Hypoxia-inducible factor-2 alpha up-regulates CD70 under hypoxia and enhances anchorage-independent growth and aggressiveness in cancer cells by Kitajima, Shojiro, Lee, Kian Leong, Fujioka, Masaki, Sun, Wendi, You, Jia, Chia, Grace Sushin, Wanibuchi, Hideki, Tomita, Shuhei, Araki, Marito, Kato, Hiroyuki, Poellinger, Lorenz

“…Most strikingly, we identified the emergence of CD70-expressing cells derived from CD70-negative cell lines upon prolonged hypoxia exposure or DNMT1 inhibition, both of which significantly reduced CpG-nucleotide methylations within CD70 promoter region. …”
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DevOps for Databases : A practical guide to applying DevOps best practices to data-persistent technologies / by Jambor, David, author 656261

“…Database administrators are no longer the only experts; site reliability engineers (SREs) and DevOps engineers are database experts as well. This blurring of the lines has led to increased responsibilities, making members of high-performing DevOps teams responsible for end-to-end ownership. …”
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Empowering Teen Mental Fitness : A Guide for Managing Anxiety, Depression, Stress, and Suicide / by Longe, Jacqueline L., editor 422209, Gale Group (Online service) 651863

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Empowering Teen Mental Fitness : A Guide for Managing ADHD/ADD, Bullying, PTSD, and Social Media / by Longe, Jacqueline L., editor 422209, Gale Group (Online service) 651863

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Sequence-Dependent & -Independent Effects of Intron-Mediated Enhancement (IME) by Kowal, Emma J. K.

“…In this study we report the design and execution of several massively parallel reporter assays (MPRAs), interrogating the effect of tens of thousands of synthetic and natural intron sequences on gene expression in the human HEK293T and HeLa cell lines. We observe that even with random internal sequence, most of these introns splice well and trigger IME. …”
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Multi-criteria re-entrant jobs scheduling problems using GA and AHP by Lin, Danping.

“…The validation is conducted in two experiments, firstly single GA is implemented for the re-entrant lines and later a new combination of GA and AHP is carried out. …”
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Barriers and leverage points for seeing alcohol differently in integrated care systems in England: a senior stakeholder interview study by Madden, Mary, Stewart, Duncan, McCambridge, Jim

“…Results: ICS formation occurred when services had been under sustained pressures with lines of communication and accountability emergent and unclear. …”
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The role of CD1a in dengue infection by Yang, J

“…To investigate the effect of dengue infection on the function of CD1a-reactive T cells, polyclonal blood T cells from patients and controls, and CD1a-autoreactive T cells clone/lines were utilised. The production of IFN-γ and GM-CSF by CD1a-autoreactive T cells was reduced when co-cultured with dengue-infected presenting cells. …”

Development of coherent detector technologies for sub-millimetre wave astronomy observations by Tan, B-K

“…</p> <p>Using the current 16-pixel 350 GHz SIS receiver, HARP-B, we have observed the ¹²CO J=3→2 emission lines from two nearby galaxies. An important result we found is that the ¹²CO J=3→2 correlates strongly with the 8 μm Polycyclic Aromatic Hydrocarbon emission.…”

Structure and inhibition of novel cyclin-dependent kinases by Dixon-Clarke, S

“…Preliminary trials using these relatively non-selective compounds to inhibit CDK16 in melanoma and medulloblastoma cancer cell lines revealed rebastinib as the more efficacious drug causing loss of cell proliferation in the 1-2 micromolar range. …”

Dwelling encounters: migration, diversity and ambivalence in an Istanbul neighborhood by Biehl, K

“…In this dissertation I apply a novel theoretical approach drawing on the concept of dwelling for understanding how residents of Kumkapı relate to their environment and make sense of it. I propose three lines of argument that unfold sequentially through the organizing structure of the thesis. …”

An aerodynamic investigation of a high-pressure turbine using rotor casing static pressure measurements at engine representative conditions with different tip designs, tip gaps, an... by Singh, D, Beard, PF, Cardwell, D, Staelens, V, Bahulekar, P, Stokes, M, Bather, S, Chana, K

“…Steady and unsteady casing static pressure measurements were acquired, using pneumatic lines and high-frequency response (∼100 kHz) Kulite pressure transducers, respectively. …”

Key transcriptional regulators of neutrophil function in inflammation by Ai, Z

“…</p> <p>To investigate the regulatory role of the selected TFs in neutrophils, I utilised HoxB8 myeloid progenitors as a model system for in vitro production of neutrophils and generated stable knockout lines for JUNB, RELB, IRF5, RFX2, KLF6, and RUNX1 in Hoxb8 myeloid progenitors, using the CRISPR/Cas9 mediated system. …”

BRCA1 regulation of breast cancer cell motility by Hernandez Nuñez, ZE

“…Time-lapse microscopy of breast cancer cell lines with various BRCA1 backgrounds was employed to evaluate the impact of inhibiting ubiquitin ligase activity. …”

How are cognitive maps formed and encoded in humans? by Glitz, L

“…In Chapter 4, we find evidence for the latter, with trajectory training resulting in neural encoding of the map that is more similar to separate transitive lines along rows and columns, the extent of which is related to behavioural accuracy. …”

Nanoparticles enhanced laser-induced breakdown spectroscopy for characterisation and discrimination of gemstones by Al-Juboori, Haider, Haider, Zhaib, Hang, Wei, Roslan, Sufi

“…Results have shown a significant enhancement in spectral features, i.e., the emergence of several new spectral lines of major gemstone elements in the UV-Vis regions of the NELIBS spectra, while the CLIBS spectra were devoid of any meaningful spectral information. …”
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Synthetic, spectroscopic, biological and X-ray crystallographic structural studies on a novel pyridine-nitrogen-bridged dimeric nickel(II) complex of a pentadentate N3S2 ligand by Akbar Ali, Mohammad, Mirza, Aminul Huq, Butcher, Ray J., Tarafder, M.T.H.

“…The anticancer properties of these compounds were also evaluated against Human T-lymphoblastic leukaemia cell lines. The Schiff base exhibits marked cytotoxicity against these cells, but its nickel(II) complex is inactive.…”
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Empowering Teen Mental Fitness : A Guide for Managing Addiction, Eating Disorders, OCD, and Trauma / by Longe, Jacqueline L. editor 422209, Gale Group (Online service) 651863

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Characterizing dry mass and volume changes in human multiple myeloma cells upon treatment with proteotoxic and genotoxic drugs by Liu, Xili, Moscvin, Maria, Oh, Seungeun, Chen, Tianzeng, Choi, Wonshik, Evans, Benjamin, Rowell, Sean M., Nadeem, Omar, Mo, Clifton C., Sperling, Adam S., Anderson, Kenneth C., Yaqoob, Zahid, Bianchi, Giada, Sung, Yongjin

“…We show that human MM cell lines (RPMI8226, MM.1S, KMS20, and AMO1) increase dry mass upon bortezomib treatment. …”
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A low-cost, open-source cylindrical Couette rheometer by Erni, Makita, Hart, A. John, Trumper, David, Owens, Crystal E.

“…As a result, rheometers are typically large, expensive, and require additional infrastructure (e.g., gas lines), rendering them inaccessible for regular use by many individuals, small organizations, and educators. …”
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