In vivo visualization of cells with fluorescent-labeled fab fragment. by Wee, Armanda Lixuan.

“…This includes the expensive and tedious process to generate fluorescent reporter mice, as well as the immunogenicity of fluorescent-labeled antibodies mediated by Fc receptor binding. Therefore in this study, we generated fluorescent-labeled Fab fragments and evaluated their use in cells for in vivo imaging. …”
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Study of endothelial cell apoptosis using fluorescence resonance energy transfer (FRET) biosensor cell line with hemodynamic microfluidic chip system by Yu, J. Q., Liu, X. F., Chin, Lip Ket, Liu, Ai Qun, Luo, Kathy Qian

“…This finding may provide new insight into how glucose causes endothelial cell dysfunction, which is the major cause of diabetes-derived complications.…”
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Role of distinct dendritic cell subsets in disseminated candidiasis. by Teoh, Flora Poh Leng.

“…By finding immune cells that play a role in host defense against C. albicans, we may discover potential targets for vaccination and other immunotherapies. …”
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Induction of z-conformation in ribosomal RNA by Z-DNA binding domain Zα of the human double-stranded RNA deaminase I (ADAR1) by Zhao, Jing

“…Recently our collaborators have discovered that ZαADAR1 binds stably to ribosomes inside E. coli and human cells leading to translational inhibition in vitro and in vivo (Feng, Li et al. 2011). …”
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Valley-layer coupling : a new design principle for valleytronics by Yu, Zhi-Ming, Guan, Shan, Sheng, Xian-Lei, Gao, Weibo, Yang, Shengyuan A.

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Establishment and optimization of induced pluripotent stem cell technologies by Amir Morshedi

“…This finding has had tremendous impact on drug discovery and disease modeling and there is great hope for these cells to replenish body cells for therapy. …”
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Signalling inhibition by ponatinib disrupts productive alternative lengthening of telomeres (ALT) by Kusuma, Frances Karla, Prabhu, Aishvaryaa, Tieo, Galen, Syed Moiz Ahmed, Dakle, Pushkar, Yong, Wai Khang, Pathak, Elina, Madan, Vikas, Jiang, Yan Yi, Tam, Wai Leong, Kappei, Dennis, Dröge, Peter, Koeffler, H. Phillip, Jeitany, Maya

“…By performing anti-cancer compound library screen on isogenic cell lines and using extrachromosomal telomeric C-circles, as a bona fide marker of ALT activity, we identify a receptor tyrosine kinase inhibitor ponatinib that deregulates ALT mechanisms, induces telomeric dysfunction, reduced ALT-associated telomere synthesis, and targets, in vivo, ALT-positive cells. …”
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Experimental and simulation analysis of energy absorption capacity of 3D printed structure design by Low, Evans Tze Sheng

“…Future studies could explore the other different features or combinations that can be implemented together with a closed-cell foam model, farther optimizing and enhancing the energy absorption of the structure. …”
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Nanoparticle-induced chemoresistance: the emerging modulatory effects of engineered nanomaterials on human intestinal cancer cell redox metabolic adaptation by Wu, Zhuoran, Setyawati, Magdiel Inggrid, Lim, Hong Kit, Ng, Kee Woei, Tay, Chor Yong

“…Transcriptome profiling, bioinformatics analysis and siRNA gene knockdown experiments revealed the nuclear factor erythroid 2-related factor 2 (Nrf2) as the key modulator of the ZnO NP-induced drug resistance. Our findings suggest that a ROS-inducing ENM can emerge as a nano-stressor, capable of regulating the chemosensitivity of colon cancer cells.…”
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Controlling the assembly of proteins and cells on SiO₂ surfaces by Seong, Jiehyun, 1973-

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Cell charactetization in differnet regions of the native annulus fibrous in a porcine intervetebral disc model through cell sorting and molecular analysis by Teo, Tong

“…In this study, we will use cell sorting methods and carry out molecular analysis to find out more about the characteristics of the different regions of the native annulus fibrosus in the porcine intervertebral disc model.…”
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BRCA1 regulation of breast cancer cell motility by Hernandez Nuñez, ZE

“…This thesis hypothesises the potential association between BRCA1 ubiquitin ligase activity and cell migration. Different databases were compiled to 1) identify substrates of BRCA1’s enzymatic activity, 2) find proteins that interact with BRCA1 and 3) find proteins with a role in regulating migration. …”

PCA based feature extraction for cell image retrieval by Ananthagunan Muthukumaran

“…The Eigenimage approach is a principal component analysis method, in which a small set of characteristic pictures are used to describe the variation between cell images. The goal is to find out the eigenvectors (eigenimage) of the covariance matrix of the distribution, spanned by a training sot of cell mages. …”
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Characterizing the Impact of Oligomerization on Redox Flow Cell Performance by Weiss, Trent A, Fan, Gang, Neyhouse, Bertrand J, Moore, Evan B, Furst, Ariel, Brushett, Fikile R

“…Post‐mortem analyses reveal that oligomerization does not meaningfully alter decay processes as evinced by similar capacity fade across all species. Broadly, these findings corroborate and extend upon previously developed relationships between molecular size, electrochemical properties, and flow cell performance.…”
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Vascular tissue engineering: investigation of endothelial cell function by Heng, Jolyn Xiuhui

“…In this study, defined polycaprolactone (PCL) nanofibers of different fiber diameters were treated with NaOH and adsorbed with gelatin to investigate cell attachment efficiency and growth rate. The findings revealed that gelatin adsorbed surfaces does not favour EC proliferation well and led to performing the next modification which is 1 M NaOH treatment for 4 h, 16 h, and 24 h for the PCL surfaces. 1 M NaOH treatment was first performed to improve the hydrophilicity of PCL. …”
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Understanding lived experiences of bereaved parents of children with chronic life-threatening Illness : towards a culture-specific and meaning-oriented narrative E-writing interven... by Dutta, Oindrila

“…Second, developed from the findings of the systematic review, a first-of-its kind qualitative research in the Asian context was subsequently conducted to elicit the lived experience of parents in Singapore whose children suffered and died from a chronic life-threatening illness. …”
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Elucidation of functional significance of plasmodium falciparum reticulocyte binding like protein homologues - RH1, RH2A AND RH4 during merozoite invasion. by Karthigayan Gunalan.

“…The successful invasion of Plasmodium falciparum depends on the recognition of host cell receptors by parasite ligands. One major family of ligands involved in these interactions is the Reticulocyte binding like protein Homologues (RHs). …”
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Conservation of red blood cell signalling in Plasmodium merozoite invasion by Yong, James Jia Ming

“…Red blood cells (RBC) possess essential signalling cascades that are involved in Plasmodium merozoite invasion. …”
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3D spheroid-microvasculature-on-a-chip for tumor-endothelium mechanobiology interplay by Zhang, Yingqi, Jiang, Fengtao, Zhao, Charles Yunduo, Cho, Ann-Na, Fang, Guocheng, Cox, Charles D., Zreiqat, Hala, Lu, Zu Fu, Lu, Hongxu, Ju, Arnold Lining

“…During the final stage of cancer metastasis, tumor cells embed themselves in distant capillary beds, from where they extravasate and establish secondary tumors. …”
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Growth and optimization of III-V semiconductor solar cell structures. by Lim, Kuo Hou.

“…In this thesis, MBE and micro fabrication processes are used to fabricate 1×1cm^2 single junction homoface GaAs thin film solar cells. Solar spectrum is used to explain and relate it with the material band gap. …”
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