Structural basis of RNA binding by leucine zipper GCN4 by Nikolaev, Yaroslav, Pervushin, Konstantin

“…Site-directed mutagenesis of the LZ-GCN4 RNA binding interface showed that substrate binding is facilitated by lysine and arginine side chains, and that at least one nucleophilic residue is located in proximity to the RNA phosphate backbone. …”
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Compact transformer based power combination techniques for millimeter-wave CMOS power amplifiers by Han, Jiangan

“…As an indispensable building block in RF-front-end, compact PAs are highly sought after especially for low cost and high volume production. …”
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Phase separation of a microtubule plus-end tracking protein into a fluid fractal network by Czub, MP, Uliana, F, Grubić, T, Padeste, C, Rosowski, KA, Lorenz, C, Dufresne, ER, Menzel, A, Vakonakis, I, Gasser, U, Steinmetz, MO

“…This process is accompanied by conformational rearrangements in Bik1, leading to at least a two-fold increase in multivalent interactions between its folded and disordered domains. …”

Predicting wealth score from remote sensing satellite images and household survey data using deep learning by Shekhar, Shashank, Singh, Pratibha, Mishra, Rashmi, Kumar, Sunil

“…The most exigent call of the United Nations’ 17 sustainable goals is to end poverty everywhere by 2030. Unlike in the past, when poverty was measured based on data collected through ground-level surveys, the new technology adopted by many developing and developed countries is to estimate the poverty index using remote sensing satellite images with the help of machine learning techniques. …”
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Fast updating feedback from piriform cortex to the olfactory bulb relays multimodal identity and reward contingency signals during rule-reversal by Hernandez, DE, Ciuparu, A, Garcia da Silva, P, Velasquez, CM, Rebouillat, B, Gross, MD, Davis, MB, Chae, H, Muresan, RC, Albeanu, DF

Structural basis for the ligand-dependent activation of heterodimeric AHR-ARNT complex by Diao, X, Shang, Q, Guo, M, Huang, Y, Zhang, M, Chen, X, Liang, Y, Sun, X, Zhou, F, Zhuang, J, Liu, S, Vogel, CFA, Rastinejad, F, Wu, D

“…Crystal structures of the AHR-ARNT-DNA complexes, bound with each of six established AHR ligands, including Tapinarof, 6-formylindolo[3,2-b]carbazole (FICZ), benzo[a]pyrene (BaP), β-naphthoflavone (BNF), Indigo and Indirubin, reveal an unconventional mode of subunit assembly with intimate association between the PAS-B domains of AHR and ARNT. AHR’s PAS-B domain utilizes eight conserved residues whose dynamic rearrangements account for the ability to bind to ligands through hydrophobic and π-π interactions. …”

Fast and accurate detection of Identical-By-Descent segment sharing in large genomic datasets by Saada, J

Legionella pneumophila filamentous morphological form and the generation of novel spherical form upon interaction with protozoan hosts by Chan, Sock Hoai

“…Our investigation showed that filamentation cannot be neatly pegged to a single dominant factor but is promoted under a concerted influence of environmental conditions leaning towards (i) higher than ambient temperatures, at 37-42°C, (ii) static fluid movement, and (iii) with at least a minimal organic content of 5% buffered yeast extract, or equivalent. …”
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Factors influencing behavioural intention to use for E-government websites by Chan, Sook Yin, Chew, Christina Chun Jun, Lam, Kwong Fai

“…We collected survey from 200 respondents who had visited at least one of the Singapore government websites during the past year.…”
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Thermodynamics of complexity and pattern manipulation by Vedral, Vlatko, Gu, Mile, Garner, Andrew J. P., Thompson, Jayne

“…Here, we propose a framework to describe pattern manipulators—devices that convert thermodynamic work to patterns or vice versa—and use them to build a “pattern engine” that facilitates a thermodynamic cycle of pattern creation and consumption. We show that the least heat dissipation is achieved by the provably simplest devices, the ones that exhibit desired operational behavior while maintaining the least internal memory. …”
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Modelling and analysis of lubricated piston skirt-cylinder sub-systems in internal combustion engines by Amirun Rasyid Abu Bakar

“…Dynamic viscosities of 0.01Pas – 0.04Pas was considered as they overlapped with the engine oils available are tested. …”
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The dual GGDEF/EAL domain enzyme PA0285 is a Pseudomonas species housekeeping phosphodiesterase regulating early attachment and biofilm architecture by Eilers, Kira, Yam, Joey Kuok Hoong, Liu, Xianghui, Goh, Yu Fen, To, Ka-Ning, Paracuellos, Patricia, Morton, Richard, Brizuela, Jaime, Yong, Adeline Mei Hui, Givskov, Michael, Freibert, Sven-Andreas, Bange, Gert, Rice, Scott A., Steinchen, Wieland, Filloux, Alain

“…This suggests the N-terminal transmembrane and PAS domains influence the PDE activity in vivo, through modulating the protein conformation.…”
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Application of stock selection strategies on the Singapore market by Li, Xinhao

“…Past research has shown that Value strategy can achieve higher returns as compared to Growth strategy. …”
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Molecular, Genetic, and Process Approaches for Improving Secreted Pharmaceutical Protein Quality in Komagataella phaffii by Yang, Yuchen

“…We further showed the comparability between yeast- and CHO-secreted products, providing a framework for rapid product development with this unconventional yeast. …”
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Is Malaysia ready for an islamist prime minister? by Farish A. Noor

“…The call PAS members for their party leader to Prime Minister should the Pakatan Rakyat coalition win power at the next general election raises two questions: will it erode non-Malay support for the opposition coalition and will it change Malaysia's foreign policy?…”
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Ultrasound discrimination between placenta accreta spectrum and urinary bladder varices by Theophilus, KA-B, Collins, S, Nieto-Calvache, A

“…Differentiating between placenta accreta spectrum (PAS) and urinary bladder varices can be difficult on prenatal US because the 2 conditions have similar appearances. …”

Identifying the interaction between N-WASP, an actin nucleation factor and vinculin, a focal adhesion protein by Ganaesh

“…Although the two-hybrid assay showed interaction between N-WASP and vinculin in yeast cells, vinculin could not be detected in the pull down. …”
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The effect of rare-earth nanoparticles on drug delivery by Li, Linda Shi Wen

“…Cancer, being one of the leading causes of death worldwide, has received much attention for the past century. Utilizing nanoparticles as a drug delivery vehicle has become widely popular in cancer therapy. …”
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Malaysia's 13th general election : prospects and challenges for DAP by Farish A. Noor

“…How will the DAP fare at the coming general election if it has to make compromises with its coalition partners, including the Islamic party PAS that still upholds its vision of eventually creating an Islamikc state in Malaysia.…”
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A study on the extent of Singaporeans' knowledge of their history by Chan Lai Yin Ivy Hannah, Ong Siok Lay Jessie, Tay Siang Ling Hannah

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