The binding interface of kindlin-2 and ILK involves Asp344/Asp352/Thr356 in kindlin-2 and Arg243/Arg334 in ILK by Tan, Hui-Foon, Guan, Si-Yu, Chng, Choon-Peng, Ong, Li-Teng, Tan, Suet-Mien, Law, Alex Sai Kit

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Induction of z-conformation in ribosomal RNA by Z-DNA binding domain Zα of the human double-stranded RNA deaminase I (ADAR1) by Zhao, Jing

“…In order to provide theoretical foundations for the analysis of NMR spectral responses of ZαADAR1 to ribosomes we attempted to extend the conventional NMR relaxation theory to include a semi solid-state treatment of nuclear spin dynamics in large complexes. The main challenge to the classical NMR theory arises when one of the binding partners is so large that in the chemical shift time scale of solution NMR (milliseconds) it can be considered as practically static or solid-state-like. …”
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Sequence- and structure-specific probing of RNAs by short nucleobase-modified dsRNA-binding PNAs incorporating a fluorescent light-up uracil analog by Krishna, Manchugondanahalli Shivakumar, Toh, Desiree-Faye Kaixin, Meng, Zhenyu, Ong, Alan Ann Lerk, Wang, Zhenzhang, Lu, Yunpeng, Xia, Kelin, Prabakaran, Mookkan, Chen, Gang

“…The strategy of directly targeting double-stranded RNA (dsRNA) by triplex-formation is relatively underexplored mainly due to the weak binding at physiological conditions for the traditional triplex-forming oligonucleotides (TFOs). …”
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Design and Construction of Artificial Extracellular Matrix (aECM) Proteins from Escherichia coli for Skin Tissue Engineering by Low, Pearlie Si Jia, Tjin, Monica Suryana, Fong, Eileen

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Synthesis and development of novel small molecule inhibitors of nucleophilic hydrolases by Gayatri

Subnanometric osmium clusters confined on palladium metallenes for enhanced hydrogen evolution and oxygen reduction catalysis by Prabhu, P., Do, Viet-Hung, Yoshida, Takefumi, Zhou, Yingtang, Ariga-Miwa, Hiroko, Kaneko, Takuma, Uruga, Tomoya, Iwasawa, Yasuhiro, Lee, Jong-Min

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Label-free microfluidic cell sorting and detection for rapid blood analysis by Lu, Nan, Tay, Hui Min, Petchakup, Chayakorn, He, Linwei, Gong, Lingyan, Maw, Kay Khine, Leong, Sheng Yuan, Lok, Wan Wei, Ong, Hong Boon, Guo, Ruya, Li, Holden King Ho, Hou, Han Wei

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Seroprevalence of SARS-CoV-2 in children and adolescents by Ratcliffe, H

“…</p> <br> <p>The findings of ‘STORY’ confirm that SARS-CoV-2 infections in children are generally asymptomatic or mild and rarely progress to severe disease and hospitalisation. …”

Enzymatic preparation of diacylglycerols: lipase screening, immobilization, characterization and glycerolysis performance by Xie, Rui, Peng, Xianwu, Lee, Yee-Ying, Xie, Pengkai, Tan, Chin-Ping, Wang, Yong, Zhang, Zhen

“…Backgrounds: Glycerolysis, with its advantages of readily available raw materials, simple operation, and mild reaction conditions, is a primary method for producing diacylglycerol (DAG). …”

Structural study of plant cellulose synthase and atypical profilin3 by Qiao, Zhu

“…A low-resolution model of oligomeric full-length cellulose synthase was also obtained by Cryo-EM. …”
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Part I Targeting RNA duplexes with modified triplex-forming oligonucleotides Part II Allostery within a Watson-Crick RNA duplex and its application in studying RNA recognition by R... by Zhou, Yuan

“…Binding of full-length RIG-I and a triplex-forming oligonucleotide (TFO) also induces 2AP fluorescence enhancement. …”
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Anisotropic protein diffusion on nanosurface by Liu, Yang, Song, Xiaohan, Yang, Yanmei, Li, Yong-Qiang, Zhao, Mingwen, Mu, Yuguang, Li, Weifeng

“…Moreover, the mild binding strength between α-PC and HP35 does not cause distortion in the protein structure. …”
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Interaction Analyses of the Integrin β2 Cytoplasmic Tail with the F3 FERM Domain of Talin and 14-3-3ζ Reveal a Ternary Complex with Phosphorylated Tail by Chatterjee, Deepak, Lu, Lewis Zhiping, Tan, Suet-Mien, Bhattacharjya, Surajit

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Glycosylated copper sulfide nanocrystals for targeted photokilling of bacteria in the near‐infrared II window by Hou, Shuai, Mahadevegowda, Surendra Hittanahalli, Mai, Van Cuong, Chan‐Park, Mary Bee Eng, Duan, Hongwei

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Structural analysis of the novel influenza A (H7N9) viral Neuraminidase interactions with current approved neuraminidase inhibitors Oseltamivir, Zanamivir, and Peramivir in the pre... by Tran-To Su, Chinh, Ouyang, Xuchang, Zheng, Jie, Kwoh, Chee Keong

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Incorporating a guanidine-modified cytosine base into triplex-forming PNAs for the recognition of a C-G pyrimidine–purine inversion site of an RNA duplex by Toh, Desiree-Faye Kaixin, Devi, Gitali, Patil, Kiran M., Qu, Qiuyu, Maraswami, Manikantha, Xiao, Yunyun, Loh, Teck Peng, Zhao, Yanli, Chen, Gang

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N-methyl-D-aspartate receptor- antibody encephalitis impairs maintenance of attention to items in working memory by Dor, A, Harrison, C, Irani, SR, Al-Diwani, A, Grogan, J, Manohar, S

“…Additionally, patients reported the wrong item (misbinding errors) more than controls after congruent cues (Group x Delay [congruent condition], main effect of group, p=&lt;0.001). Our results suggest NMDARs are critical for both maintaining attention and feature binding.…”

Bifunctional diazirine reagent for covalent dyeing of Kevlar and inert polymer materials by Liu, Richard Y., Luo, Shao-Xiong Lennon, Hirst, Elizabeth S., Doona, Christopher J., Swager, Timothy M.

“…The reagent's structure features a trifluoromethyl diazirine group as a precursor to a carbene that binds the textile surface. On the reagent's other terminus, a benzyl bromide group acts as a site accessible for substitution reactions. …”
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Identification of novel functional compounds from forest onion and its biological activities against breast cancer by Nurkolis, Fahrul, Kurniatanty, Isma, Wiyarta, Elvan, Permatasari, Happy Kurnia, Mayulu, Nelly, Taslim, Nurpudji Astuti, Tjandrawinata, Raymond Rubianto, Hardinsyah, Hardinsyah, Tallei, Trina Ekawati, Tsopmo, Apollinaire, Radu, Son, Hadinata, Edwin, Kim, Bonglee, Ribeiro, Rosy Iara Maciel Azambuja, Syahputra, Rony Abdi

“…A natural resource with potential activity against breast cancer is forest onion, Eleutherine bulbosa (Mill.) Urb., but the identity of its active constituents and their mechanisms of action remain unexplored. …”
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Identification of RNA-Tis11b complexes in activated B cells. by Tang, Ngang Heok.

“…RNA-binding proteins (RBPs) play important roles in regulating gene expression at post-transcriptional level. …”
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