Dysregulation of the Pdx1/Ovol2/Zeb2 axis in dedifferentiated β-cells triggers the induction of genes associated with epithelial-mesenchymal transition in diabetes by de Jesus, Daniel S., Mak, Tracy C. S., Wang, Yi-Fang, von Ohlen, Yorrick, Bai, Ying, Kane, Eva, Chabosseau, Pauline, Chahrour, Catherine M., Distaso, Walter, Salem, Victoria, Tomas, Alejandra, Stoffel, Markus, Rutter, Guy A., Latreille, Mathieu

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Radiative corrections: from medium to high energy experiments by Afanasev, Andrei, Bernauer, Jan C., Blunden, Peter, Blümlein, Johannes, Cline, Ethan W., Friedrich, Jan M., Hagelstein, Franziska, Husek, Tomáš, Kohl, Michael, Myhrer, Fred, Paz, Gil, Schadmand, Susan, Schmidt, Axel, Sharkovska, Vladyslava, Signer, Adrian, Tomalak, Oleksandr, Tomasi-Gustafsson, Egle, Ulrich, Yannick, Vanderhaeghen, Marc

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Ligand-specific factors influencing GLP-1 receptor post-endocytic trafficking and degradation in pancreatic beta cells by Fang, Zijian, Chen, Shiqian, Manchanda, Yusman, Bitsi, Stavroula, Pickford, Philip, David, Alessia, Shchepinova, Maria M., Corrêa, Ivan R., Jr., Hodson, David J., Broichhagen, Johannes, Tate, Edward W., Reimann, Frank, Salem, Victoria, Rutter, Guy A., Tan, Tricia, Bloom, Stephen R., Tomas, Alejandra, Jones, Ben

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Device and material investigations of GaN enhancement-mode transistors for Venus and harsh environments by Xie, Qingyun, Niroula, John, Rajput, Nitul S., Yuan, Mengyang, Luo, Shisong, Fu, Kai, Isamotu, Mohamed Fadil, Palash, Rafid Hassan, Sikder, Bejoy, Eisner, Savannah R., Surdi, Harshad, Belanger, Aidan J., Darmawi-Iskandar, Patrick K., Aksamija, Zlatan, Nemanich, Robert J., Goodnick, Stephen M., Senesky, Debbie G., Hunter, Gary W., Chowdhury, Nadim, Zhao, Yuji, Palacios, Tomás

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Mitofusins Mfn1 and Mfn2 are required to preserve glucose- but not incretin-stimulated β-cell connectivity and insulin secretion by Georgiadou, Eleni, Muralidharan, Charanya, Martinez, Michelle, Chabosseau, Pauline, Akalestou, Elina, Tomas, Alejandra, Yong, Fiona Su Wern, Stylianides, Theodoros, Wretlind, Asger, Legido-Quigley, Cristina, Jones, Ben, Lopez-Noriega, Livia, Xu, Yanwen, Gu, Guoqiang, Alsabeeh, Nour, Cruciani-Guglielmacci, Céline, Magnan, Christophe, Ibberson, Mark, Leclerc, Isabelle, Ali, Yusuf, Soleimanpour, Scott A., Linnemann, Amelia K., Rodriguez, Tristan A., Rutter, Guy A.

“…Here, we generated mice with β-cell-selective, adult-restricted deletion knock-out (dKO) of the mitofusin genes Mfn1 and Mfn2 (βMfn1/2 dKO). βMfn1/2-dKO mice displayed elevated fed and fasted glycemia and a more than fivefold decrease in plasma insulin. …”
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16.412J / 6.834J Cognitive Robotics, Spring 2004 by Williams, Brian C., Roy, Nicholas

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ENIGMA CHEK2gether project: a comprehensive study identifies functionally impaired CHEK2 germline missense variants associated with increased breast cancer risk by Stolarova, Lenka, Kleiblova, Petra, Zemankova, Petra, Stastna, Barbora, Janatova, Marketa, Soukupova, Jana, Achatz, Maria Isabel, Ambrosone, Christine, Apostolou, Paraskevi, Arun, Banu K., Auer, Paul, Barnard, Mollie, Bertelsen, Birgitte, Blok, Marinus J., Boddicker, Nicholas, Brunet, Joan, Burnside, Elizabeth S., Calvello, Mariarosaria, Campbell, Ian, Chan, Sock Hoai, Chen, Fei, Chiang, Jian Bang, Coppa, Anna, Cortesi, Laura, Crujeiras-González, Ana, De Leeneer, Kim, De Putter, Robin, DePersia, Allison, Devereux, Lisa, Domchek, Susan, Efremidis, Anna, Engel, Christoph, Ernst, Corinna, Evans, D. Gareth R., Feliubadaló, Lidia, Fostira, Florentia, Fuentes-Ríos, Olivia, Gómez-García, Encarna B., González, Sara, Haiman, Christopher, Hansen, Thomas van Overeem, Hauke, Jan, Hodge, James, Hu, Chunling, Huang, Hongyan, Ishak, Nur Diana Binte, Iwasaki, Yusuke, Konstantopoulou, Irene, Kraft, Peter, Lacey, James, Lázaro, Conxi, Li, Na, Lim, Weng Khong, Lindstrom, Sara, Lori, Adriana, Martinez, Elana, Martins, Alexandra, Matsuda, Koichi, Matullo, Giuseppe, McInerny, Simone, Michailidou, Kyriaki, Montagna, Marco, Monteiro, Alvaro N. A., Mori, Luigi, Nathanson, Katherine, Neuhausen, Susan L., Nevanlinna, Heli, Olson, Janet E., Palmer, Julie, Pasini, Barbara, Patel, Alpa, Piane, Maria, Poppe, Bruce, Radice, Paolo, Renieri, Alessandra, Resta, Nicoletta, Richardson, Marcy E., Rosseel, Toon, Ruddy, Kathryn J., Santamariña, Marta, Dos Santos, Elizabeth Santana, Teras, Lauren, Toland, Amanda E., Trentham-Dietz, Amy, Vachon, Celine M., Volk, Alexander E., Weber-Lassalle, Nana, Weitzel, Jeffrey N., Wiesmuller, Lisa, Winham, Stacey, Yadav, Siddhartha, Yannoukakos, Drakoulis, Yao, Song, Zampiga, Valentina, Zethoven, Magnus, Zhang, Ze Wen, Zima, Tomas, Spurdle, Amanda B., Vega, Ana, Rossing, Maria, Del Valle, Jesús, De Nicolo, Arcangela, Hahnen, Eric, Claes, Kathleen B. M., Ngeow, Joanne, Momozawa, Yukihide, James, Paul A., Couch, Fergus J., Macurek, Libor, Kleibl, Zdenek

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The Islamic opposition in Malaysia : new trajectories and directions? by Ahmad Fauzi Abdul Hamid

“…The shattering defeat of PAS in the 2004 general elections, while holding on to the reins of government in the state of Kelantan by a tiny majority, heralded an era of introspection for party leaders and strategists. …”
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When Islamists play by the rules yet change the game by Chan, Wen Ling

“…The recent upgrading of the PAS Supporters Club to a legal entity, complete with party constitution amendments that recognize the new wing, not only makes the PAS promise of “PAS for all” selffulfilling, it provides the party an opportunity to lead the change away from race-based politicking.…”
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Diauxic lags explain unexpected coexistence in multi‐resource environments by Bloxham, Blox, Lee, Hyunseok, Gore, Jeff

“…We establish a tradeoff between Aci2’s fast growth and Pa’s short lags as their mechanism for coexistence. …”
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Homogeneous dose delivery for very high energy electron beams by Robertson, C

“…This solution required quadrupoles of modest strength and provided high transmission. The TOPAS Monte-Carlo code was used to investigate scattering foils as an alternative method for uniform beam production. …”

Malaysia’s opposition alliance at the crossroads : beginning of the end? by Yang Razali Kassim

“…The Malaysian Pakatan Rakyat opposition alliance is at a crossroads following the recent crisis over the Menteri Besar (Chief Minister) of Selangor: Whether the three partners, PKR, DAP, PAS, part ways or remain together depends on how the surprising turmoil within the Islamist party PAS is resolved…”
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Comparison of different molds (epoxy, polymer and silicon) for microfabrication by hot embossing technique by Gupta, A., Tang, P. S., Jena, Rajeeb Kumar, Yue, Chee Yoon, Lam, Yee Cheong

“…To allow such molds to be exploited fully, this study investigates the performance of silicon, epoxy and COC (TOPAS-6017 grade) molds to fabricate microchannels on COC (TOPAS-8007 grade) substrate using hot embossing. …”
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Une lecture du texte hébreu by Joosten, J

“…Il s’agit sans conteste d’un des morceaux les plus puissants que contient la Bible hébraïque, ce qui n’est pas peu dire. Mais l’impact, affectif et intellectuel, du récit ne conduit pas tous les lecteurs à la même interprétation. …”

Compact transformer based power combination techniques for millimeter-wave CMOS power amplifiers by Han, Jiangan

“…As an indispensable building block in RF-front-end, compact PAs are highly sought after especially for low cost and high volume production. …”
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Synthesis of the cyclo-tetrasilicates by Ng, Jing Jie.

“…Structural analysis was performed by collecting powder X-ray diffraction patterns, before using Topas 4.1 analysis to identify the various compounds formed through this solid-state chemical method. …”
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Predicting wealth score from remote sensing satellite images and household survey data using deep learning by Shekhar, Shashank, Singh, Pratibha, Mishra, Rashmi, Kumar, Sunil

“…The most exigent call of the United Nations’ 17 sustainable goals is to end poverty everywhere by 2030. Unlike in the past, when poverty was measured based on data collected through ground-level surveys, the new technology adopted by many developing and developed countries is to estimate the poverty index using remote sensing satellite images with the help of machine learning techniques. …”
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Structural basis for the ligand-dependent activation of heterodimeric AHR-ARNT complex by Diao, X, Shang, Q, Guo, M, Huang, Y, Zhang, M, Chen, X, Liang, Y, Sun, X, Zhou, F, Zhuang, J, Liu, S, Vogel, CFA, Rastinejad, F, Wu, D

“…Crystal structures of the AHR-ARNT-DNA complexes, bound with each of six established AHR ligands, including Tapinarof, 6-formylindolo[3,2-b]carbazole (FICZ), benzo[a]pyrene (BaP), β-naphthoflavone (BNF), Indigo and Indirubin, reveal an unconventional mode of subunit assembly with intimate association between the PAS-B domains of AHR and ARNT. AHR’s PAS-B domain utilizes eight conserved residues whose dynamic rearrangements account for the ability to bind to ligands through hydrophobic and π-π interactions. …”

Manufacturing AA6061 micro-molds by hot embossing for production of polymeric microfluidic devices by Tran, Nhat Khoa

“…Using the processing methodology developed, AA6061 micro-molds were successfully fabricated and the effectiveness of these molds was examined by hot embossing on TOPAS 8007 substrates. Finally, Anand’s large deformation theory for isotropic plastic solids has been demonstrated to be adequate in predicting the forming process of AA6061 in micro hot embossing.…”
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Modelling and analysis of lubricated piston skirt-cylinder sub-systems in internal combustion engines by Amirun Rasyid Abu Bakar

“…Dynamic viscosities of 0.01Pas – 0.04Pas was considered as they overlapped with the engine oils available are tested. …”
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