhibits CSF‐1‐induced macrophage spreading and invasive capacity by Mouchemore, KA, Sampaio, N, Murrey, MW, Stanley, ER, Lannutti, BJ, Pixley, FJ

“…While primary bone marrow‐derived macrophages and the immortalized bone marrow‐derived macrophage cell line M−/−.WT express all three class IA PI3K isoforms, p110δ predominates in the cell line. …”

Predicting rifampicin resistance in M. tuberculosis using machine learning informed by protein structural and chemical features by Lynch, C, Adlard, D, Fowler, P

“…</p> <br> <p><strong>Results:</strong> All four models behaved similarly with sensitivities and specificities in and 0.94-0.97 although we preferred the ensemble of Decision Tree models as inspect and understand. …”

Exploring proteins within the coccolith matrix by Dedman, CJ, Chauhan, N, González-Lanchas, A, Baldreki, C, Dowle, AA, Larson, TR, Lee, RBY, Rickaby, REM

“…Building consensus with existing work, we highlight the pentapeptide repeat as a feature which is associated with the coccolith matrix, being identified in all three examined species, and propose that this structural motif may play a role in controlling coccolith growth. …”

Structure and function of the smoothened extracellular domain in vertebrate hedgehog signaling by Rohatgi, Rajat, Nachtergaele, Sigrid, Whalen, Daniel M, Mydock, Laurel K, Zhao, Zhonghua, Malinauskas, Tomas, Krishnan, Kathiresan, Covey, Douglas F, Siebold, Christian, Ingham, Philip William

“…The oxysterol-binding groove in the Smo CRD is analogous to that used by Frizzled 8 to bind to the palmitoleyl group of Wnt ligands and to similar pockets used by other Frizzled-like CRDs to bind hydrophobic ligands. …”
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Separation of acetylene from carbon dioxide and ethylene by a water-stable microporous metal – organic framework with aligned imidazolium groups inside the channels by Lee, Jaechul, Chuah, Chong Yang, Kim, Jaheon, Kim, Youngsuk, Ko, Nakeun, Seo, Younggyu, Kim, Kimoon, Bae, Tae Hyun, Lee, Eunsung

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Surface modulation of hierarchical MoS2 nanosheets by Ni single atoms for enhanced electrocatalytic hydrogen evolution by Zhang, Huabin, Yu, Le, Chen, Tao, Zhou, Wei, Lou, David Xiong Wen

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Elucidating the effect of polyethylene terephthalate chain structure on its enzymatic degradation behavior by Lena, Jean-Baptiste, Gonçalves, Rui A., Kharel, Sharad, Kannan, Srinivasaraghavan, Verma, Chandra Shekhar, Pinchi, Keerthi Mohan, Lim, Sierin, Lam, Yeng Ming

“…Size, composition, randomness, thermal properties, and crystallinity of all polymers were determined. The polymers were then enzymatically degraded to compare the efficiency of PETase on different PET substrates. …”
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The LBP gene and its association with resistance to Aeromonas hydrophila in Tilapia by Xia, Jun Hong, Fu, Gui Hong, Liu, Feng, Yue, Gen Hua

“…In immune-related genes, the lipopolysaccharide-binding protein (LBP) gene is an important mediator of the inflammatory reaction. …”
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SU(3) topological insulators in the honeycomb lattice by Bornheimer, U., Miniatura, Christian, Grémaud, B.

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Digital keywords for China: perceptions and portrayals in English-language novels by Matthews, Graham, Cheung, Cally Hiu Tung

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The bHLH transcription factor OsPRI1 activates the Setaria viridis PEPC1 promoter in rice by Carvalho, P, Gomes, C, Gonçalves, I, Lourenço, TF, Vlad, D, Langdale, JA, Saibo, NJM

“…Cross-species comparisons showed that the SvPRI1 homolog binds to the <i>SvPEPC1</i> promoter but the maize ZmPRI1 does not bind to the <i>ZmPEPC1</i> promoter.…”

Synthesis, modification and application of fish skin gelatin-based hydrogel as sustainable and versatile bioresource of antidiabetic peptide by Munawaroh, Heli Siti Halimatul, Pratiwi, Riska Nur, Gumilar, Gun Gun, Aisyah, Siti, Rohilah, Siti, Nurjanah, Anisa, Ningrum, Andriati, Susanto, Eko, Pratiwi, Amelinda, Arindita, Ni Putu Yunika, Martha, Larasati, Chew, Kit Wayne, Show, Pau-Loke

“…Scanning electron microscope (SEM) observation showed that all hydrogels have a porous structure with irregular shapes and heterogeneous morphology. …”
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Experimental medicine study with stabilised native-like HIV-1 Env immunogens drives long-term antibody responses, but lacks neutralising breadth by Pollock, K, Cheeseman, H, McFarlane, L, Day, S, Tolazzi, M, Turner, H, Joypooranachandran, J, Shramko, K, Dispinseri, S, Mundsperger, P, Bontjer, I, Lemm, N-M, Coelho, S, Tanaka, M, Cole, T, Korber, B, Katinger, D, Ward, A, Scarlatti, G, Sanders, R, Sattentau, Q, Shattock, R

“…The seroconversion rate against Env was 100% with all participants having measurable anti-EnvIgG antibodies after their second injection and throughout the study. …”

Identification of potential critical virulent sites based on hemagglutinin of influenza A virus in past pandemic strains by Yin, Rui, Fransiskus, Xaverius Ivan, Zheng, Jie, Zhou, Xinrui, Chow, Vincent T. K., Kwoh, Chee Keong

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Achieving highly efficient electrocatalytic oxygen evolution with ultrathin 2D Fe-doped nickel thiophosphate nanosheets by Liang, Qinghua, Zhong, Lixiang, Du, Chengfeng, Luo, Yubo, Zheng, Yun, Li, Shuzhou, Yan, Qingyu

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Inorganic salt modified paper substrates utilized in paper based microfluidic sampling for potentiometric determination of heavy metals by Ding, Ruiyu, Krikstolaityte, Vida, Lisak, Grzegorz

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Bioresponsive microlasers with tunable lasing wavelength by Yuan, Zhiyi, Tan, Xiaotian, Gong, Xuerui, Gong, Chaoyang, Cheng, Xin, Feng, Shilun, Fan, Xudong, Chen, Yu-Cheng

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Skyrmion-driven topological Hall effect in a Shastry-Sutherland magnet by Swain, N., Shahzad, M., Paradezhenko, G. V., Pervishko, A. A., Yudin, D., Sengupta, Pinaki

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Subnanometric osmium clusters confined on palladium metallenes for enhanced hydrogen evolution and oxygen reduction catalysis by Prabhu, P., Do, Viet-Hung, Yoshida, Takefumi, Zhou, Yingtang, Ariga-Miwa, Hiroko, Kaneko, Takuma, Uruga, Tomoya, Iwasawa, Yasuhiro, Lee, Jong-Min

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Unravelling gene regulation in the epidermis during differentiation by Anisa Banu Abdul Rahim

“…Additionally, we found CPEB4, an RNA binding protein to be downstream of AMD1 and is a novel marker of keratinocyte differentiation. …”
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