Rapid and Scalable Production of Functional SARS-CoV-2 Virus-like Particles (VLPs) by a Stable HEK293 Cell Pool by Puarattana-aroonkorn, Sitthiphol, Tharakaraman, Kannan, Suriyawipada, Disapan, Ruchirawat, Mathuros, Fuangthong, Mayuree, Sasisekharan, Ram, Artpradit, Charlermchai

“…We demonstrated that the production of SARS-CoV-2 VLPs using this cell pool was scalable up to a stirred-tank 2 L bioreactor in fed-batch mode. …”
Get full text

Antigen presentation dynamics shape the antibody response to variants like SARS-CoV-2 Omicron after multiple vaccinations with the original strain by Yang, Leerang, Van Beek, Matthew, Wang, Zijun, Muecksch, Frauke, Canis, Marie, Hatziioannou, Theodora, Bieniasz, Paul D, Nussenzweig, Michel C, Chakraborty, Arup K

“…The Omicron variant of SARS-CoV-2 is not effectively neutralized by most antibodies elicited by two doses of mRNA vaccines, but a third dose increases anti-Omicron neutralizing antibodies. …”
Get full text

What We Should Do Before the Social Bots Take Over: Online Privacy Protection and the Political Economy of Our Near Future by Graeff, Erhardt

“…U.S. states have passed laws to address self-driving cars on public roads (Marcus 2012). And nearer the subject of this paper, the legality of search engine bots (web crawlers) has been openly questioned on grounds of intellectual property protection and trespassing (Plitch 2002). …”
Get full text

Spontaneous emission of a quantum emitter near a Chern insulator : interplay of time-reversal symmetry breaking and Van Hove singularity by Lu, Bing-Sui, Arifa, Kathee Zathul, Hong, Xing Ru

“…We consider the generic problem of a two-level quantum emitter near a two-dimensional Chern insulator in the dipole approximation, and study how the frequency-dependent response and electronic density of states of the insulator modifies the transition rate of the emitter between the ground and excited levels. …”
Get full text

Super-resolution photoacoustic microscopy using a localized near-field of a plasmonic nanoaperture : a three-dimensional simulation study by Park, Byullee, Lee, Hongki, Upputuri, Paul Kumar, Pramanik, Manojit, Kim, Donghyun, Kim, Chulhong

“…In the near future, we will develop the SR-PAM and it will contribute to biomedical and material sciences.…”
Get full text
Get full text

Dynamics of SARS-CoV-2 infection over two epidemic waves in Manaus, Brazil: A serological study of seven thousand blood donors by Alexander, N, Dye, C, Busch, MP, Buss, L, Prete, CA, Brady, OJ, Mee, P, Abrahim, CMM, Crispim, MAE, da Costa, AG, Salomon, T, Mayaud, P, Oikawa, MK, Faria, NR, Sabino, EC

“…Seroconversion was inferred by a mixture model for serial values from the Abbott Architect SARS-CoV-2 nucleocapsid (N) IgG assay. We estimated the number of suspected COVID-19 hospitalizations arising from each infection over calendar time. …”

Pricing data tampering in automated fare collection with NFC-equipped smartphones by Dang, Fan, Zhai, Ennan, Li, Zhenhua, Zhou, Pengfei, Mohaisen, Aziz, Bian, Kaigui, Wen, Qingfu, Li, Mo

Subjects: Get full text

The cellular characterization of SARS-CoV-2 spike protein in virus-infected cells using the receptor binding domain binding specific human monoclonal antibodies by Chan, Conrad En-Zuo, Ng, Ching-Ging, Lim, Angeline Pei-Chew, Seah, Shirley Lay-Kheng, Chye, De-Hoe, Wong, Steven Ka-Khuen, Lim, Jie-Hui, Lim, Vanessa Zi-Yun, Lai, Soak-Kuan, Wong, Pui-San, Leong, Kok-Mun, Liu, Yi-Chun, Sugrue, Richard J., Tan, Boon Huan

“…A human monoclonal antibody panel (PD4, PD5, PD7, SC23, and SC29) was isolated from the B cells of convalescent patients and used to examine the S protein in SARS-CoV-2-infected cells. While all five antibodies bound conformational-specific epitopes within SARS-CoV-2 spike (S) protein, only PD5, PD7, and SC23 were able to bind to the receptor binding domain (RBD). …”
Get full text

Employment of a high throughput functional assay to define the critical factors that influence vaccine induced cross-variant neutralizing antibodies for SARS-CoV-2 by Gu, Yue, Shunmuganathan, Bhuvaneshwari, Qian, Xinlei, Gupta, Rashi, Tan, Rebecca S. W., Kozma, Mary, Purushotorman, Kiren, Murali, Tanusya M., Tan, Nikki Y. J., Preiser, Peter Rainer, Lescar, Julien, Nasir, Haziq, Somani, Jyoti, Tambyah, Paul A., Smith, Kenneth G. C., Renia, Laurent, Ng, Lisa F. P., Lye, David C., Young, Barnaby E., MacAry, Paul A.

“…The scale and duration of neutralizing antibody responses targeting SARS-CoV-2 viral variants represents a critically important serological parameter that predicts protective immunity for COVID-19. …”
Get full text

Clinical course, immunogenicity, and efficacy of BNT162b2 mRNA vaccination against SARS-CoV-2 infection in liver transplant recipients by Tan, Eunice X., Lim, Wen Hui, Thong, Elizabeth, Chavatte, Jean-Marc, Zhang, Jinyan, Lim, Jonathan, Jin, Jocelyn Y., Lim, Daniel R. X., Kang, Jaclyn Y. T., Tang, Ansel Shao Pin, Chan, Kai En, Tan, Caitlyn, Tan, Shi Ni, Nah, Benjamin, Huang, Daniel Q., Wang, Lin-Fa, Tambyah, Paul A., Somani, Jyoti, Young, Barnaby Edward, Muthiah, Mark D.

Subjects: Get full text

Urban flood detection with Sentinel-1 Multi-Temporal Synthetic Aperture Radar (SAR) observations in a Bayesian Framework : a case study for Hurricane Matthew by Lin, Nina Yunung, Yun, Sang-Ho, Bhardwaj, Alok, Hill, Emma M.

Subjects: “…SAR Intensity Time Series…”
Get full text
Get full text

Socioeconomic inequalities in risk of infection with SARS-CoV-2 delta and omicron variants in the UK, 2020-22: analysis of the longitudinal COVID-19 Infection Survey by Razieh, C, Shabnam, S, Dambha-Miller, H, Morris, EJA, Yates, T, Chudasama, Y, Zaccardi, F, Gillies, C, Banerjee, A, Pareek, M, Lacey, B, White, M, Khunti, K, Islam, N

“…<p><strong>Objective</strong> To explore the risk of a positive test result for the delta or omicron variant of the SARS-CoV-2 virus in different occupations and deprivation groups in the UK.…”

Effectiveness and user experience of nose and throat swabbing techniques for SARS-CoV-2 detection: results from the UK COVID-19 National Testing Programme by Futschik, ME, Kulasegaran-Shylini, R, Blandford, E, Harper, S, Chapman, D, Turek, E, Agrawal, S, Phillips, V, Fordham, H, Chan, L, Kidd, M, Dodgson, A, Klapper, PE, Sudhanva, M, Vipond, R, Hopkins, S, Peto, T, Tunkel, S, Fowler, T

“…Background: The UK’s National Health Service Test and Trace (NHSTT) program aimed to provide the most effective and accessible SARS-CoV-2 testing approach possible. Early user feedback indicated that there were accessibility issues associated with throat swabbing. …”

Third harmonic generation from mid-IR to near-IR regions in a phase-matched silicon-silicon-nanocrystal hybrid plasmonic waveguide by Huang, Tianye, Sun, Yunxu, Wu, Tingting, Shum, Perry Ping, Shao, Xuguang

“…The conversion efficiency of third harmonic generation (THG) from mid-IR (3600 nm) to near-IR (1200 nm) regions in a silicon-silicon-nanocrystal hybrid plasmonic waveguide (SSHPW) was calculated. …”
Get full text
Get full text

Imprinting of IgA responses in previously infected individuals receiving bivalent mRNA vaccines (WT and BA.4/BA.5 or WT and BA.1) by Goh, Yun Shan, Fong, Siew-Wai, Hor, Pei Xiang, Loh, Chiew Yee, Tay, Matthew Zirui, Wang, Bei, Salleh, Siti Nazihah Mohd, Ngoh, Eve Zi Xian, Lee, Raphael Tze Chuen, Poh, Xuan Ying, Lee, I. Russel, Rao, Suma, Chia, Po Ying, Maurer-Stroh, Sebastian, Wang, Cheng-I, Leo, Yee Sin, Lye, David C., Young, Barnaby Edward, Ng, Lisa F. P., Renia, Laurent

Subjects: Get full text

Part geometry-driven crystallographic texture control in a 3D-printed austenitic steel – a strategy for near-monocrystalline microstructure generation by Chandra, Shubham, Tan, Xipeng, Kumar, Punit, Ramamurty, Upadrasta

Get full text

Waste to wealth: near-infrared/pH dual-responsive copper-humic acid hydrogel films for bacteria-infected cutaneous wound healing by Zha, Kangkang, Xiong, Yuan, Zhang, Wenqian, Tan, Meijun, Hu, Weixian, Lin, Ze, Cheng, Peng, Lu, Li, Cai, Kaiyong, Mi, Bobin, Feng, Qian, Zhao, Yanli, Liu, Guohui

“…In this study, we explore the ability of HAs to modulate the inflammatory response, particularly macrophage polarization, and the potential underlying mechanism. We fabricate a near-infrared (NIR)/pH dual-responsive Cu-HAs nanoparticle (NP)-based poly(vinyl alcohol) (PVA) hydrogel film loaded with SEW2871 (SEW), a macrophage recruitment agent, to treat bacteria-infected cutaneous wounds. …”
Get full text

Near-IR and mid-IR (1.55 μm – 2 μm) silicon photonics devices on silicon-on-insulator (SOI) platform by Zhang, Zecen

“…Many useful applications have been developed in the near-infrared (NIR) data- and tele- communication band (1.3-1.6 µm), such as sensors, switches, modulators, and various passive devices. …”
Get full text

Real time monitoring of aminothiol level in blood using a near-infrared dye assisted deep tissue fluorescence and photoacoustic bimodal imaging by Anees, Palapuravan, Joseph, James, Sreejith, Sivaramapanicker, Menon, Nishanth Venugopal, Kang, Yuejun, Wing-Kwong Yu, Sidney, Ajayaghosh, Ayyappanpillai, Zhao, Yanli

“…In this work, we introduced an unsymmetrical near-infrared (NIR) squaraine dye (USq) as an exogenous contrast agent for photoacoustic and fluorescence bimodal imaging of thiol variations in live animals. …”
Get full text
Get full text

Virus-like particles of nodavirus displaying the receptor binding domain of SARS-CoV-2 spike protein: a potential VLP-based COVID-19 vaccine by Kumar, Kiven, Tan, Wen Siang, Arshad, Siti Suri, Ho, Kok Lian

“…The efficacy of the initial vaccines based on the ancestral strain of severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) has become a point of contention due to the emergence of new variants of concern (VOCs). …”
Get full text