Investigating viral glycosylation pathways for drug and vaccine development by Brun, J

“…Compounds of a global anti-COVID-19 effort called the “Moonshot project” targeting the main protease of SARS-CoV-2 were also screened and promising compounds were progressed further to produce a specific direct-acting SARS-CoV-2 antiviral compound. …”

YAP-DKK1 axis restricts regeneration to the isthmus of the human gastric glands by Zagami, C

“…</p> <p>The human stomach is organised into epithelial invaginations called gastric glands. While tissue damage can trigger regeneration at the gland base, in healthy conditions, stem cell activity is restricted to an anatomical niche called the isthmus. …”

Investigating cofactor transfer for a B₁₂-dependent enzyme by Duong, Alexander T.

“…MCM relies on two other proteins, a G-protein metallochaperone called methylmalonic aciduria type A protein (MMAA) and a protein called adenosyltransferase (ATR), to load and off-load cofactor. …”
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Co-translational integration of the light harvesting complex II and its associated pigments into polymeric membranes by Zapf, Thomas

“…Fluorescence measurements of purified proteopolymersomes indicate successful binding of pigments to the proteins within this new environment. …”
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Part I : Peptide functionalized materials for gram-negative bacteria targeted PDT and LPS sensing. Part II : Small peptide and membrane lipid based self-assembled nanostructures fo... by Liu, Fang

“…Generally, Gram-negative bacterial pathogens have additional outer membranes mainly composed of highly conserved and unique lipopolysaccharide (LPS) molecules, which serve as permeability barriers to prevent the cell bodies from toxic antimicrobial molecules1-2 including many photosensitizers, which have been successfully used in photoinactivation of Gram-positive strains.3-4 Furthermore, LPS, a potent inducer to human innate immune systems, hence called endotoxin, is now primarily responsible for sepsis associated with the infections of Gram-negative pethogens.5-6 Therefore, the most promising strategy is use of LPS neutralizing peptide as the binding ligand to deliver antibacterial agents meanwhile minimize the side effects.7 The first objective of the research in part I is the design and synthesis of photosensitizer-peptide conjugates for multivalent targeted cellular imaging and photodynamic inactivation (PDI) against Gram-negative bacterial strains. …”
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An epigenetic analysis of planarian stem cells by Dattani, A

“…<p>Planarian flatworms possess somatic pluripotent stem cells, called neoblasts (NBs), which are able to differentiate into all cell types that constitute the adult body plan. …”

The structure of hadrons and other potential phases of QCD by Schindler, Stella T.

“…Quantum chromodynamics (QCD) is a mathematical theory describing subatomic particles called quarks and gluons, and the strong force that binds them together into protons and neutrons. …”
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Characterisation of Topoisomerase 1-cleavage complex repair by Lascaux, P

“…As part of its enzymatic activity, TOP1 covalently binds to DNA, creating an intermediate known as TOP1 cleavage complex (TOP1cc) and a single strand DNA break which allows DNA to unwind. …”

Structure and interaction of telomeric and telomerase RNA G-quadruplexes. by Martadinata, Herry.

“…G-rich oligonucleotides are able to form four-stranded nucleic acid structures called G-quadruplexes in cationic solution. These structures are composed of multiple tetrad planes, in which each tetrad plane consists of four guanines that are Hoogsteen base-paired to one another. …”
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