Biotin-streptavidin binding interactions of dielectric filled silicon bulk acoustic resonators for smart label-free biochemical sensor applications by Heidari, Amir, Yoon, Yong-Jin, Park, Woo-Tae, Su, Pei-Chen, Miao, Jianmin, Park, Mi Kyoung, Lin, Julius Tsai Ming

“…Sensor performance of a dielectric filled silicon bulk acoustic resonator type label-free biosensor is verified with biotin-streptavidin binding interactions as a model system. …”
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Biocementation of sand filled geotextile tubes by Yong, Hoi Zett

“…Nonetheless, the strength and durability of geotextile tubes that filled with sand or clay slurry still need to be improved. …”
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Mapping the structural and dynamical features of multiple p53 DNA binding domains : insights into loop 1 intrinsic dynamics by Lukman, Suryani., Lane, David P., Verma, Chandra S.

“…Loop 1 occupies two major conformational states: extended and recessed; the former but not the latter displays correlations in atomic fluctuations with those of loop 2 (~24 Å apart). Since loop 1 binds to the major groove whereas loop 2 binds to the minor groove of DNA, our results begin to provide some insight into the possible mechanism underpinning the cooperative nature of DBD binding to DNA. …”
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Molecular insights into evolution, mutations and receptor-binding specificity of influenza A and B viruses from outpatients and hospitalized patients in Singapore by Ivan, Fransiskus Xaverius, Zhou, Xinrui, Lau, Suk Hiang, Rashid, Shamima, Teo, Jasmine S. M., Lee, Hong Kai, Koay, Evelyn S., Chan, Kwai Peng, Leo, Yee Sin, Chen, Mark I. Cheng, Kwoh, Chee Keong, Chow, Vincent T.

“…Background: This study compared the genomes of influenza viruses that caused mild infections among outpatients and severe infections among hospitalized patients in Singapore, and characterized their molecular evolution and receptor-binding specificity. …”
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Employment value proposition in the social sector, Singapore by Ho, Rachel Hunling, Liang, Yun Tzu, Gan, Gek Sing

“…The widespread challenge of limited financial and human resources as well as ill-informed public are tremendous hindrances of social sector’s ability to do more.…”
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Bond order resolved 3d 5/2 and valence band chemical shifts of Ag surfaces and nanoclusters by Sun, Changqing, Qin, Wei, Wang, Yan, Huang, Yongli, Zhou, Zhaofeng, Yang, Chao

“…Incorporating the tight-binding theory and the bond order–length–strength (BOLS) correlation into the X-ray photoelectron spectra of Ag(111) and (100) surfaces and the Auger electron spectra of Ag nanoparticles deposited on Al2O3 and CeO2 substrates has led to quantitative information of the 3d5/2 and the valence binding energies of an isolated Ag atom and their shifts upon bulk, defect, surface, and nanocrystal formation. …”
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Enzymatic preparation of diacylglycerols: lipase screening, immobilization, characterization and glycerolysis performance by Xie, Rui, Peng, Xianwu, Lee, Yee-Ying, Xie, Pengkai, Tan, Chin-Ping, Wang, Yong, Zhang, Zhen

“…Backgrounds: Glycerolysis, with its advantages of readily available raw materials, simple operation, and mild reaction conditions, is a primary method for producing diacylglycerol (DAG). …”

Anisotropic protein diffusion on nanosurface by Liu, Yang, Song, Xiaohan, Yang, Yanmei, Li, Yong-Qiang, Zhao, Mingwen, Mu, Yuguang, Li, Weifeng

“…On the MBP surface, HP35 migrates mainly along the zigzag direction but can also easily stride over the ridges and grooves along the armchair direction. Moreover, the mild binding strength between α-PC and HP35 does not cause distortion in the protein structure. …”
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Bifunctional diazirine reagent for covalent dyeing of Kevlar and inert polymer materials by Liu, Richard Y., Luo, Shao-Xiong Lennon, Hirst, Elizabeth S., Doona, Christopher J., Swager, Timothy M.

“…The reagent's structure features a trifluoromethyl diazirine group as a precursor to a carbene that binds the textile surface. On the reagent's other terminus, a benzyl bromide group acts as a site accessible for substitution reactions. …”
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Identification of novel functional compounds from forest onion and its biological activities against breast cancer by Nurkolis, Fahrul, Kurniatanty, Isma, Wiyarta, Elvan, Permatasari, Happy Kurnia, Mayulu, Nelly, Taslim, Nurpudji Astuti, Tjandrawinata, Raymond Rubianto, Hardinsyah, Hardinsyah, Tallei, Trina Ekawati, Tsopmo, Apollinaire, Radu, Son, Hadinata, Edwin, Kim, Bonglee, Ribeiro, Rosy Iara Maciel Azambuja, Syahputra, Rony Abdi

“…A natural resource with potential activity against breast cancer is forest onion, Eleutherine bulbosa (Mill.) Urb., but the identity of its active constituents and their mechanisms of action remain unexplored. …”
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Elucidating the mechanism of mRNA transport using novel imaging technologies by Stoychev, D

“…The MS2-MCP system is used to insert into mRNAs of interest special structures to which RNA-binding proteins, fused to a fluorescent protein such as GFP, can then bind. …”

Methods for the Study of Galactofuranose in Mycobacteria by Taylor, Katherine I.

“…Finally, we characterized the kinetics of a mild electrophile, the squaric ester, and assessed its utility in selectively binding and modifying a key galactofuranosyl transferase involved in mycobacterial cell wall biosynthesis. …”
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Vypal2: a versatile peptide ligase for precision tailoring of proteins by Zhang, Dingpeng, Wang, Zhen, Hu, Side, Lescar, Julien, Tam, James P., Liu, Chuan-Fa

“…The last two decades have seen an increasing demand for new protein-modification methods from the biotech industry and biomedical research communities. Owing to their mild aqueous reaction conditions, enzymatic methods based on the use of peptide ligases are particularly desirable. …”
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Seroprevalence of SARS-CoV-2 in children and adolescents by Ratcliffe, H

“…</p> <br> <p>The findings of ‘STORY’ confirm that SARS-CoV-2 infections in children are generally asymptomatic or mild and rarely progress to severe disease and hospitalisation. …”

Methyl and dimethyl o-xylenyl-substituted fullerene acceptors for polymer solar cells by Kim, Hee Un, Park, Jong Baek, Grimsdale, Andrew Clive, Hwang, Do-Hoon

“…These values correlate with the binding affinities of the fluorophore and quencher. …”
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Using an ER-specific optogenetic mechanostimulator to understand the mechanosensitivity of the endoplasmic reticulum by Song, Yutong, Zhao, Zhihao, Xu, Linyu, Huang, Peiyuan, Gao, Jiayang, Li, Jingxuan, Wang, Xuejie, Zhou, Yiren, Wang, Jinhui, Zhao, Wenting, Wang, Likun, Zheng, Chaogu, Gao, Bo, Jiang, Liwen, Liu, Kai, Guo, Yusong, Yao, Xiaoqiang, Duan, Liting

“…Sustained mechanostimuli increase the levels of binding-immunoglobulin protein (BiP) expression and phosphorylated eIF2α, two markers for ER stress. …”
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Crack healing in reactive MgO-slag system via bacteria induced carbonate precipitation by Zheng, Yanying

“…In the Concrete industry, the most widely used binding ingredient for concrete, portland cement (PC), is accountable for around 8% of global anthropogenic carbon dioxide (CO2) emissions. …”
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Conformational changes involved in signal transduction in avian cryptochromes by Gehrckens, AS

“…</p> <p>Finally, by mapping conformational changes found in molecular dynamics simulations onto changes observed in a previous HDX-MS data set on the <em>Drosophila</em> cryptochrome, a few gaps left by the incomplete coverage of the current experimental data were filled by acquiring information on the phosphate-binding loop and the protrusion motif, two regions which have also been found to undergo light-induced structural changes for the avian cryptochromes investigated. …”

High-density lipoprotein function is modulated by the SARS-CoV-2 spike protein in a lipid-type dependent manner by Correa, Yubexi, Del Giudice, Rita, Waldie, Sarah, Thépaut, Michel, Micciula, Samantha, Gerelli, Yuri, Moulin, Martine, Delaunay, Clara, Fieschi, Franck, Pichler, Harald, Haertlein, Michael, Forsyth, V. Trevor, Le Brun, Anton, Moir, Michael, Russell, Robert A., Darwish, Tamim, Brinck, Jonas, Wodaje, Tigist, Jansen, Martin, Martín, César, Roosen-Runge, Felix, Cárdenas, Marité

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Three-component Friedel-Crafts-type difunctionalization of ynamides with (hetero)arenes and iodine(iii) electrophile by Kikuchi, Jun, Nagata, Toya, Ito, Shingo, Yoshikai, Naohiko

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