The molecular determinants of Polycomb-mediated gene repression by Fursova, N

“…In conclusion, through systematic dissection of the Polycomb system, I have provided compelling evidence for a variant PRC1-dependent logic for formation of Polycomb chromatin domains and repression of Polycomb target genes. Together, my findings place PRC1 and its catalytic activity at the forefront of Polycomb-mediated transcriptional silencing, paving the way for a mechanistic understanding of Polycomb system function.…”

Repurposing nitroxoline to address antibiotic resistance in the production of poultry for consumption by Zhou, Y

“…</p> <p>My studies and thesis underscore the potential of NTX as a viable alternative for bacterial infection prevention/treatment in poultry farming. The findings contribute to the development and prudent use of NTX in farm animal production, offering a promising solution to the challenge of AMR in agriculture.…”

Evaluating the impact, implementation experience and political economy of primary care networks in Kenya: protocol for a mixed methods study by Amboko, B, Nzinga, J, Tsofa, B, Mugo, P, Musiega, A, Maritim, B, Wong, E, Mazzilli, C, Ng’ang’a, W, Hagedorn, B, Turner, G, Musuva, A, Murira, F, Ravishankar, N, Hussein, S, Barasa, E

“…The two strands will be mixed during data collection to refine questions, with findings triangulated during analysis and interpretation to provide a comprehensive understanding of PCN implementation. …”

Childlessness and its associated factors among Chinese women: a nationwide population-based study by Han, Q, Dang, J, Wu, Y, Ye, W

“…Conclusions: This study used the most recent nationwide survey data from China to identify factors associated with childlessness and reproductive anxiety, with an emphasis on socio-economic factors and domestic violence. The findings highlight the significant impact of domestic violence on fertility behaviors and reproductive anxiety, providing valuable evidence for future policy interventions.…”

A systematic analysis of the contribution of genetics to multimorbidity and comparisons with primary care data by Murrin, O, Mounier, N, Voller, B, Tata, L, Gallego-Moll, C, Roso-Llorach, A, Carrasco-Ribelles, LA, Fox, C, Allan, LM, Woodward, RM, Liang, X, Valderas, JM, Khalid, S, Dudbridge, F, Lamb, SE, Mancini, M, Farmer, L, Boddy, K, Bowden, J, Melzer, D, Frayling, TM, Masoli, JAH, Pilling, LC, Violán, C, Delgado, J

“…We classified pairs of conditions as across or within-domain based on the international classification of disease.</p> <p><strong>Findings: </strong>We identified 72 chronic conditions, with 43.6% of 2546 pairs showing higher co-occurrence than chance in primary care and evidence of shared genetics. …”

Managing risks to the media from emerging networked technologies by Shere, ARK

“…</p> <p>This research includes the findings from an exploratory study to scope the novelty of focusing on journalists as a specific population threatened by the IoT. …”

Programs to Address Violence for Military Families: a Systematic Review by Dodge, J, Wortham, W, Kale, C, Williamson, V, Ross, A, Maher, S, Kononowech, J, Winters, J, Sullivan, K

“…Conclusion: This study had three main findings: (1) The majority of interventions were for Veterans and/or their partners rather than active service personnel; (2) All interventions reported positive outcomes in the reduction of self-reported IPV, with the majority of these outcomes maintained over time; (3) While we intended to assess military family-level interventions that targeted IPV and CM, we only found three studies that targeted or included CM. …”

Inhibiting IP6K1 confers atheroprotection by elevating circulating apolipoprotein A-I by Liu, X, Zhang, Z, Aguirre, T, Shipton, ML, Fu, L, Du, J, Furkert, D, Qi, J, Chin, AC, Riley, AM, Liu, T, Zhang, X, Potter, BVL, Fiedler, D, Zhu, Y, Fu, C

“…</p> <p><strong>Conclusions:&nbsp;</strong>Our findings reveal a mechanism by which blocking IP6K1 boosts apoA-I production. …”

Acute seizure risk in patients with encephalitis: development and validation of clinical prediction models from two independent prospective multicentre cohorts by Wood, GK, Babar, R, Ellul, MA, Thomas, RH, Van Den Tooren, H, Easton, A, Tharmaratnam, K, Burnside, G, Alam, AM, Castell, H, Boardman, S, Collie, C, Facer, B, Dunai, C, Defres, S, Granerod, J, Brown, DWG, Vincent, A, Marson, AG, Irani, SR, Solomon, T, Michael, BD

“…<p><strong> Conclusion </strong></p>Age, GCS, fever and aetiology can effectively stratify acute seizure risk in patients with encephalitis. These findings can support the development of targeted interventions and aid clinical trial design for antiseizure medication prophylaxis.…”

Fictions of youth: childness in selected West African novels, 1991-2009 by Moellenberg, T

“…</p> <p>Chapter 3 continues to explore the figure of the child as a complex and multivalent symbol. However, it finds that Helen Oyeyemi's <em>The Icarus Girl</em> (2005) and Yaba Badoe's <em>True Murder</em> (2009) do not disavow children's personhood, as Iweala and Jarrett-Macauley appear to do. …”

Genomic analysis and synergistic biocontrol potential of Bacillus thuringiensis MPOB Bt1 with flubendiamide against oil palm bagworm, Metisa plana walker (Lepidoptera: Psychidae) by Mohd Shawal Thakib Maidin, Amalia Mohd Hashim, Ahmad Zuhairi Abdul Malek, Mohamed Mazmira Mohd. Masri, Nurhafizhoh Zainuddin, Raha Abdul Rahim, Syari Jamian

“…The toxicity and synergistic effect of MPOB Bt1 and Fbd suggest a potential strategy for controlling bagworm infestation in oil palm plantations. These findings provide a promising safer alternative to chemical insecticides for sustainable M. plana management in oil palm plantations.…”
Get full text

Antibacterial activity of green silver nanoparticles on the in vitro pathogen infected Eucalyptus pellita plant by Sawalha, Hanadi, Ahmad, Siti Aqlima, Shaharuddin, Noor Azmi, Sanusi, Ruzana, Azzeme, Azzreena Mohamad, Naganthran, Ashwini, De Silva, Catrenar, Abiri, Rambod

“…The focal point of the current research is to use of green synthesised AgNPs as an efficient antibacterial agent that particularly targets in vitro pathogen infections in E. pellita plants. Thus, this study finds that green AgNPs possess potent antibacterial activity and could therefore be developed as a promising antimicrobial agent for the treatment of bacterial infections, including gram-positive and gram-negative bacteria.…”

Mediating role of psychological distress on the relationship between fear of COVID-19 and burnout among healthcare providers: a cross-sectional study in Selangor, Malaysia by Ching, Siew-Mooi, Thurasamy, Ramayah, Cheong, Ai Theng, Yee, Anne, Lim, Poh Ying, Ismail, Irmi Zarina, Ng, Jun Ying, Ooi, Pei Boon, Lee, Kai Wei, Rasina Nilofer, Jabarulla Khan, Zamzurina, Asmuee, Rajini Ann, S. Ratnasingamp, Teoh, See Wie, Hassan, Noor Hasliza

“…Nurses (47.4%) were the largest group, followed by doctors (26%), medical assistants (11.9%), healthcare assistants (7.1%), medical laboratory technicians (6.4%), and drivers (1.3%). The findings revealed that fear of COVID-19 was positively associated with psychological distress, such as depression, anxiety, and stress, as well as burnout. …”
Get full text

The magnificent manifestation of Nd0.7Sr0.3MnO3 ceramics: A comprehensive exploration of different wet chemical routes via sol-gel and thermal treatment methods by Hon, Xiao Tong, Lau, Lik Nguong, Lim, Kean Pah, Awang Kechik, Mohd Mustafa, Chen, Soo Kien, Shabdin, Muhammad Kashfi, Miryala, Muralidhar, Shaari, Abdul Halim

“…The occurrence of magnetoresistance peak in SG suggests a pronounced intrinsic CMR effect, while its absence in TT implies a dominant influence of extrinsic CMR. These findings highlight that the physical properties of the manganite are not only governed by their intragrain properties (TC) but are also influenced by intergrain contributions (TMI) when various synthesis routes were utilised. © 2024 Elsevier B.V.…”
Get full text

Empirical evidence of the relationship between regulatory efficiency, market openness, and bank productivity in economies at different income levels: evidence from selected Asian a... by Kamarudin, Fakarudin, Hussain, Hafezali Iqbal, Mohamad Anwar, Nazratul Aina, Michałek, Janusz, Ahmad Razimi, Mohd Shahril

“…Then, regression analysis was performed utilizing the ordinary least squares (OLS) approach, fixed effect (FE), and random effect (RE) panel multiple regression estimation methods are utilized to measure economic freedoms and other determinants’ effect on banks’ productivity change over time. Findings & value added: The results show that banks in high-income economies are more productive and have higher growth rates than those in upper-and lower-income economies. …”
Get full text

The perception of medical students on the usefulness of the respiratory ventilatory augmented reality (ResVAR) application for learning the respiratory system by Saat, Azmah, O.K. Rahmat, Rahmita Wirza, Ab Razak, Nur Izah, Abas, Razif, Mohd Thani, Suryati

“…Overall, both preclinical and clinical students thought that the ResVAR was a useful teaching tool that helped them better understand the respiratory system. The findings of this study suggest that integration of the ResVAR and other similar applications and software into medical curricula could yield significant advantages for students in terms of enhanced comprehension and study of the respiratory system.…”
Get full text

Genomic analysis and synergistic biocontrol potential of Bacillus thuringiensis MPOB BT1 with flubendiamide against oil palm bagworm, Metisa plana Walker (Lepidoptera: Psychidae) by Maidin, Mohd Shawal Thakib, Mohd Hashim, Amalia, Abdul Malek, Ahmad Zuhairi, Mohd. Masri, Mohamed Mazmira, Zainuddin, Nurhafizhoh, Abdul Rahim, Raha, Jamian, Syari

“…The toxicity and synergistic effect of MPOB Bt1 and Fbd suggest a potential strategy for controlling bagworm infestation in oil palm plantations. These findings provide a promising safer alternative to chemical insecticides for sustainable M. plana management in oil palm plantations.…”
Get full text

The impact of the exercise on the social mentality of the Chinese people by Ji, Shuyu, Zhang, Kaiqi, Xu, Ludan, Wang, Xiaolin, Dong, Delong, Yang, Xiannan

“…We employed Ordinary Least Squares (OLS) multiple linear regression models to construct our analysis. Results The findings indicate that exercise has a positive influence on the social mentality of the Chinese population. …”
Get full text

Identifying erosion risk criteria for coastal city sustainability by using a Hyper-Delphi-hierarchy model: a case study of Kuala Terengganu, Malaysia by Bagheri, Milad, Ibrahim, Zelina Z., Manaf, Latifah Abd, Wolf, Isabelle D., Akhir, M.F., WIAW, Talaat

“…Future research will benefit from incorporating these findings into vulnerability and hazard mapping studies, for example, by adopting weighting factors for GIS layers, to contribute to erosion mitigation planning in coastal cities.…”

Dysfunctional cardiac energy transduction, mitochondrial oxidative stress, oncogenic and apoptotic signaling in DiNP-induced asthma in murine model by Kehinde, Samuel Abiodun, Olajide, Abosede Temitope, Fatokun, Tolulope Peter, Faroud, Dalia, Hadi, Najah R., Elgazzar, Ahmed M., James, Adewale Segun, Ashour, Mohamed H. Mazhar

“…Furthermore, DiNP-induced asthma group has an increased cardiac caspase-3, Bax, c-Myc and K-ras, and p53 while the Bcl2 decreased when compared with control. Overall, the findings indicate that DiNP-induced asthma impairs cardiac functions by induction of key cardiac oncogenes, downregulation of cardiac energy, transduction of enzymes, and promotion of oxidative stress and cellular death. …”
Get full text