SP.236 / ES.SP236 Exploring Pharmacology, Spring 2009 by Gusman, Mariya, Fallows, Zak

“…From Abilify to Zyrtec, the world is full of interesting drugs. Such substances have cured diseases, started wars, and ended careers. …”
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Revealing the biotoxicity of phosphorene oxide nanosheets based on the villin headpiece by Zhang, Wei, Gou, Yuanyuan, Cheng, Li, Dong, Kaiwei, Sheng, Yijie, Ye, Chao, Yang, Xianqing, Mu, Yuguang

“…Phosphorene, a novel member of the two-dimensional nanomaterial family, has demonstrated great potential in biomedical applications, such as photothermal therapy, drug delivery and antibacterial. However, phosphorene is unstable and easily oxidized in an aerobic environment. …”
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Mitochondrial dysfunction in Down Syndrome: from pathology to therapy by Tan, Kai-Leng, Lee, Han-Chung, Cheah, Pike-See, Ling, King-Hwa

“…Mitochondrial dysfunctions have been described in Down syndrome (DS) caused by either partial or full trisomy of chromosome 21 (HSA21). Mitochondria play a crucial role in various vital functions in eukaryotic cells, especially in energy production, calcium homeostasis and programmed cell death. …”
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US exceptionalism? International trends in midlife mortality by Dowd, JB, Doniec, K, Zhang, L, Tilstra, A

“…<p><strong>Background:&nbsp;</strong>Rising midlife mortality in the USA has raised concerns, particularly the increase in &lsquo;deaths of despair&rsquo; (due to drugs, alcohol and suicide). Life expectancy is also stalling in other countries such as the UK, but how trends in midlife mortality are evolving outside the USA is less understood. …”

Vypal2: a versatile peptide ligase for precision tailoring of proteins by Zhang, Dingpeng, Wang, Zhen, Hu, Side, Lescar, Julien, Tam, James P., Liu, Chuan-Fa

“…Together, these examples firmly establish Asx-specific ligases, such as VyPAL2, as the biocatalysts of the future for site-specific protein modification, with a myriad of applications in basic research and drug discovery.…”
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Effect of metabolite and temperature on artificial human sweat characteristics over a very wide frequency range (400 MHz–10.4 GHz) for wireless hydration diagnostic sensors by Lubangakene, Innocent, Virdee, Bal Singh, Jayanthi, Renu, Ganguly, Priyanka

“…As a result, analysis of electrolytes in this biofluid is gaining traction in the development of non-invasive sweat diagnostics to determine level of dehydration, cystic fibrosis and illicit drugs. This paper presents a wireless measurement modality of permittivity properties of sweat of different metabolite concentration levels exemplifying the full spectrum of human sweat. …”
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Ordered hybrid nanoneedle arrays for gas sensing by Liu, Hai

“…This thesis presents ordered hybrid nanoneedle arrays for gas sensing application. The ion milling process on the metal/silicon material system is investigated in depth, in order to fabricate iron/silicon and platinum nanocrystallites/silicon hybrid nanoneedle array. …”
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Methods for the Study of Galactofuranose in Mycobacteria by Taylor, Katherine I.

“…However, it is conspicuously absent from human cells, thus establishing its biosynthetic pathways as important potential drug targets. Our knowledge about the biological roles of galactofuranose in cells is hampered by a dearth of methods by which to study it. …”
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Stock prediction using support vector regression by Manasa, Abburu.

“…The results were compared to results generated using BP and an inference was drawn as to why SVM-R is a better performing alternative to financial market data prediction as compared to BP. …”
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Combined ultrasound and photoacoustic imaging of blood clot during microbubble-assisted sonothrombolysis by Das, Dhiman, Pramanik, Manojit

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The role of tumour necrosis factor alpha stimulated gene-6 on bone by Afrough, S

“…Depending on the severity of the disease, most patients are often treated with calcium/vitamin D and anti-resorptive drugs such as bisphosphonates or calcitonin. However, there are few options for bone formation using anabolic agents- such as Teriparatide (PTH_1-34), which have limited success, creating an unmet need for novel anabolic interventions.…”

Amino-functionalised β-diketiminate ligands (N-nacnacs): Synthesis and coordination chemistry with Main Group elements by Huan, D

“…Comparison between the novel N-nacnac complexes and their classical β-diketiminate "Nacnac" analogues are drawn wherever possible, in order to highlight the differences in molecular properties brought about by the introduction of the σ-electron withdrawing/π-electron donating NMe₂ functions at the ligand backbone.…”

Duration of carbapenemase-producing enterobacteriaceae carriage in hospital patients by Mo, Yin, Hernandez-Koutoucheva, Anastasia, Musicha, Patrick, Bertrand, Denis, Lye, David C., Ng, Oon Tek, Fenlon, Shannon N., Chen, Swaine L., Ling, Moi Lin, Tang, Wen Ying, Barkham, Timothy, Nagarajan, Niranjan, Cooper, Ben S., Marimuthu, Kalisvar

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Effectiveness of cognitive behavior therapy and Reiki therapy on adolescents with depressive disorders inTehran, Iran by Charkhandeh, Mansoureh

“…Epidemiological studies from the literature on mental health of youth indicate that depression, drug abuse and suicide are among the three most common causes of death among young people. …”
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