Tips from an expert panel on the development of a clinical research protocol by Makram, AM, Elsheikh, R, Makram, OM, Van, NT, Nam, NH, Quan, NK, Duc, NTM, Nguye, NQT, Javes, GO, Elsheikh, SS, Imoto, A, Lee, P, Ohmagari, N, Aiga, H, Kamiya, Y, Endo, PT, Huy, NT

“…In this guide, we aim to provide detailed guidance with the key components and offer practical tips for crafting a research protocol in line with the various study designs. Specifically, the structure of a research protocol should contain the following items: (1) a title that is specific, catchy, and impressive within the word limitation; (2) an abstract that briefs the critical points of the study; (3) an introduction highlighting the study context from broad to narrow and defining the knowledge gap; (4) a justification underlining the significance of the proposed study; (5) Specific, Measurable, Attainable, Relevant, and Time-bound (SMART) objective(s) and aim(s); (6) a methodology covering seven sub-items, including [i] study design and settings, [ii] study subjects, [iii] sample size calculation and sampling, [iv] participants recruitment and follow-up, [v] questionnaire development, [vi] potential variables and outcomes, and [vii] data analysis plan; (7) dissemination of the results; (8) ethics and conflict of interests; (9) budgets analysis/ funding disclosure; and (10) references. …”

The four worlds of ‘welfare reality’ – social risks and outcomes in Europe by Ferragina, E, Seeleib-Kaiser, M, Spreckelsen, T

“…Outcomes cluster countries largely in line with previous institutionalist literature, differentiating between conservative, liberal, Mediterranean and social-democratic regimes. …”

Key Factors in Developing a Holistic Framework for Partnering in Sustainable Campus Development (S/O 13371) by Abdul Nifa, Faizatul Akmar, Salleh, Nurul Azita, Mohd Nawi, Mohd Nasrun

“…This rapid expansion of the education industry is also reflected by the increasing number of foreign universities launching local campuses in Malaysia. In line with the government's aim to place Malaysia as the top higher education provider in this region, it is imperative that campus development is at par with international universities especially in the matters of sustainability. …”
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Structural and mechanistic studies of herpes virus proteins by Patel, Vidhi Kanaiyalal

“…Herpes viruses are nuclear-replicating viruses, known to cause a variety of diseases in humans ranging from painful skin and genital lesions to life-threatening cancers. …”
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Chemical mediation of coral larval settlement by crustose coralline algae by Tebben, J., Motti, C. A, Siboni, Nachshon, Negri, A. P., Harder, T., Steinberg, Peter David, Hatta, Masayuki, Tapiolas, D. M., Schupp, P. J., Kitamura, Makoto

“…While the sources of such cues are well known, the links between their biological activity, chemical identity, presence and quantification in situ are largely missing. …”
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Deletion of VPS50 protein in mouse brain impairs synaptic function and behavior by Ahumada-Marchant, Constanza, Ancatén-Gonzalez, Carlos, Haensgen, Henny, Brauer, Bastian, Merino-Veliz, Nicolas, Droste, Rita, Arancibia, Felipe, Horvitz, H. Robert, Constantine-Paton, Martha, Arriagada, Gloria, Chávez, Andrés E., Bustos, Fernando J.

“…Patients with mutations in VPS50 show severe developmental delay and intellectual disability, characteristics that have been associated with autism spectrum disorders (ASDs). The mechanisms that link VPS50 mutations to ASD are unknown. …”
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Optimizing resource allocation in large communications satellite constellations by Pachler de la Osa, Nils

“…By testing existing designs, it is concluded that the number of satellites, as well as the link quality are the main drivers of performance. …”
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The Response Regulator OmpR Negatively Controls the Expression of Genes Implicated in Tilimycin and Tilivalline Cytotoxin Production in Klebsiella oxytoca by Varela-Nájera, Ramón G., De la Cruz, Miguel A., Soria-Bustos, Jorge, González-Horta, Carmen, Delgado-Gardea, Ma Carmen E., Yáñez-Santos, Jorge A., Cedillo, María L., Hirakawa, Hidetada, Fox, James G., Sánchez-Ramírez, Blanca, Ares, Miguel A.

“…Klebsiella oxytoca toxigenic strains represent a critical health threat, mainly due to their link to antibiotic-associated hemorrhagic colitis. …”
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TPPP acts downstream of RhoA-ROCK-LIMK2 to regulate astral microtubule organization and spindle orientation by Heng, Yi-Wen., Lim, Hong-Hwa., Mina, Theresia., Utomo, Prayudi., Zhong, Shaoping., Lim, Chwee-Teck., Koh, Cheng-Gee

“…Thus, our results reveal a new regulatory link between the actin cytoskeleton and the mitotic spindle during the early stages of mitosis.…”
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An efficient mechanism for dynamic multicast traffic grooming in overlay IP/MPLS over WDM networks by Cheng, Tee Hiang, Yu, Xiaojun, Xiao, Gaoxi

“…To facilitate request provisioning, OMP jointly utilizes a data learning (DL) scheme on the IP/MPLS layer for logical link cost estimation, and a lightpath fragmentation (LPF) based method on the WDM layer for improving resource sharing in grooming process. …”
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Annotated bacterial chromosomes from frame-shift-corrected long-read metagenomic data by Arumugam, Krithika, Bağcı, Caner, Bessarab, Irina, Beier, Sina, Buchfink, Benjamin, Górska, Anna, Qiu, Guanglei, Huson, Daniel H., Williams, Rohan B. H.

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NARD : whole-genome reference panel of 1779 Northeast Asians improves imputation accuracy of rare and low-frequency variants by Yoo, Seong-Keun, Kim, Chang-Uk, Kim, Hie Lim, Kim, Sungjae, Shin, Jong-Yeon, Kim, Namcheol, Yang, Joshua Sung Woo, Lo, Kwok-Wai, Cho, Belong, Matsuda, Fumihiko, Schuster, Stephan Christoph, Kim, Changhoon, Kim, Jong-Il, Seo, Jeong-Sun

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Controllability robustness against cascading failure for complex logistic network based on dynamic cascading failure model by Wang, Shaohua, Yang, Yue, Sun, Liyue, Li, Xiaoni, Li, Yongxing, Guo, Konghui

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Alteration of gate-oxide trap capture/emission time constants by channel hot-carrier effect in the metal-oxide-semiconductor field-effect transistor by Ju, Xin, Ang, Diing Shenp

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The potential of smartphone apps in informing protobacco and antitobacco messaging efforts among underserved communities : longitudinal observational study by Lee, Edmund Wei Jian, Bekalu, Mesfin Awoke, McCloud, Rachel, Vallone, Donna, Arya, Monisha, Osgood, Nathaniel, Li, Xiaoyan, Minsky, Sara, Viswanath, Kasisomayajula

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Visual attention guided pixel-wise just noticeable difference model by Zeng, Zhipeng, Zeng, Huanqiang, Chen, Jing, Zhu, Jianqing, Zhang, Yun, Ma, Kai-Kuang

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Highly transparent ITO/HfO2/ITO device for visible-light sensing by Kalaga, Pranav Sairam, Kumar, Dayanand, Ang, Diing Shenp, Tsakadze, Zviad

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Reconciling Bayesian and perimeter regularization for binary inversion by Dunbar, Oliver R. A., Dunlop, Matthew M., Elliott, Charles M., Hoang, Viet Ha, Stuart, Andrew M.

“…On the other hand, sparse or noisy data often demand a probabilistic approach to the reconstruction of images, to enable uncertainty quantification; the Bayesian approach to inversion, which itself introduces a form of regularization, is a natural framework in which to carry this out. In this paper the link between Bayesian inversion methods and perimeter regularization is explored. …”
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Prediction of readmission in geriatric patients from clinical notes: retrospective text mining study by Goh, Kim Huat, Wang, Le, Yeow, Adrian Yong Kwang, Ding, Yew Yoong, Au, Lydia Shu Yi, Poh, Hermione Mei Niang, Li, Ke, Yeow, Joannas Jie Lin, Tan, Gamaliel Yu Heng

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Metal-semiconductor-metal photodetectors on a GeSn-on-insulator platform for 2 m applications by Son, Bongkwon, Lin, Yiding, Lee, Kwang Hong, Margetis, Joe, Kohen, David, Tolle, John, Tan, Chuan Seng

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