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Effectiveness of interpretive exhibits in influencing students’ intention in birdwatching activity at a Bird Interpretive Center, Fraser’s Hill, Pahang, Malaysia
Published 2022“…Bird Interpretive Centre, Fraser’s Hill, operates to provide educational information on birds and birdwatching activity. …”
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22
Genome-wide mapping of Hif-1α binding sites in zebrafish
Published 2015“…As our approach uses embryos consisting of many cell types, it has the potential to uncover additional HIF regulated genes that have escaped detection in analogous mammalian cell culture studies. …”
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23
Quantifying conformational changes in the TCR:pMHC-I binding interface
Published 2024“…Thus, it remains an open question of whether movement occurs in the binding interface that enables the recognition and activation of T cells. …”
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A comparative analysis of ENCODE and Cistrome in the context of TF binding signal
Published 2024“…Two popular repositories for transcription factor binding sites data - ENCODE and Cistrome - process the same biological samples in alternative ways, and their results are not always consistent. …”
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25
The role of the reticulocyte-binding-like protein homologues of Plasmodium in erythrocyte sensing and invasion
Published 2013“…Two parasite protein families termed reticulocyte-binding-like protein homologues (RBL) and the erythrocyte-binding-like (EBL) protein family are conserved in all Plasmodium species and have been shown to play an important role in host cell recognition and invasion. …”
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YY1 binding is a gene-intrinsic barrier to Xist-mediated gene silencing
Published 2024Journal article -
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Quantum spin Hall effect and topological phase transition in InNxBiySb1−x−y/InSb quantum wells
Published 2017“…Quantum spin Hall (QSH) effect, a fundamentally new quantum state of matter and topological phase transitions are characteristics of a kind of electronic material, popularly referred to as topological insulators (TIs). …”
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28
Identification and application of self-binding zipper-like sequences in SARS-CoV spike protein
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29
Nontrivial quantum oscillation geometric phase shift in a trivial band
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Functional characterization of plasmodium falciparum reticulocyte binding like protein homologue 1 (PfRH1)
Published 2015“…One of the protein families involved in invasion, reticulocyte binding like protein homologues (PfRHs) has been suggested to be involved in host cell selection. …”
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Thesis -
32
Structural analysis of protein tyrosine phosphatase 1B reveals potentially druggable allosteric binding sites
Published 2020“…Catalytic proteins such as human protein tyrosine phosphatase 1B (PTP1B), with conserved and highly polar active sites, warrant the discovery of druggable nonactive sites, such as allosteric sites, and potentially, therapeutic small molecules that can bind to these sites. Catalyzing the dephosphorylation of numerous substrates, PTP1B is physiologically important in intracellular signal transduction pathways in diverse cell types and tissues. …”
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The role of ADAM10 and mucin-like molecules in modulating cell-cell interactions
Published 2023“…Uptake of apoptotic corpses by phagocytes is facilitated by the molecular expression and secretion of find-me and eat-me signals by apoptotic cells, balanced with negative efferocytic don’t eat-me sig- nals and don’t-come-close-to-me barriers. …”
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The novel quinoline derivative SKA-346 as a KCa3.1 channel selective activator
Published 2025“…The calcium-activated KCa3.1 channel plays a crucial role in T-cell immune response. Genetic manipulation of T-cells to upregulate the expression of K+ channels has been shown to boost T-cell cytotoxicity in cancer. …”
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Binding of TCR multimers and a TCR-like antibody with distinct fine-specificities is dependent on the surface density of HLA complexes
Published 2013“…Collectively, the results highlight the promiscuity of our soluble TCR, which could be an advantageous feature when targeting cells infected with a mutation-prone virus, but that binding of the soluble oligomeric TCR relies considerably on the surface density of the presented antigen.…”
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36
Multi-omics analysis and modelling of T cell immunity and interferon signalling pathways for engineered T cell therapy
Published 2022“…Cell type annotation methods are evaluated for their ability to identify closely-related T cell populations in single-cell RNA sequencing (scRNA-seq) data. …”
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Mapping the structural and dynamical features of multiple p53 DNA binding domains : insights into loop 1 intrinsic dynamics
Published 2014“…The transcription factor p53 regulates cellular integrity in response to stress. p53 is mutated in more than half of cancerous cells, with a majority of the mutations localized to the DNA binding domain (DBD). …”
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38
Cell-derived nanovesicles from mesenchymal stem cells as extracellular vesicle-mimetics in wound healing
Published 2023“…These findings suggest that MSC-CDNs could replace both whole cells and EVs in promoting wound healing and tissue regeneration.…”
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Stem cell genome-to-systems biology
Published 2013“…This allows for the determination of the molecular constituents that govern stem cell characteristics and conjointly with functional validations via genetic perturbation and protein location binding analysis necessitate the construction of the complex transcriptional regulatory network. …”
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Goblet cell differentiation in colorectal cancer
Published 2023“…Therefore, investigating the regulatory mechanisms associated with goblet cell differentiation is important for a better understanding of CRC and finding new approaches to its prevention and treatment.…”
Thesis